Amfocan 50mg Injection

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Amfocan 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills the infection causing fungi and thus, treats the infection.

Amfocan 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood.

It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Amfocan Injection

Benefits of Amfocan Injection

In Severe fungal infections

Amfocan 50mg Injection works by killing the fungi which can cause serious infections. It is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the fungi and yeast causing the infection are killed and do not become resistant.

In Kala-azar

Kala azar is a disease caused by leishmania parasites mainly by the bite of infected sandflies. Amfocan 50mg Injection helps to kill the infection causing parasites and helps to treat the infection. This medicine is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the parasites are killed and do not become resistant.

Side effects of Amfocan Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amfocan

  • Headache
  • Vomiting
  • Nausea
  • Stomach cramp
  • Fever
  • Anemia (low number of red blood cells)
  • Heartburn
  • Hyperventilation (rapid breathing)
  • Injection site reactions (pain, swelling, redness)

How to use Amfocan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Amfocan Injection works

Amfocan 50mg Injection is an antifungal medication. It kills fungi by destroying the fungal cell membrane.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amfocan 50mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Amfocan 50mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
CONSULT YOUR DOCTOR
Amfocan 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amfocan 50mg Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amfocan 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Amfocan 50mg Injection is recommended.
However, inform your doctor if you have any underlying kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amfocan 50mg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Amfocan Injection?

If you miss a dose of Amfocan 50mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amfocan 50mg Injection
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Quick Tips

  • It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
  • Amfocan 50mg Injection can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
  • Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
  • Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Fact Box

Chemical Class
Aminoglycosides {Polyenes}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal cell membrane active agent

Interaction with Drugs

Taking Amfocan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
SERIOUS
Brand(s): Adesera, Adheb, Adfovir
SERIOUS
Brand(s): Mikasun, Vizocin, Amricin
SERIOUS
Brand(s): Densol
SERIOUS

Patient Concerns

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I have been experiencing fungal infections, I develop rings and rashes and they all itch like anything. I formed scars because of it. I have been taking Grisovin FP 250 mg however as long I take it I am relieved, even if I miss it for 1 day I start getting fungus back. On top of that Grisovin FP is difficult to find now, please suggest.
Dr. Atul Jain
Dermatology
You are having fungal infections severe, you need to change the medicine by skin specialistCan b prescribed under supervisionMeanwhile apply onabet cream twice a day
Mere jangho me khujli hoti hai aur chamdi kala hogaya hai
Dr. Atula Gupta
Dermatology
please send the pictures of affected area.Fungal infection ( probable tinea )Treatment for Fungal Infection:-Stop all other applications. Cap. Itraconazole (Itrasys/ Canditral) 100mg twice daily for 2 weeks. Sertacide Cream for application twice daily for 1 month. Tab. Fexova 180 mg (if required in case of itching) The treatment has to be complete otherwise the condition will recur.Blood Test- Blood Sugar Fasting & PP also Serum Insulin Fasting and PP.
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FAQs

Q. Is Amfocan 50mg Injection fungistatic or fungicidal?

Amfocan 50mg Injection is fungicidal in nature, it acts by killing the fungus

Q. Is Amfocan 50mg Injection light sensitive?

Amfocan 50mg Injection is not light sensitive

Q. What is Amfocan 50mg Injection liposomal?

Liposomal Amfocan 50mg Injection is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amfocan 50mg Injection can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Amfocan 50mg Injection an antibiotic?

Yes, Amfocan 50mg Injection is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q. Is Amfocan 50mg Injection testing dose needed?

Yes, administration of Amfocan 50mg Injection is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q. How is Amfocan 50mg Injection administered?

Amfocan 50mg Injection is either administered as intravenous injection or infusion by a registered medical professional only

Q. How does Amfocan 50mg Injection cause nephrotoxicity and hyperkalemia?

Amfocan 50mg Injection can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
  2. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
  3. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.
  5. Medsacpe. Amphotericin. [Accessed 29 Mar. 2019] (online) Available from:External Link
  6. Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 04 Feb. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6. [Accessed 29 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

8/3, Asaf Ali Road, New Delhi-110002
Country of Origin: India

Expires on or after: July, 2021

A licensed vendor partner from your nearest location will deliver Amfocan 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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1 Injection in 1 vial
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