Apligraf Injection
View available alternative with same salt composition
Product introduction
Apligraf Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
Apligraf Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Apligraf Injection
- Prevention of Infections after chemotherapy
Benefits of Apligraf Injection
In Prevention of Infections after chemotherapy
Apligraf Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
Side effects of Apligraf Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Apligraf
- Bone pain
- Weakness
- Headache
- Rash
- Nausea
- Increased lactate dehydrogenase level in blood
- Vomiting
- Increased uric acid level in blood
- Oropharyngeal pain
- Hair loss
- Fatigue
- Diarrhea
- Constipation
- Decreased appetite
- Cough
- Breathing problems
- Injection site reactions (pain, swelling, redness)
How to use Apligraf Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Apligraf Injection works
Apligraf Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
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Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Apligraf Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Apligraf Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Apligraf Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Apligraf Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Apligraf Injection may cause fatigue. This may affect your driving ability.
Apligraf Injection may cause fatigue. This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Apligraf Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver
SAFE IF PRESCRIBED
Apligraf Injection is safe to use in patients with liver disease. No dose adjustment is recommended.
What if you forget to take Apligraf Injection?
If you miss a dose of Apligraf Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Apligraf Injection
₹978/Injection
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Lupifil 300mcg Injection
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Emgrast 300mcg Injection
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Zystim 300mcg Injection
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Quick tips
- Apligraf Injection reduces the risk of infection in people treated with chemotherapy.
- It is usually given as a daily injection into the tissue just under the skin or into the vein.
- You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
- Store it in the refrigerator, protect it from light, and don't shake it.
- For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
- Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
- Use caution while driving or doing anything that requires concentration as Apligraf Injection may cause dizziness.
- Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
- Stop taking Apligraf Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
- Apligraf Injection reduces the risk of infection in people treated with chemotherapy.
- It is usually given as a daily injection into the tissue just under the skin or into the vein.
- You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
- Store it in the refrigerator, protect it from light, and don't shake it.
- For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
- Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
- Use caution while driving or doing anything that requires concentration as Apligraf Injection may cause dizziness.
- Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
- Stop taking Apligraf Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-Colony Stimulating Factor (G-CSF)
Interaction with drugs
Taking Apligraf with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Filgrastim from 24 hours before or 24 hours after taking Methotrexate. Please consult with your doctor. Methotrexate may reduce the efficacy of Filgrastim.
Do not consume Filgrastim from 24 hours before and until 24 hours after taking Azathioprine.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood
Do not consume Filgrastim from 24 hours before and until 24 hours after taking Bendamustine.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood
Do not consume Filgrastim from 24 hours before or 24 hours after taking Busulfan. Please consult with your doctor. Busulfan may reduce the efficacy of Filgrastim.
Do not consume Filgrastim from 24 hours before or 24 hours after taking Busulfan. Please consult with your doctor. Busulfan may reduce the efficacy of Filgrastim.
FAQs
Is Apligraf Injection safe?
Apligraf Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
How does Apligraf Injection work?
Apligraf Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
What are the uses of Apligraf Injection?
Apligraf Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.
Does Apligraf Injection cause cancer?
No, Apligraf Injection does not cause cancer.
Why does Apligraf Injection cause bone pain?
The exact cause in unknown, but bone pain is a common side-effect of Apligraf Injection.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Axiommax Oncology Pvt Ltd
Address: A/303, Atrium -1, Andheri - Kurla Road, Mumbai – 400 059 India
Country of origin: India
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₹978
Inclusive of all taxes
MRP₹1073.44 9% OFF
1.0 ml in 1 prefilled syringe
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