Allofienz 300mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 13 Oct 2025 | 04:21 PM (IST)

Allofienz 300mg Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body, and it forms crystals that can appear around your joints and kidneys and cause pain. This medicine helps to keep uric acid levels low.

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General Information

Contains

Allopurinol (300mg)

Marketer

Plena Remedies

Storage

Store below 30°C

The content is shown in English

Product introduction

Allofienz 300mg Tablet should be taken with food. You should keep taking it as recommended by your doctor, even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.

Some of the common side effects of this medicine are diarrhea and increased liver enzymes. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction that needs urgent medical attention. Talk to your doctor straight away if you get symptoms of liver disease, including nausea that does not stop, yellowing skin or eyes, or dark urine.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease, or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.

Uses of Allofienz Tablet

Treatment of Gout

Benefits of Allofienz Tablet

Treatment of Gout
Allofienz 300mg Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.

Side effects of Allofienz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Allofienz

Diarrhea
Elevated serum glutamic oxaloacetic transaminase
Elevated serum glutamic pyruvic transaminase
Increased alkaline phosphatase level in blood

How to use Allofienz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Allofienz 300mg Tablet is to be taken with food.

How Allofienz Tablet works

Allofienz 300mg Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

All substitutes for Allofienz 300mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Allofienz 300mg Tablet with food to avoid stomach upset.
Drink plenty of fluids (2-3 liters) daily while on treatment with Allofienz 300mg Tablet.
Notify your doctor if you develop a rash. This could be a sign of an allergy and should go away on discontinuing Allofienz 300mg Tablet.
When you first start taking this medicine, you might have more gout attacks. Do not stop Allofienz 300mg Tablet even on having an acute attack of gout, as that could make an attack worse.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of the eyes or skin, dark urine, or stomach pain.
Do not consume alcohol while taking this medicine, as it may cause your gout to flare up.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Allofienz 300mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Allofienz 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Allofienz 300mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Allofienz 300mg Tablet may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.

Kidney

CAUTION

Allofienz 300mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Allofienz 300mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Allofienz 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Allofienz 300mg Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Allofienz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Didanosine (Oral Route)

Do not consume Didanosine with Allopurinol. Allopurinol may raise blood levels of Didanosine.

Severe

Capecitabine (Oral Route)

Allopurinol may reduce the efficacy of Capecitabine. Allopurinol may reduce the efficacy of Capecitabine.

Moderate

Gliclazide (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function.

Moderate

Carbamazepine (Oral Route)

Watch out for symptoms of Carbamazepine side effects such as nausea, vomiting, sedation, faintness or drowsiness and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Allopurinol may reduce blood levels of Carbamazepine and its active form.

Moderate

Ramipril (Oral Route)

If concurrent use is essential, watch out for symptoms such as skin rash, hives, itching, swelling, shortness of breath, wheezing or dizziness and consult your doctor if you experience them. They may monitor your blood cell count and adjust the doses as per the observations.

Frequently asked questions

What is the best time of the day to take Allofienz 300mg Tablet?

Allofienz 300mg Tablet can be taken at any time of the day, but it should be taken at the same time each day so that you remember to take it. It is usually prescribed once daily and should be taken after meals. If the dose exceeds 300 mg or if your stomach is upset, you can take it in divided doses as advised by your doctor.

Why do I still get gout while taking Allofienz 300mg Tablet?

If you have started taking Allofienz 300mg Tablet, you may experience an increase in attacks of gout (severe pain, swelling, and redness). However, these attacks usually become shorter and less severe after several months of therapy. The possible reason for increased attacks could be the gradual breakdown of uric acid crystals, causing fluctuations in uric acid levels in the blood. To prevent such painful events, your doctor may advise taking colchicine with Allofienz 300mg Tablet, as it can suppress the gouty attacks.

How long does it take for Allofienz 300mg Tablet to lower uric acid levels?

It may take several months before you start feeling better or notice any significant reduction in attacks of gout (severe pain, swelling, and redness). Initially, after starting Allofienz 300mg Tablet, you may experience gouty attacks. Continue taking Allofienz 300mg Tablet even if you do not experience any considerable relief from the attacks. Do not stop taking Allofienz 300mg Tablet without consulting your doctor. Your doctor will prescribe you another medicine along with Allofienz 300mg Tablet to prevent the initial attacks. It may take a while for the body to completely get rid of all uric acid crystals.

What if I take alcohol while taking Allofienz 300mg Tablet?

You should refrain from consuming alcohol while taking Allofienz 300mg Tablet, as this could make your condition worse. Also, you should avoid all foods that are rich sources of protein, as it will help to prevent attacks of gout. Consult your doctor for a detailed list of food items that need to be avoided. It is also recommended that you drink at least 8 glasses of water or other fluids while taking Allofienz 300mg Tablet unless your doctor has advised otherwise.

Does Allofienz 300mg Tablet cause drowsiness?

Yes, Allofienz 300mg Tablet may cause drowsiness in some people. It can even make you feel giddy (dizzy), or you may have problems with coordination. It would be best to avoid driving or operating machinery if you experience these side effects. However, if it is unavoidable, then extreme caution should be exercised while performing such tasks.

Fact Box

Chemical Class

Pyrazolo Pyrimidine Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Xanthine Oxidase Inhibitors

Related lab tests

Creatinine

Creatinine - Spot

Uric Acid

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 638-39.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 996-97.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 40-42.
CiplaMed: Allopurinol [Prescribing Information]. [Accessed 16 Mar. 2025] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Plena Remedies
Address: plot no-17, industrial area (himuda), bhatolikalan, baddi, dist-solan (h.p) 173205

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Allofienz 300mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Allofienz 300mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Allofienz Tablet

Benefits of Allofienz Tablet

Side effects of Allofienz Tablet

How to use Allofienz Tablet

How Allofienz Tablet works

All substitutes for Allofienz 300mg Tablet

ZyLE 300 Tablet

Zyrik 300 Tablet

Zyloric 300 Tablet

Mecnol 300mg Tablet

More Loric 300mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Didanosine (Oral Route)

Capecitabine (Oral Route)

Gliclazide (Oral Route)

Carbamazepine (Oral Route)

Ramipril (Oral Route)

Frequently asked questions

What is the best time of the day to take Allofienz 300mg Tablet?

Why do I still get gout while taking Allofienz 300mg Tablet?

How long does it take for Allofienz 300mg Tablet to lower uric acid levels?

What if I take alcohol while taking Allofienz 300mg Tablet?

Does Allofienz 300mg Tablet cause drowsiness?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Creatinine

Creatinine - Spot

Uric Acid

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests