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Agoprex Tablet

Agomelatine (25mg)

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Agoprex Tablet helps treat depression. It reduces and gradually eliminates the symptoms of depression such as deep sadness, feelings of worthlessness, loss of interest in activities, sleep disturbances, tiredness, feelings of anxiety, and weight changes.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)

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General Information

Contains

Agomelatine (25mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Agoprex Tablet may be taken with or without food preferably at bedtime. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. If you have missed any doses, take it as soon as you remember and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include headache, nausea, fatigue, anxiety, insomnia (difficulty sleeping), and back pain. Other side effects that may also be observed are stomach pain, changes in body weight, diarrhea, and increased liver enzymes. However, these are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or worry you. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking this medicine, please tell your doctor if you suffer from any liver problems or diabetes. If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required. Be vigilant about unusual darkening or any changes in the color of your urine, light-colored stools, yellowing of skin or eyes, pain in the upper right part of your stomach, and unusual fatigue as this could be signs of liver problems.

It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine.

Uses of Agoprex Tablet

Depression

Benefits of Agoprex Tablet

Depression
Depression is a mental health condition marked by persistent sadness, loss of interest, and fatigue. Agoprex Tablet helps improve mood by acting on brain chemicals that regulate the sleep-wake cycle and emotional balance. It may enhance sleep quality without causing daytime drowsiness, reduce feelings of sadness and anxiety, and improve overall emotional well-being, making daily activities more manageable for individuals living with depression.

Side effects of Agoprex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Agoprex

Headache
Nausea
Dizziness
Fatigue
Anxiety
Insomnia (difficulty in sleeping)
Back pain
Abdominal pain
Change in body weight
Diarrhea
Constipation
Sleepiness
Increased liver enzymes

How to use Agoprex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agoprex Tablet may be taken with or without food.

How Agoprex Tablet works

Agoprex Tablet is a melatonin agonist. It works by resynchronizing the sleep-wake cycle that is disturbed in depression.

Quick tips

You have been prescribed Agoprex Tablet for the treatment of depression.
It may take a few weeks for this medicine to start working. Keep taking it as prescribed.
It should be taken at bedtime.
Use caution while driving or doing anything that requires concentration as Agoprex Tablet can cause dizziness and sleepiness.
Avoid consuming alcohol while taking this medicine as that may lead to increased side effects.
You may need regular blood tests to monitor your liver and kidney functions while you are taking this medication.
Inform your doctor if you notice sudden mood changes or develop suicidal thoughts.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Agoprex Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Agoprex Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Agoprex Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Agoprex Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Agoprex Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.

Liver

UNSAFE

Agoprex Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Agoprex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Ciprofloxacin (Oral Route)

Do not consume Agomelatine with Ciprofloxacin. If concurrent use is essential, watch out for symptoms such as headache, nausea, dizziness, fatigue, anxiety, difficulty in sleeping, back pain or abdominal pain and consult your doctor if you experience them. They may adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Agomelatine.

Severe

Ciprofloxacin (Injection Route)

Severe

Fluvoxamine (Oral Route)

Do not consume Agomelatine with Fluvoxamine. Fluvoxamine may raise blood levels of Agomelatine.

Moderate

Conjugated Estrogens (Vaginal Route)

If concurrent use is essential, watch out for symptoms of Agomelatine side effects such as headache, nausea, dizziness, fatigue, anxiety, difficulty in sleeping, back pain or abdominal pain and consult your doctor if you experience them. Conjugated Estrogens may raise blood levels of Agomelatine.

Moderate

Conjugated Estrogens (Oral Route)

Frequently asked questions

What should I inform my doctor before starting treatment with Agoprex Tablet?

Before taking this medicine inform your doctor if you are allergic to agomelatine or any of the other ingredients of this medicine, if your liver does not work properly (hepatic impairment) or if you are taking any other antidepressants or antibiotics.

Can Agoprex Tablet damage my liver?

Yes, this medicine can cause further serious or even life-threatening damage to the liver if you have ever had any liver problems. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).

I was taking an anti-depressant but my doctor has asked me to start taking Agoprex Tablet? Are there any side effects due to changes in medicines?

If your doctor changes your previous antidepressant medicine to Agoprex Tablet, he/she will advise you on how you should discontinue your previous medicine when starting Agoprex Tablet. You may experience discontinuation symptoms like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, feeling sick, being sick, and shaking. These effects are usually mild to moderate and disappear spontaneously within a few days. Inform your doctor immediately if the symptoms worsen.

How to store Agoprex Tablet?

Store in the original package in order to protect from moisture. This medicine does not require any special temperature storage conditions. Keep this medicine out of the sight and reach of children.

Can Agoprex Tablet be given to children?

This medicine is not recommended in the treatment of depression in patients under 18 years of age since its safety and efficacy have not been established in this age group.

Fact Box

Chemical Class

N- acetyl- 2- arylethylamines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Melatonin Receptor Agonists

References

Stahl SM, editor. Agomelatine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 5-8.
Agomelatine. Stoke Poges, Slough: Servier Laboratories Limited; 2009 [revised 12 Dec. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Agomelatine. Les Laboratoires Servier Industrie. [Accesed 19 Mar. 2019]. (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

User feedback

Patients taking Agoprex Tablet

Once A Day

100%

What are you using Agoprex Tablet for?

Depression

77%

Others

23%

How much was the improvement?

Excellent

44%

Average

41%

Poor

15%

What were the side-effects while using Agoprex Tablet?

Headache

33%

Fatigue

17%

Anxiety

17%

No Side Effect

17%

Dizziness

17%

How do you take Agoprex Tablet?

With food

71%

With or without food

29%

Please rate Agoprex Tablet on price

Average

71%

Not Expensive

21%

Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Agoprex Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Agoprex Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Agoprex Tablet

Benefits of Agoprex Tablet

Side effects of Agoprex Tablet

How to use Agoprex Tablet

How Agoprex Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ciprofloxacin (Oral Route)

Ciprofloxacin (Injection Route)

Fluvoxamine (Oral Route)

Conjugated Estrogens (Vaginal Route)

Conjugated Estrogens (Oral Route)

Frequently asked questions

What should I inform my doctor before starting treatment with Agoprex Tablet?

Can Agoprex Tablet damage my liver?

I was taking an anti-depressant but my doctor has asked me to start taking Agoprex Tablet? Are there any side effects due to changes in medicines?

How to store Agoprex Tablet?

Can Agoprex Tablet be given to children?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Agoprex Tablet

What are you using Agoprex Tablet for?

How much was the improvement?

What were the side-effects while using Agoprex Tablet?

How do you take Agoprex Tablet?

Please rate Agoprex Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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