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Lynparza 100mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Mar 2026 | 11:29 AM (IST)
Lynparza 100mg Tablet is a prescription medicine used in the treatment of ovarian and breast cancer. It works by blocking an enzyme called PARP, which helps fix damaged DNA. By stopping PARP, the medicine prevents cancer cells from repairing themselves, leading them to die off and slowing tumor growth.
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General Information

Contains

Olaparib (100mg)

Marketer

AstraZeneca
The content is shown in English
Lynparza 100mg Tablet image
Lynparza 100mg Tablet image

Product introduction

Lynparza 100mg Tablet may be taken with or without food. Swallow the tablets whole, without crushing, chewing, or splitting them. Take it regularly and at the same time every day to maintain an even level of the medication in your body. Follow your doctor’s instructions on the exact dosage and schedule.


Common side effects  include nausea, fatigue, vomiting, loss of appetite, diarrhea, and dizziness. If you experience nausea or vomiting, eating smaller, more frequent meals and staying hydrated can help. Inform your doctor if these side effects become severe or do not go away. Be cautious about driving or operating heavy machinery if you feel dizzy or fatigued.


While taking Lynparza 100mg Tablet, avoid consuming grapefruit or grapefruit juice as it can increase the risk of side effects. This medicine can cause harm to an unborn baby, so it is important to use effective contraception during treatment and for some time after the last dose. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Regular blood tests are needed to monitor your blood cell counts and liver function during treatment. Do not start any new medications or supplements without consulting your doctor, as they may interact with Lynparza 100mg Tablet.

Uses of Lynparza Tablet

Benefits of Lynparza Tablet

Treatment of Breast cancer
Lynparza 100mg Tablet provides a targeted treatment option that specifically attacks cancer cells while sparing most healthy cells. Clinical studies have shown that Lynparza 100mg Tablet can significantly reduce the risk of cancer progression or recurrence and improve survival rates. By specifically inhibiting the PARP enzyme in cancer cells, Lynparza 100mg Tablet helps to slow the spread of the disease, providing patients with a more effective and less toxic treatment option.
Treatment of Ovarian cancer
Lynparza 100mg Tablet helps prevent the cancer from worsening for a longer period. The medicine is effective in both newly diagnosed cases and in recurrent ovarian cancer, offering a maintenance therapy option that can delay the need for further chemotherapy. This targeted therapy can lead to better management of the disease with a more personalized approach, improving overall outcomes and quality of life for patients.

Side effects of Lynparza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lynparza
  • Nausea
  • Vomiting
  • Fatigue
  • Diarrhea
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Headache
  • Decreased blood cells (red cells, white cells, and platelets)
  • Taste change
  • Cough
  • Breathlessness
  • Indigestion
  • Abdominal pain

How to use Lynparza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lynparza 100mg Tablet may be taken with or without food.

How Lynparza Tablet works

Lynparza 100mg Tablet is an anticancer medication. It works by inhibiting the growth of select tumor cell lines in vitro and decrease tumor growth in both as monotherapy or following chemotherapy.

All substitutes for Lynparza 100mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

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Quick tips

  • Take Lynparza 100mg Tablet exactly as prescribed by your doctor. Do not alter your dose without consulting your doctor.
  • Drinking plenty of fluids can help reduce some side effects, such as nausea and vomiting. Try to drink at least 8-10 glasses of water each day.
  • Lynparza 100mg Tablet can affect your blood cell counts. Ensure you have regular blood tests as recommended by your doctor to monitor for potential issues like anemia or low white blood cell counts.
  • Lynparza 100mg Tablet can harm an unborn baby. Women should use effective contraception during treatment and for a period after the last dose. Men with female partners of reproductive potential should also use effective contraception during treatment and for a specified time afterward.
  • Maintain a healthy lifestyle by eating a balanced diet, getting regular exercise, and managing stress. This can help improve your overall well-being during treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lynparza 100mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Lynparza 100mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Lynparza 100mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Lynparza 100mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Lynparza 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Lynparza 100mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Lynparza with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apalutamide (Oral Route)

Concomitant use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Olaparib.
Severe

Carbamazepine (Oral Route)

Do not consume Olaparib with Carbamazepine. Carbamazepine may reduce blood levels of Olaparib.
Severe

Fosphenytoin (Injection Route)

Do not consume Olaparib with Fosphenytoin. Fosphenytoin may reduce blood levels of Olaparib.
Severe

Phenobarbitone (Oral Route)

Do not consume Olaparib with Phenobarbitone. Phenobarbitone may reduce blood levels of Olaparib.
Severe

Phenobarbitone (Injection Route)

Do not consume Olaparib with Phenobarbitone. Phenobarbitone may reduce blood levels of Olaparib.

Frequently asked questions

Lynparza 100mg Tablet is a prescription medication used to treat ovarian and breast cancer. It works by blocking an enzyme involved in repairing damaged DNA, thereby helping to kill cancer cells.
Before starting Lynparza 100mg Tablet, inform your doctor about any other medications you are taking, any allergies, and your medical history, especially if you have kidney or liver problems, lung issues, or are planning to become pregnant or are breastfeeding.
Some medications may interact with Lynparza 100mg Tablet, affecting how it works or increasing the risk of side effects. Always inform your doctor about all the medications and supplements you are taking to ensure there are no harmful interactions.
Lynparza 100mg Tablet can harm an unborn baby. It is important to avoid pregnancy while taking Lynparza 100mg Tablet and for a period after the last dose. Women should use effective contraception during treatment and for a specified time after the last dose. Breastfeeding is not recommended during treatment with Lynparza 100mg Tablet and for a period after the last dose.
The duration of treatment varies depending on the type of cancer being treated, the patient’s response to the medication, and the presence of any side effects. Your doctor will determine the appropriate length of treatment.

Fact Box

Chemical Class

Phthalazinones

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

  1. Olaparib [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020. [Accessed 17 Jul. 2024] (online) Available from:
  2. Lynparza (Olaparib) [Product Information]. [Accessed 17 Jul. 2024] (online) Available from:
  3. Lynparza (Olaparib) [Product Information]. [Accessed 17 Jul. 2024] (online) Available from:
  4. Olaparib [Prescribing Information]. London, UK: AstraZeneca UK Limited; 2023. [Accessed 17 Jul. 2024] (online) Available from:
  5. Olaparib [Summary of Product Characteristics]. Södertälje, Sweden: AstraZeneca AB; 2022. [Accessed 17 Jul. 2024] (online) Available from:
  6. Olaparib [Prescribing Information]. Mississauga, Ontario: AstraZeneca Canada Inc. 2024. [Accessed 17 Jul. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: United kingdom
A licensed vendor partner from your nearest location will deliver Lynparza 100mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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