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Apigat 5 Tablet

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Product introduction

Apigat 5 Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart. It is used to reduce the risk of stroke and heart attack.

Apigat 5 Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases.

Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Apigat 5 Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include low blood pressure, nausea, and skin rash.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Apigat Tablet

  • Treatment and prevention of Blood clots

Benefits of Apigat Tablet

In Treatment and prevention of Blood clots

Formation of blood clots blocks one or more veins, usually in your legs. Apigat 5 Tablet is used to prevent formation of blood clots near the surface of your skin. It dissolves the clots and also relieves pain and inflammation by increasing the blood flow. This improves the overall healing process. Take it as prescribed by the doctor. The condition usually improves on its own in some time. Additionally, the doctor might recommend applying heat to the painful area, elevating the affected leg, using an over-the-counter painkiller and possibly wearing compression stockings.

Side effects of Apigat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Apigat

  • Anemia (low number of red blood cells)
  • Blood in urine
  • Bruise
  • Nausea
  • Nosebleeds
  • Hematoma

How to use Apigat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apigat 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Apigat Tablet works

Apigat 5 Tablet is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Apigat 5 Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Apigat 5 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Apigat 5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Apigat 5 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Apigat 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apigat 5 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Apigat 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Apigat 5 Tablet may be needed. Please consult your doctor.
Dose adjustment is not needed in patients with the mild liver disease.

What if you forget to take Apigat Tablet?

If you miss a dose of Apigat 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Apigat 5 Tablet
₹28.5/Tablet
Apixabid 5 Tablet
Indoco Remedies Ltd
₹18/tablet
37% cheaper
Apivas 5mg Tablet
Micro Labs Ltd
₹28.5/tablet
same price

Quick tips

  • For best results, take Apigat 5 Tablet at the same time every day. It is better to take at night with meals 
  • It interacts less with food or other medicines. Hence, frequent dose changes are not required.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
  • Inform your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • If you are going to have a surgery or dental treatment, you may be asked to stop taking Apigat 5 Tablet temporarily.
  • Notify your doctor if you have any kidney problem.
  • Do not stop taking medication without talking to your doctor. 

Fact Box

Chemical Class
Phenylpiperidines
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Oral Factor Xa Inhibitors

Patient concerns

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My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.
Dr. Sunil Sekhri
Diabetology
There are blood clots in the brain arteries
In 3 months pregnancy some blood clots have came
Dr. Dharna Gupta
Obstetrics and Gynaecology
Get an USG done urgently
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User feedback


FAQs

Q. Can I cut the tablet of Apigat 5 Tablet?

If you have difficulty swallowing the whole tablet, the tablet may be crushed and mixed with water, or 5% dextrose in water, or apple juice or apple puree. Remember to crush the medicine just before you take it.

Q. What if I miss a dose of Apigat 5 Tablet?

If a dose is missed, the patient should take Apigat 5 Tablet immediately and then continue with twice daily intake as before.

Q. What are the side effects of taking Apigat 5 Tablet?

Apigat 5 Tablet may cause bleeding in eyes, stomach, nose, etc and anemia which may cause tiredness or paleness. It may also lower your blood pressure which may make you faint or have a quickened heartbeat and nausea. Blood tests may show an increase in gamma glutamyltransferase (GGT), which may be due to liver problems.

Q. What is Apigat 5 Tablet used for?

Apigat 5 Tablet is used to reduce the risk of stroke and blood clots in people who have atrial fibrillation. In atrial fibrillation, the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes. Apigat 5 Tablet also helps to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery and treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.

Q. How dangerous is Apigat 5 Tablet?

While using Apigat 5 Tablet you should be aware of the risks involved such as it can cause excessive bleeding being a blood thinner. Hence, do not stop taking the medication without speaking to your doctor. If you have epidural or spinal anesthesia or a spinal puncture while taking Apigat 5 Tablet then you may be at risk of developing a blood clot in or around your spine which can result in paralysis in some patients. Hence, inform the doctor beforehand if you have had any such procedure.

Q. Do I need to stop Apigat 5 Tablet before surgery?

Consult your doctor who will tell you whether you have to stop it or not. It will depend on the type of procedure involved. For instance, if there is moderate to high risk of bleeding during the procedure you will have to stop taking Apigat 5 Tablet 48 hours before surgery.

Q. Is Apigat 5 Tablet a blood thinner?

Yes, Apigat 5 Tablet belongs to a class of medicines known as anticoagulant or blood thinner. It prevents your blood from clotting by preventing formation of an important component of blood clotting (factor Xa).

Q. What are the symptoms of overdosage of Apigat 5 Tablet?

Apigat 5 Tablet, when taken more than the recommended dose, may cause unusual bleeding or bruising, red, brown, or pink urine, red or black, tarry stools and coughing up or vomiting blood or material that looks like coffee grounds. Consult your doctor immediately or seek emergency medical attention in a nearby hospital.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 79-80
  2. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 366-67.
  3. Apixaban. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012. [Accessed 24 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Apixaban Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Apixaban. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). Apixaban. [Accessed 14 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
Expires on or after: July, 2023

A licensed vendor partner from your nearest location will deliver Apigat 5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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