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Rucaparib

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Rucaparib Uses

Rucaparib is used in the treatment of ovarian cancer and prostate cancer.

How Rucaparib works

Rucaparib prevents (by blocking certain proteins) cancer cells from repairing their damaged DNA, causing them to die.

Common side effects of Rucaparib

Nasopharyngitis (inflammation of the throat and nasal passages), Rash, Increased liver enzymes, Decreased appetite, Anemia (low number of red blood cells), Weakness, Gastrointestinal disturbance, Myelodysplastic syndrome, Acute myeloid leukemia (blood cancer)
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Expert advice for Rucaparib

  • Before taking Rucaparib, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
  • After starting your treatment with Rucaparib you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
  • Drink at least two to three-quarters of fluid every 24 hours, unless you are instructed otherwise.
  • To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Females who are able to become pregnant should use effective birth control during the treatment and for at least 6 months after receiving the last dose of Rucaparib.
  • Avoid breastfeeding during the treatment with Rucaparib and for 2 weeks after the last dose.
  • If you are a male with a female partner who is pregnant or able to conceive, use effective birth control (condom) during the treatment and for 3 months after the last dose of Rucaparib.