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MD (Pharmacology), MBBS
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Last updated on:
30 May 2019 | 05:33 PM (IST)
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Avandia 4 mg Tablet


Overview

Introduction of Avandia Tablet

Avandia 4 mg Tablet is a medicine used in the treatment of type 2 diabetes. It helps to lower the blood sugar level and prevents long-term complications of diabetes. It should be used along with regular exercise and a healthy diet for the best results. This medicine was withdrawn from the market in 2010 as it increased the risk of heart attacks and heart-related deaths.

Uses of Avandia Tablet

Avandia Tablet side effects

Common
  • Blurred vision
  • Numbness
  • Bone fracture
  • Respiratory tract infection

How to use Avandia Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avandia 4 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Avandia Tablet works

Avandia 4 mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Avandia Tablet related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Avandia 4 mg Tablet. Taking rosiglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Pregnancy
WEIGH RISKS VS BENEFITS
Avandia 4 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
No information is available on the use of Avandia 4 mg Tablet during lactation. Please consult your doctor.
Driving
SAFE
Avandia 4 mg Tablet does not usually affect your ability to drive.
Kidney
SAFE
Avandia 4 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Avandia 4 mg Tablet is recommended.
Liver
CAUTION
Avandia 4 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Avandia 4 mg Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

What if you miss a dose of Avandia Tablet?

If you miss a dose of Avandia 4 mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Avandia 4 mg Tablet
₹1100/Tablet
Rosicon 4mg Tablet
Glenmark Pharmaceuticals Ltd
₹9.27/Tablet
save 99%
Reglit 4mg Tablet
Dr Reddy's Laboratories Ltd
₹5.94/Tablet
save 99%
₹6.03/Tablet
save 99%
Rositus 4mg Tablet
Aretaeus Pharmaceuticals
₹5.42/Tablet
save 100%
Windia 4mg Tablet
Glaxo SmithKline Pharmaceuticals Ltd
₹8.92/Tablet
save 99%

Expert Advice

  • Avandia 4 mg Tablet has been withdrawn from the market due to an increased risk of heart attack and heart-related deaths.

Interaction with Drugs

Taking Avandia with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Budojet
SERIOUS
Brand(s): Kopram
SERIOUS
Brand(s): Psycool, Proparise
SERIOUS
Brand(s): Zencort-M, Welone
SERIOUS
Brand(s): Nudiglue-C
SERIOUS
Brand(s): Defmark, Zacdef, Ecodef
SERIOUS
Brand(s): Acert, Dipain
SERIOUS
Brand(s): Excrete
SERIOUS
Brand(s): Flotin, Serodep
SERIOUS
Brand(s): Leparox, Prx
SERIOUS

Patient Concerns

Questions Related to Avandia

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Sir/madam Diabetes type--Type-2 Diabetes Im taking 1 tablet in morning after TIFFIN. Tablet--GLYCOMET-GP2 FORTE. This 1 tablet sufficient as my Diabetes checkup results.& My liver Mildly enlarged this is my problem so pls expalin only 1 Tablet wii effect on any parts of my body Pls ExplainFBS-170 PPBS-190
Dr. Sanjay Bhatt
Diabetes Specialist
Need to examine and priscribe medicine for you.Without examine , can't priscribe any medicine in your case.so plz consult doctor near by or can visit our clinic
I have type 2 diabetes. Can I use IME-9 tablets.if yes. Tell me the dosage and when
Dr. Deepak Kumar Soni
Skin Specialist
yes you can usehttps://www.1mg.com/otc/ime-9-tablet-otc3286611-1 Tablet after lunch & dinner,take this medicine along with your treatment
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Do you have any questions related to Avandia 4 mg Tablet?

FAQs

Q. Can Avandia be used along with glimepiride in diabetes?

Avandia when added to Glimepiride in patients with diabetes mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.

Q. How to use Avandia?

Avandia is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.

Q. How does Avandia cause oedema?

Avandia increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.

Q. How does Avandia cause heart failure?

Avandia can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).

Q. Can Avandia be used in depression?

Avandia, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 743.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1236-37.
  4. Rosiglitazone maleate. Research Triangle Park, North Carolina: GlaxoSmithKline; 2007. [Accessed 22 Feb. 2019] (online) Available from:External Link
  5. Rosiglitazone. Philadelphia, Pennsylvania: SmithKline Beecham Pharmaceuticals; 1999. [Accessed 22 Feb. 2019] (online) Available from:External Link
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