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03 Dec 2019 | 05:49 PM (IST)
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A-Ret 0.05% Gel



A-Ret 0.05% Gel is a medicine which is a form of Vitamin A that is used to treat acne, which appears as spots or pimples on your face, chest or back. It also helps to smooth rough facial skin and to reduce the appearance of fine wrinkles in the skin.

A-Ret 0.05% Gel reduces excessive oil production of the skin. Ideally, a pinpoint application at night time is recommended for the duration as prescribed by your doctor. The amount you need, and how long you take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor’s instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects.

The most common side effects include irritation, dryness and redness of the skin. They are usually mild and improve as your body get use to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects are rare.

This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects.

Uses of A-Ret Gel

Side effects of A-Ret Gel

  • Skin irritation
  • Dry skin
  • Dry lips
  • Pale red skin
  • Increased sensitivity to light

How to use A-Ret Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How A-Ret Gel works

A-Ret 0.05% Gel is a form of vitamin A. It is used to treat blood cancer as well as acne. To treat blood cancer, it works by slowing the growth of certain types of diseased blood cells, and promotes the growth of normal, mature cells in the bone marrow and blood. This helps to treat blood cancer (acute promyelocytic leukemia). When A-Ret 0.05% Gel is applied on the scalp, it works by promoting the growth of hair follicles, thereby stimulating hair growth. When used on skin, it reduces oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

Safety Advice

No interaction found/established
A-Ret 0.05% Gel may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
A-Ret 0.05% Gel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
No interaction found/established
No interaction found/established
No interaction found/established

What if you forget to take A-Ret Gel?

If you miss a dose of A-Ret 0.05% Gel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
A-Ret 0.05% Gel
₹5.4/gm of Gel
Retop-A 0.05% Gel
Dermo Care Laboratories
₹3.84/gm of Gel
save 29%
Trion Gel
Palsons Derma
₹3.4/gm of Gel
save 37%

Quick Tips

  • You have been prescribed A-Ret 0.05% Gel for the treatment of acne.
  • Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying A-Ret 0.05% Gel.
  • It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor.
  • It may cause stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
  • Avoid exposure to sunlight while using A-Ret 0.05% Gel as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Avoid taking tetracycline (e.g. doxycycline) as it may reduce the A-Ret 0.05% Gel activity.
  • Do not use A-Ret 0.05% Gel if you are pregnant. 
  • Inform your doctor if excessive skin dryness or skin sensitivity take place.

Patient Concerns

I have Acne problem on my face specially on forehead portion. I have cystic acne also very painfull and some acne breakout with pus. I'm too worried for my skin problem. Already I visited many dermatologist they prescribed some medicines but till now no improvement. Already I try Benzyolperoxide 2.5 gel, deriva cms gel, tretinoin 0.05% gel, lynx active gel, doxycycline hyclate 100 mg tablet. Pls. Prescribe me good medicine whichone clear my acne very soon. Pls. Suggest me a good facewash for my acne skin.
Dr. Souvik Sardar
Skin Specialist
Plz visit my clinic in south Kolkata for a face to face consultation Bring all ur previous prescriptionsAmrit pharma (Opp to SBI in touch branch and Raymond's showroom) Southern AVENUE Lake kalibari STOPPAGE Tuesday 4 - 5.30pm Saturday -4 - 5.30pm Phn number - 033 69000116 Take appointment through phone one day before
I've had horrible acne since at least 4 years and decided to get help from a dermatologist 1 year ago. Initially I was prescribed Peroduo gel (Adapalene 0.1%) to be applied before bed and cleargel(clindamycin phosphate) during the day. It didn't seem to do anything at all. I was then put on Tretiva - 20 mg (Isotretinoin) oral and the peroduo gel was changed to peroclin(Clindamycin and benzoyl peroxide) gel which worked a little but not much. The cleargel was changed to Clincure - N (Clindamycin and niacinamide). After this failed, I was told to continue with the dosage of isotretinoin brought up to 30mg per day. This also did not do much. After some research on my own, I decided to try stronger medications by myself. I currently take Tretiva 30 daily and use Azelaic Acid 20% cream during the day and Tazarotene 0.1% (Tazret Forte) before bed and although this has helped a lot compared to what the condition of my face was in the past, the problem still persists. I've also tried topical tretinoin 0.05%(Retino - A) but that didn't make a huge difference. I find the tazarotene works better than the tretinoin cream. At the moment, my pimples have gone down in number but I do have a lot of hyperpigmentation on the sides of my face and redness on my cheeks which is sometimes irritated when touched. I use SPF 40 sunscreen when I go outside and as a moisturizer I use Aquasoft FC by Ajanta pharmaceuticals. I'm also prescribed two facewashes - AHAglow S (Morning) by Torrent and Brevoxyl 4% (Evening) What should I do to fix this problem completely? Should I revisit my dermatologist and ask for a dosage increase in the isotretinoin? Any advice or help is highly appreciated. Thank you very much.
Dr. Atul Jain
Skin Specialist
Don't treat yourselfPhysical examination is needed
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User Feedback


Q. I am taking A-Ret, what should I do if I am planning to become pregnant?

Talk to your doctor if you are planning to become pregnant while taking A-Ret. You should never get pregnant while taking A-Ret because this medicine can harm your baby. The pregnancy needs to be terminated if you become pregnant while taking A-Ret.

Q. Why does A-Ret cause dry skin, dry lips and dry nose, and how to manage them?

One of the most common side effects due to A-Ret is dryness of skin, nose and lips. A-Ret reduces the secretion of oil, thereby, causing dryness of skin. Dryness due to A-Ret can be managed by applying moisturizer or lubricant like Vaseline. You can also apply lip balm to relieve cracked and dry lips.

Q. Can I undergo cosmetic procedures while taking A-Ret?

Your doctor will decide whether you can continue taking or stop taking A-Ret before cosmetic procedures. However, it is advised to not undergo hair removal or laser treatments while using A-Ret. Please ensure that your doctor knows about all the medicines you are taking before any cosmetic procedure.

Q. Is it safe to use A-Ret?

Yes, A-Ret is safe to take when taken according to your doctor's advice. However, like all medicines, even this medicine has some side effects, but it is not necessary that anyone who is taking these medicines might get all of the side effects. Please talk to your doctor if you get any unpleasant effects while taking this medicine.

Q. How long am I supposed to use A-Ret?

Your doctor will decide the duration of your treatment depending on the severity of your disease and the results of your lab tests. On average, the treatment with A-Ret may last for 4-5 months.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1810.
  2. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 35-36.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1395-98.
  4. Tretinoin. Manati, Puerto Rico: Janssen Ortho LLC; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Tretinoin Topical Pregnancy and Breastfeeding Warnings. [Accessed 03 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
A Menarini India Pvt Ltd, B-801, Safal Pegasus, Prahalad Nagar Road, Anand Nagar, Ahmedabad – 380015, Gujarat, India
A licensed pharmacy from your nearest location will deliver A-Ret 0.05% Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
20 gm in 1 tube
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