Afdiloc Injection


Overview

Uses of Afdiloc Injection

Afdiloc Injection is used in the treatment of acidity, heartburn and stomach ulcers.

Afdiloc Injection side effects

Common
  • Sleepiness
  • Headache
  • Tiredness
  • Constipation
  • Diarrhoea

How to use Afdiloc Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Afdiloc Injection works

Afdiloc Injection is a H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Afdiloc Injection related warnings

Alcohol
CAUTION
Alcohol use can increase acid secretion, acid reflux in food pipe causing heartburn and decreasing effect of this drug. Afdiloc Injection can also decrease alcohol breakdown and increase its level in blood.
Pregnancy
PROBABLY SAFE
Afdiloc Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
Afdiloc Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
SAFE
Afdiloc Injection does not usually affect your ability to drive.
Kidney
CAUTION
Afdiloc Injection should be used with caution in patients with kidney disease. Dose adjustment of Afdiloc Injection may be needed. Please consult your doctor.
Liver
CAUTION
Afdiloc Injection should be used with caution in patients with liver disease. Dose adjustment of Afdiloc Injection may be needed. Please consult your doctor.

What if you miss a dose of Afdiloc Injection?

If you miss a dose of Afdiloc Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Afdiloc Injection
Rantac 25mg Injection
J B Chemicals and Pharmaceuticals Ltd
₹1.65/ml of Injection
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Aciloc 25mg Injection
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₹1.77/ml of Injection
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Zinetac 25mg Injection
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₹1.98/ml of Injection
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Aciloc 25mg Injection
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₹1.55/ml of Injection
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Rantac 25mg Injection
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₹3.76/Injection
219% costlier

Expert Advice

  • Afdiloc Injection is a well tolerated and safe medicine with a very low incidence of side effects.
  • Take Afdiloc Injection before going to bed if you are taking this medicine once a day as it is very effective in controlling stomach acid released in the midnight.
  • If you are also taking an antacid, take it two hours before or after taking Afdiloc Injection.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Afdiloc Injection for two weeks or 14 days as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney or liver disease. Dose of your medicine may need to be adjusted.

Interaction with Drugs

Taking Afdiloc with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Miglicon
SERIOUS
Brand(s): Vogmax, Elbose
SERIOUS
Brand(s): Diadose
SERIOUS
Brand(s): Terbicutis
SERIOUS
Brand(s): Exeed, Metcalf, Estimet
SERIOUS
Brand(s): Itraspan, Itzo, Canzit
SERIOUS
Brand(s): Euroglip, Pridex MG, Glimpee
MODERATE
Brand(s): Stoin, Marantin
MODERATE
Brand(s): Diabic, Glicla
MODERATE
Brand(s): Fungis, EF Z, Rocflu
MINOR

Patient Concerns

Questions Related to Afdiloc

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Now I am taking esomeprazole-40mg once in the morning in empty stomach. What is the best medicine in ayurveda for acidity?What should be best medicine in stead of allopathic?
Dr. Aanchal Maheshwari
Ayurveda
there are a lotbof medicines to cure acidity in Ayurveda. syrup smllapitta mishran 10 ml thrice before meal, and powder anago 1 spoon befre meal twice. Anago powder is my self prepared medicine and is very effective. follow a healthy lifestyle, avoid junk spicy oily food
I have acidity &lots of gases problemsI am waiting. Thanku
Dr. Pushkar Mani
Diabetes Specialist
take RABEKIND DSR twice daily 1 hour before breakfast and 1 hour before dinner for 4 weeksTab ZINCOVIT once daily after breakfast for 4 weeksSyrup ULGEL 10ml twice daily with meals for 2 weeks
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FAQs

Q. Does Afdiloc interfere with H. pylori test results?
A significant number of patients infected with Helicobacter pylori can have negative test results if they are using Afdiloc as it interferes with the urea breath test, which is done to identify H. Pylori infection.
Q. Does Afdiloc cause glaucoma?
Afdiloc itself does not cause glaucoma. However, there are some rare reports that Afdiloc can increase the intraocular pressure in patients who have glaucoma. Inform your doctor in case you have glaucoma or high intraocular pressure before taking this medicine.
Q. Can Afdiloc be used to treat gastritis?
Yes, Afdiloc can be used for the short-term treatment of gastritis. It helps by decreasing the amount of acid released into the stomach and relieving stomach pain and acid reflux.
Q. Is Afdiloc safe?
Yes, Afdiloc is safe if used at prescribed doses for the prescribed duration as advised by the doctor. However, there are some very common side effects that you can experience at the doses advised like nausea, abdominal pain, constipation, diarrhea, and flatulence.
Q. Is Afdiloc an over the counter (OTC) drug?
No, Afdiloc is not an over-the-counter product. It is a prescription medicine and is available only when prescribed by a physician.
Q. Can Vitamin B along with Afdiloc?
Yes, Vitamin B can be taken along with Afdiloc. No drug-drug interactions have been reported between this medicine and vitamin B.
Q. Why Afdiloc is given along with vitamin B12?
Long term use of Afdiloc can cause vitamin B12 deficiency as it decreases the acid secretion in the stomach which is required for the absorption of Vitamin B12. To prevent this deficiency, vitamin B12 may be advised by your doctor along with this medicine.
Q. Can a patient with hepatitis C take Afdiloc?
Yes, a patient of hepatitis C can take Afdiloc, however, this should be taken under medical supervision. Afdiloc belongs to the group of drugs called H2 blockers which have been seen to increase the risk of hepatic encephalopathy in hepatitis C patients. So, this group of medicines should be used with caution in patients with underlying liver disease.
Q. Can I take Vitamin D along with Afdiloc?
Yes, Vitamin D can be taken with Afdiloc.
Q. Can the use of Afdiloc cause headache?
Headache is reported as one of the common side effects of Afdiloc. Inform your doctor in case you experience headache for a prolonged duration while taking Afdiloc.
Q. What is the role of Afdiloc in critically ill patients?
Afdiloc may be used in critically ill patients to decrease stomach acid secretion and lower the risk of acid aspiration into the lungs. It also helps in decreasing stomach ulcers and gastrointestinal bleeding in these patients.
Q. What foods should be avoided when you are taking Afdiloc?
You should preferably avoid foods that cause acidity and heartburn as they would aggravate your disease condition, for example: fried foods, prepared in butter or oil, fat rich foods, tomato-based foods and juices, caffeinated drinks like cola, tea, drinks from citrus fruits like lemon water or orange juice and alcohol-containing drinks.
Q. Can Afdiloc be used for reflux esophagitis?
Yes, Afdiloc is effective in the treatment of reflux esophagitis.
Q. Does Afdiloc treat irritable bowel syndrome (IBS)?
Afdiloc is not routinely used for the treatment of irritable bowel syndrome (IBS). It is given if there is associated dyspepsia or increased stomach acid secretion. IBS is managed with a combination of antispasmodics (to relieve stomach pain), laxatives (to relieve constipation), and anti motility drugs (to relieve diarrhea).
Q. Why is Afdiloc given with cancer drugs?
Afdiloc may be used for multiple reasons in cancer patients. It can lower stomach acid volume in patients undergoing chemotherapy to prevent aspiration and lower the risk of stomach ulceration and bleeding. According to some studies, Afdiloc can potentiate white blood cell against cancer cells and can be helpful in the treatment of cancer.
Q. Is Afdiloc used to treat nausea?
Afdiloc is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers and can help in providing relief in nausea that may happen due to acid reflux. It is not used to treat nausea due to any other cause. Rather, nausea is one of the most common side effects of Afdiloc.
Q. What is the benefit of taking Afdiloc with pantoprazole?
Both Afdiloc and pantoprazole lower gastric acid secretion, however, they work by different mechanisms. If you have been advised to take pantoprazole, you can also take Afdiloc initially for rapid relief of heartburn and acid reflux as pantoprazole may take a few days to show its effect and provide relief.
Q. Can I take Afdiloc with pain killers?
Yes, Afdiloc can be taken with painkillers. Afdiloc can help to prevent painkillers induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. Moreover, there are no clinically significant interactions of Afdiloc with painkillers.
Q. What are the serious side effects associated with the use of Afdiloc?
Some serious side effects associated with the use of Afdiloc are bone marrow hypoplasia (decreased formation of blood cell components), anaphylactic shock (severe allergic reactions) sinus bradycardia (lowering of heart rate) and acute pancreatitis (inflammation of the pancreas).
Q. Why does Afdiloc cause diarrhea?
Use of Afdiloc lowers the natural stomach acid which normally helps to kill bacteria. So, use of Afdiloc leads to overgrowth of the harmful bacteria like clostridium difficile which can cause diarrhea. This is known as clostridium difficile–associated diarrhea (CDAD). Inform your doctor if you have loose stools many times in a day and for many days with stomach cramps and fever.
Q. Is Afdiloc effective?
Afdiloc would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. In case you do not find any change in your disease condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.
Q. Can I smoke while taking Afdiloc?
It is better to avoid cigarette smoking when you are taking Afdiloc. As studies have shown that the effectiveness of Afdiloc is lower in smokers compared to non-smokers. Moreover, smoking may add to gastric problems leading to more production of gastric acid.
Q. Can the use of Afdiloc cause iron deficiency?
Yes, use of Afdiloc can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Afdiloc but you can maintain good dietary nutrition so that no deficiency occurs.
Q. Is there any known role of Afdiloc before surgery?
Afdiloc is given as a part of pre-anesthetic medication before surgery to decrease the stomach acid secretion so that stomach acid is not aspirated into the lungs during surgery as this may complicate or delay the procedure.
Q. Does Afdiloc cause flatulence (gas or bloating)?
Flatulence (gas) has been reported as a common side effect of Afdiloc. Although it would be mild to moderate in nature and it goes away once you stop taking Afdiloc.
Q. Is Afdiloc an antihistaminic drug?
Yes, Afdiloc is an antihistaminic drug. It acts on histamine receptors in the stomach and blocks the action of a chemical messenger histamine (causes acid secretion in stomach) and hence decreases the acid production in the stomach.
Q. Can the use of Afdiloc cause constipation?
Yes, the use of Afdiloc can cause constipation. It is one of the common side effect seen with Afdiloc. Taking high fiber diet and plenty of fluids can help in relieving constipation and can also help in decreasing acidity.
Q. Is Afdiloc useful in the prevention of painkiller (NSAID) induced gastric ulcers?
Yes, Afdiloc is useful for the prevention of painkiller (non-steroidal anti-inflammatory drug - NSAID) induced gastric ulcers. These may cause dull pain in the stomach, sudden weight loss, loss of appetite, nausea, vomiting or bloating. Avoid stress and spicy foods as they can make your symptoms worse.

Related Ayurvedic Ingredients

Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
No. 41, 3rd Cross, 5th Block, Rajajinagar, Bengaluru – 560 010, Karnataka , India
One of the following licensed pharmacy from the nearest location with deliver Afdiloc Injection. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts the your request based on valid prescription and availability: MDO, SVS, PPR, RVC, SGN, RSA, TAP, SHN, BBS, EPR, SCP, LCC, KAL, RAC, WDE, AYN, KNH, AVL, KHP, RYL, AAA, HNF, PRL, OWN, SPV, ARV, VMH, RPC, PMA, VOP, UMP, IAD, UPA, ANT, LHA, NTL, RKS, RMR, NNH, BAP, ABP, BMR, SAA, HCP, GHP, ZNT, DPL, VAF, MDH, USF, HLT, RHW, CSE, OHM, NNP, PTI, WPL, MFN, HNP, MMF, SWP, XPR, SIO, MLC, WSI, UHP, CRN, LMS, GPP, PNQ, FIP, DHR, WHP, BBN, SBL, RWL, AGT, GFL, JBT, HAT, LKK, DYL, SHG, TPN, PAP, NSF, GLD, PRC, GBL, HPC, EVP, RDH, PIC, HTV, PSF, APT, SNL, BHC, DLP, BSN, PSE, MKT, RPP, MRS, HHH, NVL, BLP, MDN, AVS, BLE, TRP, BGS, SAH, DZY, RHS, OLT, TAT, SGC, JLI, JIV, KHD, MTM, AMM, NPH, ANP, ATH, BHA, KLC, 2ML, SBA, OWT, BJR, SNH, KCI, VTR, KIM, FGH, DVH, CPK, NLC, ISI, DPP, IMC, SHD, DLY, 1MH, MPC, SMS, SCH, PNT, EPS, ADF, LAG, DYG, NRP, PHC, SRG, AVB, JVO, PRE, GPT, ALC, BTM, NPS, TSC, DRA, HWS, NVY, GGL, VDH, NDP, NSL, SMN, SPD, BDN, HSP, RTL, ZPR, RGH, KHC, RRP, EMB, CTP, UBR, TNH, DFP, XMX, AXM, KHH, SDE, MNS, SRS, MIL, MTD, QTM, RPA, SLN, NSM, IPP, AYU, KMC, SYN, SSR, BNT, OWP, RPI, BHS, FRM, EAN, BDI, GBB, BHP, BMJ, ZVP, EEC, MBN, AHP, JJE, CZT, TYN, OMV, HBV, LIP, VUR, HMP, WHL, VSL, SPF, MJT, BIO, PTP, NXT, STS, PVP, CMD, MAP, ERS, SSS, BJP, SGH, PHN, PLT, ALY, MIP, ENP, SOF, JHC, TOM, LHP, RTN, ZEL, GHR, AAR, SBN, THR, APS, PME, 4IT, OWI, GBC, GVP, OIP, JVN, 9MM, HEX, AFT, STA, SGA, KOS, PRT, VHP, NTB, RWP, VEM, KBC, CNE, FDM, GTF, CAE, RJP, FRS, SVH, MOM, VJS, SIP, RHL, ADE, HIP, ADT, DAO, NCH, KHS, GHC, BLS, NLG, NEO, AMR, ATP, PWN, KRR, TPS, AMH, GDA, NLP, RSS, BHM, CLT, PEN, THP, ZVO, GMA, SBC, NBG, NEW, SJP, RUS, STO, NAS, MKE, ENV, BSL, KIS, SSI, DAD, MDI, GPL, SNG, NXG, ABL, OBS, HSM, JSL, BNC, BRC, GEO, BES, DGN, GNC, ANS, SHC, RDR, HTS, EQN, MSD, NFP, USM, MBP, SDM, GTC, ATL, AGC, IPL, RVA, SLC, PRN, SWA, O4O, DHP, SHA, CHP, WAD, HLP, FTP, AVW, CMC, HGI, SAF, ARD, VSC, AAY, AVC, ESY, QLF, TSS, SYS, MGL, HZF
MRP
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2 ml in 1 vial
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