Alphadopa 500 Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 20 Jan 2026 | 04:47 PM (IST)

Alphadopa 500 Tablet is a medicine used in the treatment of high blood pressure (hypertension). Lowering the blood pressure helps prevent future heart attack and stroke. This medicine is also used to treat high blood pressure during pregnancy.

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General Information

Contains

Methyldopa (500mg)

Marketer

Wockhardt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Alphadopa 500 Tablet can be taken alone or in combination with other medicines. It can be taken with or without food. You may take it at any time of day but try to take it at the same time each day. You should take this medicine as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising up again and increase your risk of heart disease and stroke.

It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake.

Common side effects of this medicine include headache, weakness, dizziness, and dryness in the mouth. Consult your doctor if these side effects bother you.

Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine.

Uses of Alphadopa Tablet

Hypertension (high blood pressure)

Benefits of Alphadopa Tablet

Hypertension (high blood pressure)
Hypertension, or high blood pressure, is a condition in which the force of the blood against artery walls is consistently too high, increasing the risk of heart disease, stroke, and kidney problems. Alphadopa 500 Tablet is used to manage high blood pressure by helping to lower and stabilize it over time. Keeping blood pressure within a healthier range reduces strain on the heart and arteries, thereby helping prevent serious cardiovascular complications and improving overall well-being.

Side effects of Alphadopa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alphadopa

Dizziness
Fatigue
Dryness in mouth
Headache

How to use Alphadopa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alphadopa 500 Tablet may be taken with or without food.
Avoid Alphadopa 500 Tablet with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How Alphadopa Tablet works

Alphadopa 500 Tablet is an alpha-2 agonist. It works by relaxing blood vessels, which makes the heart more efficient at pumping blood around the body.

Quick tips

For best results, take Alphadopa 500 Tablet at the same time every day. Take last dose of the day at bedtime.
May cause dizziness and lightheadedness. If this happens to you, do not drive or use machinery.
Your doctor may monitor liver function. Inform your doctor if you notice yellowing of the skin or whites of the eyes, abdominal pain, nausea and vomiting while taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not discontinue use without consulting your doctor even if you feel better.
Dizziness or fainting may occur, especially when rising from a lying or sitting position. Getting up slowly may help improve the problem.
Eat healthy (low-fat, high-fibre, low-sodium diet), quit smoking, limit alcohol intake, increase your physical activity, watch your weight, and reduce stress.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Alphadopa 500 Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Alphadopa 500 Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

CAUTION

Alphadopa 500 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Alphadopa 500 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Alphadopa 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular blood pressure monitoring is recommended for dose adjustment.

Liver

CAUTION

Alphadopa 500 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Alphadopa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Methyldopa. If concurrent use is essential, please consult your doctor.

Moderate

Baclofen (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, fainting, blurred vision, nausea, fatigue, confusion, cold or clammy skin, shallow breathing or rapid pulse and consult your doctor if you experience them. They may adjust the doses as per the observations.

Moderate

Methylphenidate (Oral Route)

If concurrent use is essential, your doctor may monitor your blood pressure closely. Methylphenidate may reduce efficacy of Methyldopa.

Moderate

Lithium carbonate (Oral Route)

Watch out for symptoms such as impaired coordination, double vision, weakness, dizziness or confusion and consult your doctor if you experience them. Lithium carbonate may raise blood levels of Methyldopa and its active form.

Moderate

Bortezomib (Injection Route)

Your doctor may monitor blood pressure and adjust the dose, if required.

Fact Box

Chemical Class

Phenylpropanoic acids

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Centrally Acting Alpha-2 Agonists

Related lab tests

Kidney Function Test

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 773-74.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 173.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 894.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:

User feedback

Patients taking Alphadopa 500 Tablet

Once A Day

100%

What are you using Alphadopa Tablet for?

Hypertension (high blood pressure)

86%

Others

14%

How much was the improvement?

Excellent

62%

Average

26%

Poor

12%

What were the side-effects while using Alphadopa 500 Tablet?

No Side Effect

28%

Dryness in mouth

22%

Headache

17%

Orthostatic hypotension (sudden lowering of blood pressure on standing)

Sleepiness

How do you take Alphadopa Tablet?

With food

74%

With or without food

22%

Empty stomach

Please rate Alphadopa 500 Tablet on price

Expensive

48%

Average

33%

Not Expensive

18%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wockhardt Ltd
Address: Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Alphadopa 500 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Alphadopa Tablet

Benefits of Alphadopa Tablet

Side effects of Alphadopa Tablet

How to use Alphadopa Tablet

How Alphadopa Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tranylcypromine (Oral Route)

Baclofen (Oral Route)

Methylphenidate (Oral Route)

Lithium carbonate (Oral Route)

Bortezomib (Injection Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

User feedback

Patients taking Alphadopa 500 Tablet

What are you using Alphadopa Tablet for?

How much was the improvement?

What were the side-effects while using Alphadopa 500 Tablet?

How do you take Alphadopa Tablet?

Please rate Alphadopa 500 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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