Apixazen 5mg Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart. It is used to reduce the risk of stroke and heart attack.

Apixazen 5mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone elective knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases.

Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Apixazen 5mg Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include hematoma, anemia, and nausea.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Apixazen Tablet

Treatment and prevention of Blood clots

Benefits of Apixazen Tablet

In Treatment and prevention of Blood clots

Formation of blood clots blocks one or more veins, usually in your legs. Apixazen 5mg Tablet is used to prevent formation of blood clots near the surface of your skin. It dissolves the clots and also relieves pain and inflammation by increasing the blood flow. This improves the overall healing process. Take it as prescribed by the doctor. The condition usually improves on its own in some time. Additionally, the doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter painkiller and possibly wearing compression stockings.

Side effects of Apixazen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Apixazen

Hemorrhage
Hematoma
Anemia (low number of red blood cells)
Bruise
Nausea

How to use Apixazen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apixazen 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Apixazen Tablet works

Apixazen 5mg Tablet is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Apixazen 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Apixazen 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Apixazen 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Apixazen 5mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Apixazen 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apixazen 5mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Apixazen 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Apixazen 5mg Tablet may be needed. Please consult your doctor.
However, Apixazen 5mg Tablet dose adjustment may not be needed in patients with the mild liver disease.

What if you forget to take Apixazen Tablet?

If you miss a dose of Apixazen 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Apixazen 5mg Tablet

₹51.2/Tablet

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₹22.7/tablet

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₹24.2/tablet

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Pixaflo 5 Tablet

Lupin Ltd

₹17/tablet

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Xapilis 5 Tablet

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₹18.64/tablet

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Quick tips

Apixazen 5mg Tablet can be taken with or without food. Night time administration is not preferable.
It interacts less with food or other medicines. Hence, frequent dose changes are not required.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Apixazen 5mg Tablet temporarily.
Notify your doctor if you have any kidney problem.
Do not stop taking medication without talking to your doctor.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Oral Factor Xa Inhibitors

Interaction with drugs

Taking Apixazen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Bivalirudin (Injection Route) Severe

Concurrent use may increase the risk of bleeding. Bivalirudin may increase the effect of Apixaban. Do not consume Apixaban with Bivalirudin. If concurrent use is essential, watch o... More

Carbamazepine (Oral Route) Severe

Carbamazepine may reduce blood levels and efficacy of Apixaban. Do not consume Apixaban with Carbamazepine. If concurrent use is essential, your doctor may monitor your treatment ... More

Abciximab (Injection Route) Severe

Concurrent use may increase the risk of bleeding. Do not consume Apixaban with Abciximab. If concurrent use is essential, watch out for bleeding and consult your doctor immediatel... More

Bemiparin (Injection Route) Severe

Concurrent use may increase the risk of bleeding. Do not consume Apixaban with Bemiparin. If concurrent use is essential, watch out for bleeding and consult your doctor immediatel... More

Certoparin (Injection Route) Severe

Concurrent use may increase the risk of bleeding. Do not consume Apixaban with Certoparin. If concurrent use is essential, watch out for bleeding and consult your doctor immediate... More

View all drug interactions

Patient concerns

My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.

Dr. Sunil Sekhri

Diabetology

There are blood clots in the brain arteries

In 3 months pregnancy some blood clots have came

Dr. Dharna Gupta

Obstetrics and Gynaecology

Get an USG done urgently

I was pregnant in January. I was feeling all symptoms of being pregnant. When I was undergone SCG test, It was negative. Even my blood report also shows absence of HCG. As I am feeling pregnancy symptoms, I continued to do HCG tests for 3 .5months. During this tenure, I had almost no monthly periods.(only sometimes spots seen). I consulted Gynaecologist for this problems. I had undergone sonography test two times. It was showing some blood clots. Doctor suggested to do Anti Mullerian hormone test for uneven/ stopped period for long time. He also gave tablets for period which was consumed by me and I had period for four days in first week of April. AMH test showed worrying result. It was showing value- 0.7. A lower normal range is 0.7 to .0.9. Doctor suggested to complete three month course of OVARUS (75mg) tables. Is there any worries about lower AMH ? What is the reason for this problem? I have thyroid problem and I am taking Eltroxine 100mg since last 7 years.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Yes low amh shows poor ovarian reserve and it indicates that u should try for pregnancy soon

She is my mother. She is having blood clots in legs as well as arms. These clot does not give any pain. But these also don't vanishes. Please provide me some information what can I do to remove these. She also have blood pressure problem. Please provide remedy for that too. She is afraid of going to doctor. That's why I am asking here. Hope, I will get useful response Thank u

Dr. Deepak Kumar Soni

Ayurveda

Hi kindly need to consult face to face so once consult to your nearest doctor

My penis has some bent to left side when irrected time.I googled that,see there blood clots inside the penis.if any medicine can cure it.? And my penis is around 4 inches.How can increase my penis ?

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello Anu. Slight curve is natural if you don't have pain during sex. Welcome to 1mg. There are several pills cream and pump are marketed you can choose anyone but none of them are proved to be 100%. Personally I suggest you that you try those things but don't depend on or also don't get disappointed. Size of penis has no role in organ of female. Orgasm of female depends on your foreplay and smart act and attachments. So be confident and stop worry about small penis size. If your penis is more that 5 inch erect then it is sufficient. Stop smoking, reduce belly fat, shave pubic hair, take antioxidant, exercise pelvic floor,take multivitamins containing ginseng and arginine.Here I mentioned some of herbal pills choice is yours: opti-men multivitamin etc

FAQs

Can I cut the tablet of Apixazen 5mg Tablet?

If you have difficulty swallowing the whole tablet, the tablet may be crushed and mixed with water, or 5% dextrose in water, or apple juice or apple puree. Remember to crush the medicine just before you take it.

What if I miss a dose of Apixazen 5mg Tablet?

If a dose is missed, the patient should take Apixazen 5mg Tablet immediately and then continue with twice daily intake as before.

What are the side effects of taking Apixazen 5mg Tablet?

Apixazen 5mg Tablet may cause bleeding in eyes, stomach, nose, etc and anemia which may cause tiredness or paleness. It may also lower your blood pressure which may make you faint or have a quickened heartbeat and nausea. Blood tests may show an increase in gamma glutamyltransferase (GGT), which may be due to liver problems.

What is Apixazen 5mg Tablet used for?

Apixazen 5mg Tablet is used to reduce the risk of stroke and blood clots in people who have atrial fibrillation. In atrial fibrillation, the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes. Apixazen 5mg Tablet also helps to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery and treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.

How dangerous is Apixazen 5mg Tablet?

While using Apixazen 5mg Tablet you should be aware of the risks involved such as it can cause excessive bleeding being a blood thinner. Hence, do not stop taking the medication without speaking to your doctor. If you have epidural or spinal anesthesia or a spinal puncture while taking Apixazen 5mg Tablet then you may be at risk of developing a blood clot in or around your spine which can result in paralysis in some patients. Hence, inform the doctor beforehand if you have had any such procedure.

Do I need to stop Apixazen 5mg Tablet before surgery?

Consult your doctor who will tell you whether you have to stop it or not. It will depend on the type of procedure involved. For instance, if there is moderate to high risk of bleeding during the procedure you will have to stop taking Apixazen 5mg Tablet 48 hours before surgery.

Is Apixazen 5mg Tablet a blood thinner?

Yes, Apixazen 5mg Tablet belongs to a class of medicines known as anticoagulant or blood thinner. It prevents your blood from clotting by preventing formation of an important component of blood clotting (factor Xa).

What are the symptoms of overdosage of Apixazen 5mg Tablet?

Apixazen 5mg Tablet, when taken more than the recommended dose, may cause unusual bleeding or bruising, red, brown, or pink urine, red or black, tarry stools and coughing up or vomiting blood or material that looks like coffee grounds. Consult your doctor immediately or seek emergency medical attention in a nearby hospital.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 79-80
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 366-67.
Apixaban. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012. [Accessed 24 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Apixaban. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Apixaban. [Accessed 14 Mar. 2019] (online) Available from:
Apixaban [Prescribing Information]. Verna, Goa, Indoco Remedies Ltd.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
Northwestern Memorial Hospital. patient Education: Apixaban. [Accessed 09 Jun, 2023] (online) Available from:
Drugs.com. Apixaban Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:

Marketer details

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Address: A.O. : 328-A, Tanaji Chowk, New Mill Road, Kurla (West), Mumbai 400070.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.