Assurans Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Assurans Injection is used to treat pulmonary arterial hypertension. It decreases high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).

Assurans Injection helps to improve your exercise ability. It is given under the supervision of a healthcare professional. You should not stop taking it without consulting your doctor as it may lead to the worsening of your symptoms. However, if it leads to loss of vision in one or both eyes or sudden loss of hearing with ringing sensation in your ear, you should not stop immediately and consult the doctor.

Common side effects of this medicine include flushing, headache, stiffness, and blurred vision. It may also cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how the medicine works.

It can be dangerous to take it along with medicines called nitrates (often given for chest pain). Do not take this medicine if you have severe heart or liver problems, if you have recently had a stroke or heart attack or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems before taking it. You should not drive if this medicine makes you feel dizzy. Avoid drinking alcohol while taking this medicine as it can lead to side effects.

Uses of Assurans Injection

Benefits of Assurans Injection

In Treatment of Pulmonary arterial hypertension (PAH)

Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain, and swelling in your ankles and legs. It is caused by the thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Assurans Injection belongs to a group of medicines called PDE5 inhibitors. It works by relaxing blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy. It is given as an injection under the supervision of your doctor or healthcare professional.

Side effects of Assurans Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Assurans

  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Stiffness
  • Blurred vision

How to use Assurans Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Assurans Injection works

Assurans Injection is a phosphodiesterase (PDE-5) inhibitor. It works by relaxing the blood vessels in your lungs thereby reducing the high blood pressure in the lungs. This allows your heart to work less to pump blood in your lungs.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Assurans Injection.
Pregnancy
SAFE IF PRESCRIBED
Assurans Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Assurans Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Assurans Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Assurans Injection is safe to use in patients with kidney disease. No dose adjustment of Assurans Injection is recommended.
However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated.
Liver
CAUTION
Assurans Injection should be used with caution in patients with severe liver disease. Dose adjustment of Assurans Injection may be needed. Please consult your doctor.
There is limited information available on the use of Assurans Injection in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Assurans Injection
₹1800.0/Injection
Pulmosil 0.8mg Injection
Sun Pharmaceutical Industries Ltd
₹2195/Injection
22% costlier

Quick Tips

  • Assurans Injection is used to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
  • It can help improve your quality of life and exercise ability.
  • Assurans Injection may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Do not use other medicines (nitrates or nitroglycerin) when taking Assurans Injection as it could drop your blood pressure to a dangerous level.
  • Do not consume alcohol while taking Assurans Injection as that may increase the blood pressure-lowering effects of Assurans Injection.
  • Stop taking Assurans Injection and immediately inform your doctor if you notice loss of vision in one or both eyes or sudden loss of hearing with ringing sensation in your ear.
  • Do not stop taking the medication suddenly without talking to your doctor as that may lead to worsening of your symptoms.

Fact Box

Chemical Class
Benzenesulfonamide Derivative
Habit Forming
No
Therapeutic Class
SEX STIMULANTS REJUVENATORS
Action Class
Phosphodiesterase-V inhibitors

Interaction with Drugs

Taking Assurans with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Leonite, Isonit GTN, Nitrogal
LIFE-THREATENING
Brand(s): Isocrate, Cardicap, Sorbidine
LIFE-THREATENING
Brand(s): Monopark, Isotrate, Angitrate
LIFE-THREATENING
Brand(s): Lorandil
LIFE-THREATENING

Patient Concerns

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I have blood clotting in my brain. My treatment is going on using attached medicines. These medicines are very costly. So can I take generic medicines instead of these branded medicines. And how much time it will take to recover from this illness and for how many days these medicines I have to take.
Dr. Vikas Sharma
Neurology
ur choice; but no assurans=ce on quality
Having high Pulmonary Atrial Hypertension
Dr. Nabajit Talukdar
Cardiology
What medicines r u on
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FAQs

Q. Can I get Assurans Injection without a prescription?

No, you need a doctor's prescription to get Assurans Injection since it is a prescription medicine. Your doctor will prescribe it only if they judge that it would be beneficial for you.

Q. Can I take Assurans Injection with paracetamol?

Yes, Assurans Injection can be taken with paracetamol. No interactions between the 2 medicines or any harmful effects have been reported when they are used together.

Q. Can I take Assurans Injection for the rest of my life?

Assurans Injection is a prescription medicine and should only be taken for the duration that is advised by your doctor.

Q. Why is the use of Assurans Injection contraindicated with nitrates?

Use of Assurans Injection is harmful for patients taking nitrates or blood pressure-lowering medicines as their combined use can cause a severe fall in blood pressure, which can also result in death. However, if these medicines are to be taken together then it is advised to keep a time gap of 24 hours between the intake of Penegra and blood pressure-lowering medicines.

Q. Why does Assurans Injection cause a fall in blood pressure (hypotension)?

Assurans Injection has the property of relaxing the smooth muscle of the blood vessels and widening them which can cause a fall in blood pressure (hypotension). So, when used with blood pressure lowering medicines or nitrates, it can cause a severe fall in blood pressure, which could be fatal. Assurans Injection should not be taken if you are taking nitrates for chest pain or you have a history of heart attack or stroke in the past 6 months.

Q. Is Assurans Injection safe to use in patients with diabetes?

Yes, if prescribed by your doctor then Assurans Injection is safe to use in patients with diabetes.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 752-53.
  2. Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 197.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1261-62.
  4. Sildenafil citrate. Sandwich, Kent: Pfizer Limited; 2005 [revised Jul. 2018]. [Accessed 04 Apr. 2019] (online) Available from:External Link
  5. Drugs.com. Sildenafil. [Accessed 04 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of Origin: India

Expires on or after: June, 2021

A licensed vendor partner from your nearest location will deliver Assurans Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹1530
Inclusive of all taxes
12.5 ml in 1 vial
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