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Abciximab

Information

Uses

Abciximab is used in the treatment of unstable angina (chest pain)

How it works

Abciximab prevents platelets from sticking together which decreases the formation of harmful blood clots.

Common side effects

Bleeding in patients receiving blood thinning agents

Available Medicine

Expert advice

  • Do not start abciximab and consult your doctor if you have previously taken abciximab, have serious kidney problems, are above 65 years of age, pregnant or breast feeding.
  • Avoid activities that may cause bruising or injury as there is an increased risk of bleeding with abciximab use.
  • You may be monitored with lab tests, including complete blood cell counts and blood clotting tests while on Abciximab therapy.
  • Seek immediate medical attention if you experience unusual bruising or bleeding (eg, bleeding gums; nosebleeds; bleeding in the eye; blood in the urine; black, bloody, or tarry stools; coughing up blood; vomiting blood or material that looks like coffee grounds; severe or unusual vaginal bleeding); severe stomach pain; confusion; or severe or persistent headache or dizziness.
  • Do not drive or operate machinery as abciximab may cause dizziness.
  • Platelet count should be monitored prior to, during and after treatment with abciximab for prevention of thrombocytopenia (low platelet count in blood).

Frequently asked questions

Abciximab

Q. Is abciximab is a monoclonal antibody?
Yes, abciximab is a murine monoclonal antibody

Q. Is abciximab a Gpiib/iiia receptors antagonist?
Yes, abciximab is a Gpiib/iiia receptor antagonist

Q. What is abciximab used for?
Abciximab is used in combination with other blood thinner drugs to prevent formation of blood clots during and after angioplasty (dilatation of narrowed lumen of blood vessels). It is also used to lower the risk of heart attack before angioplasty in patients with unstable angina (chest pain at rest due to reduced blood supply to heart)

Q. How does abciximab work?
Abciximab works by binding to blood cells called platelets which are responsible for formation of blood clots.


Content on this page was last updated on 11 January, 2017, by Dr. Varun Gupta (MD Pharmacology)