Diltiazem 12.5mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 26 Nov 2025 | 01:00 AM (IST)

Diltiazem 12.5mg Tablet is a medicine used to treat high blood pressure, heart-related chest pain (angina), and heart failure. It works by relaxing the blood vessels, so that blood can flow more easily to the heart. Lowering blood pressure also helps prevent future heart attacks and strokes.

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Carvenol 12.5mg Tablet

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Carvedilol (12.5mg)

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General Information

Contains

Carvedilol (12.5mg)

Marketer

General Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Diltiazem 12.5mg Tablet should be taken with food. You should take it in the dose and duration as advised by the doctor. It is important to take it even if you feel well or your blood pressure is controlled. Do not stop this medicine without talking to the doctor, as your condition could get worse.

Making some changes in your lifestyle will help improve your condition. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor.

This medicine is tolerated well by most patients, but it may have a few side effects. These include dizziness, headache, breathlessness, and tiredness. Let your doctor know if these side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any heart or kidney diseases. Pregnant or breastfeeding mothers should also consult their doctor before taking this medicine.

Uses of Diltiazem Tablet

Benefits of Diltiazem Tablet

Treatment of Angina (heart-related chest pain)
Diltiazem 12.5mg Tablet relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

Treatment of Hypertension (high blood pressure)
Diltiazem 12.5mg Tablet works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart to beat with less force. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Treatment of Heart Failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body. Diltiazem 12.5mg Tablet makes it easier for your heart to pump blood around your body and is, therefore, effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

Side effects of Diltiazem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diltiazem

Decreased blood pressure
Headache
Fatigue
Dizziness
Breathlessness
Diarrhea
Increased glucose level in blood
Weight gain

How to use Diltiazem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diltiazem 12.5mg Tablet should be taken with or after food.

How Diltiazem Tablet works

Diltiazem 12.5mg Tablet is an alpha and beta blocker. It works by slowing down the heart rate and relaxing blood vessels, which makes the heart more efficient at pumping blood around the body.

All substitutes for Diltiazem 12.5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Diltiazem 12.5mg Tablet with food for the best result.
Check your blood pressure 1 week after starting Diltiazem 12.5mg Tablet, and inform your doctor if it has not improved.
Diltiazem 12.5mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It is best to avoid drinking alcohol while taking Diltiazem 12.5mg Tablet as it may make the side effects worse.
Do not stop taking Diltiazem 12.5mg Tablet suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Diltiazem 12.5mg Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Diltiazem 12.5mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Diltiazem 12.5mg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Diltiazem 12.5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Diltiazem 12.5mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, inform your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure is recommended for dose adjustment.

Liver

CAUTION

Diltiazem 12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Diltiazem 12.5mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Diltiazem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Aminophylline (Oral Route)

Do not consume Aminophylline with Carvedilol.

Life-threatening

Theophylline (Oral Route)

Do not use Carvedilol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Life-threatening

Theophylline (Injection Route)

Do not use Carvedilol with Theophylline in any form if you have asthma or breathing issues, as it may result in excessive breathlessness or coughing.

Severe

Adrenaline (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Carvedilol may reduce efficacy of Adrenaline.

Severe

Diltiazem (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them.

Frequently asked questions

What happens when you stop taking Diltiazem 12.5mg Tablet?

Diltiazem 12.5mg Tablet needs to be taken regularly as directed by your doctor. Suddenly stopping it may cause chest pain or a heart attack. Your doctor may slowly lower your dose over a period of time before stopping it completely if required.

Does Diltiazem 12.5mg Tablet make you tired?

Yes, Diltiazem 12.5mg Tablet may make you tired as well as dizzy. These may occur initially when you start the treatment or when the dose is increased. If you experience these symptoms, you should not drive or operate machinery.

Can Diltiazem 12.5mg Tablet cause weight gain?

Yes, weight gain is a common side effect of Diltiazem 12.5mg Tablet, but it does not occur in everyone. If you are taking Diltiazem 12.5mg Tablet for heart failure, tell your doctor if you gain weight or have trouble breathing, as this may be a sign of fluid retention.

Can Diltiazem 12.5mg Tablet cause kidney failure?

Use of Diltiazem 12.5mg Tablet in patients with heart failure can rarely lead to deterioration of kidney function. However, Diltiazem 12.5mg Tablet may cause a risk of kidney failure in patients with low blood pressure (systolic blood pressure less than 100 mm Hg), patients with hardening of the arteries and/or having heart disease, or those who already have impaired kidney function. Such patients should be closely monitored during treatment with Diltiazem 12.5mg Tablet. Although kidney functions return to baseline when Diltiazem 12.5mg Tablet is stopped.

Can a diabetic patient take Diltiazem 12.5mg Tablet?

Yes, a diabetic patient can take Diltiazem 12.5mg Tablet, provided that there is a regular check on blood glucose levels. It has been noted that in well-controlled diabetes mellitus with mild to moderate hypertension, Diltiazem 12.5mg Tablet did not have any effect on blood glucose levels. However, it is important to know that using the Diltiazem 12.5mg Tablet class of medicines (beta-blockers) may hide the symptoms of hypoglycemia (decrease in glucose levels), especially an increase in heartbeat or palpitations.<br><br>In addition to that, Diltiazem 12.5mg Tablet may cause worsening of hyperglycemia (increase in blood glucose levels) in patients with heart failure and diabetes. Hence, it is recommended that blood glucose be monitored while initiating, adjusting, or discontinuing the dose of Diltiazem 12.5mg Tablet. Inform the doctor if there is any change in blood glucose levels during Diltiazem 12.5mg Tablet therapy.

Can I take Diltiazem 12.5mg Tablet empty stomach?

It is recommended that you take Diltiazem 12.5mg Tablet with food, as food decreases the rate at which the medicine gets absorbed by the body. This will help reduce the chances of orthostatic hypotension (low blood pressure, which may cause dizziness or fainting when you stand up).

What are the serious side effects of Diltiazem 12.5mg Tablet?

Diltiazem 12.5mg Tablet may cause serious side effects such as fainting, shortness of breath, weight gain, and swelling of the arms, hands, feet, ankles, or lower legs. Some may also experience chest pain, slow or irregular heartbeat, rash, hives, itching, and difficulty breathing and swallowing. If you experience any of these symptoms, call your doctor immediately.

What if I take more than the recommended dose of Diltiazem 12.5mg Tablet?

If you take more than the recommended dose of Diltiazem 12.5mg Tablet, you may experience slow heartbeat, dizziness, fainting, difficulty breathing, vomiting, loss of consciousness, or seizures. Contact your doctor and seek immediate medical help at a nearby hospital.

Who should not take Diltiazem 12.5mg Tablet?

Diltiazem 12.5mg Tablet should be avoided if the patient has severe heart failure and is hospitalized in the intensive care unit or requires certain intravenous medications that help support circulation (inotropic medications). In addition to that, Diltiazem 12.5mg Tablet should be avoided in patients who are prone to asthma or other breathing problems, have a slow heartbeat or irregular heartbeat, have liver problems, or are allergic to Diltiazem 12.5mg Tablet.

Fact Box

Chemical Class

Carbazoles

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Alpha & beta blocker

Related lab tests

Kidney Function Test

References

Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 801.
Robertson D, Biaggioni I. Adrenoreceptor Antagonist Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 159-177.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 214-15.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Carvedilol. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Carvedilol. [Accessed 15 Mar. 2019] (online) Available from:
Singh S, Preuss CV. Carvedilol. [Updated 2023 Mar 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 12 Jun, 2023] (online) Available from:
Carvedilol [Prescribing Information]. Pennington, NJ: Zydus Pharm; 2023. [Accessed 12 Jun. 2023] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: General Pharmaceuticals Pvt Ltd
Address: SARA AFTAB TOWER, Holdings no. 6/1/A (5th Floor), Shamoli, Adabor, Dhaka-1207.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Diltiazem 12.5mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Diltiazem Tablet

Benefits of Diltiazem Tablet

Side effects of Diltiazem Tablet

How to use Diltiazem Tablet

How Diltiazem Tablet works

All substitutes for Diltiazem 12.5mg Tablet

Carvenol 12.5mg Tablet

Cardivas 12.5 Tablet

Carloc 12.5 Tablet

Carvistar 12.5 Tablet

Carzec 12.5 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Theophylline (Oral Route)

Theophylline (Injection Route)

Adrenaline (Injection Route)

Diltiazem (Oral Route)

Frequently asked questions

What happens when you stop taking Diltiazem 12.5mg Tablet?

Does Diltiazem 12.5mg Tablet make you tired?

Can Diltiazem 12.5mg Tablet cause weight gain?

Can Diltiazem 12.5mg Tablet cause kidney failure?

Can a diabetic patient take Diltiazem 12.5mg Tablet?

Can I take Diltiazem 12.5mg Tablet empty stomach?

What are the serious side effects of Diltiazem 12.5mg Tablet?

What if I take more than the recommended dose of Diltiazem 12.5mg Tablet?

Who should not take Diltiazem 12.5mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests