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03 Jun 2020 | 01:02 PM (IST)
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Afogatran 150 Capsule

Prescription Required
Storage
Store at room temperature (10-30°C)
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Introduction

Afogatran 150 Capsule is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart.

Afogatran 150 Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Afogatran 150 Capsule are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headache, seizures, allergic reactions, changes to your eyesight, and tiredness.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Afogatran Capsule

  • Treatment and prevention of Blood clots

Benefits of Afogatran Capsule

In Treatment and prevention of Blood clots

Afogatran 150 Capsule is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.

Side effects of Afogatran Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Afogatran

  • Bleeding
  • Nausea
  • Stomach pain
  • Indigestion

How to use Afogatran Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Afogatran 150 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Afogatran Capsule works

Afogatran 150 Capsule is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Afogatran 150 Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Afogatran 150 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Afogatran 150 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Afogatran 150 Capsule does not usually affect your ability to drive.
Kidney
CAUTION
Afogatran 150 Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Afogatran 150 Capsule may be needed. Please consult your doctor.
Use of Afogatran 150 Capsule is not recommended in patients with severe kidney disease.
Liver
CAUTION
Afogatran 150 Capsule should be used with caution in patients with liver disease. Dose adjustment of Afogatran 150 Capsule may be needed. Please consult your doctor.

What if you forget to take Afogatran Capsule?

If you miss a dose of Afogatran 150 Capsule, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Afogatran 150 Capsule
₹36.2/Capsule
Dabigza 150 Capsule
Glenmark Pharmaceuticals Ltd
₹30.1/Capsule
save 17%
₹31.43/Capsule
save 13%
Dabigat 150 Capsule
Natco Pharma Ltd
₹31.9/Capsule
save 12%
₹36.3/Capsule
same price
Pradaxa 150mg Capsule
Boehringer Ingelheim
₹71.8/Capsule
98% costlier

Quick Tips

  • Take it as per dose and duration suggested by your doctor. 
  • Afogatran 150 Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
  • If you are going to have a surgery or dental treatment, you may be asked to stop taking Afogatran 150 Capsule temporarily.
  • Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
  • Do not stop taking the medication without talking to your doctor. 

Fact Box

Chemical Class
Benzimidazole derivative
Habit Forming
No
Therapeutic Class
CARDIAC

Patient Concerns

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My father in law is being admitted in hospital due to blood clot in brain. His right leg and arm seems to be paralysed. Doctors in the hospital not briefing us on the problem exactly. Need your second opinion. His age is 67. Having Smoking habit.
Dr. Sunil Sekhri
Diabetology
There are blood clots in the brain arteries
In 3 months pregnancy some blood clots have came
Dr. Dharna Gupta
Obstetrics and Gynaecology
Get an USG done urgently
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Do you have any questions related to Afogatran 150 Capsule ?

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FAQs

Q. When should I take Afogatran 150 Capsule?

Mostly, Afogatran 150 Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours. If you miss a dose of Afogatran 150 Capsule then take it as soon as possible up to 6 hours prior to the next scheduled dose. However, skip the missed dose if your next dose is less than 6 hours away. Never take two doses of Afogatran 150 Capsule at the same time.

Q. Can I drink alcohol with Afogatran 150 Capsule?

Taking alcohol while taking Afogatran 150 Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.

Q. Can Afogatran 150 Capsule cause hair loss?

As compared to other blood-thinning medications, Afogatran 150 Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Afogatran 150 Capsule. Consult your doctor if you face hair loss while taking Afogatran 150 Capsule to rule out any other causes of hair loss.

Q. When will I feel better after taking Afogatran 150 Capsule?

Afogatran 150 Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Afogatran 150 Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Q. Does Afogatran 150 Capsule affect the liver?

Unlike other anticoagulants, Afogatran 150 Capsule usually does not affect the functioning of the liver. But long-term use of Afogatran 150 Capsule may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.

Q. How should I store Afogatran 150 Capsule?

Afogatran 150 Capsule should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.

Q. Can the use of Afogatran 150 Capsule increase the risk of bleeding?

Yes, Afogatran 150 Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Q. Who should not take Afogatran 150 Capsule?

People experiencing any unusual bleeding or people allergic to Afogatran 150 Capsule should not take it. Afogatran 150 Capsule should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced. The use of this medicine is not recommended in patients with severe kidney disease.
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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
  4. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
  5. Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015]. [Accessed 15 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Country of Origin: India

Expires on or after: March, 2021

A licensed vendor partner from your nearest location will deliver Afogatran 150 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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