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Accolate 20mg Tablet

Zafirlukast (20mg)
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Accolate 20mg Tablet is a medicine used for the treatment and prevention of asthma. It reduces inflammation in the airways and makes breathing easier.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 03 Dec 2025 | 01:00 AM (IST)
₹222 MRP ₹245.6310% off 
 
 
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General Information

The content is shown in English
Accolate 20mg Tablet image
Accolate 20mg Tablet image

Product introduction

Accolate 20mg Tablet should be taken on an empty stomach, but take it at the same time to get the most benefit. It is advised to have it 2 hours before exercise if you have exercise-induced asthma. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. It does not cure sudden breathing problems, so always carry a medicated inhaler with you.

The most common side effects of this medicine include headache, infection, nausea, and diarrhea.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Generally, you should avoid alcohol while taking this medicine.

Before taking this medicine, you should tell your doctor if you have ever had severe liver problems. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must inform your doctor about pregnancy or breastfeeding.

Uses of Accolate Tablet

Benefits of Accolate Tablet

Treatment and prevention of Asthma
Accolate 20mg Tablet works by reducing and preventing swelling and inflammation in your lungs. It is used to treat and prevent the symptoms of asthma such as tightness in your chest, wheezing, breathlessness and coughing. This means you can carry out your daily activities more easily and more confidently. It may take a few weeks for this medicine to show full effects. Keep taking it as advised by the doctor to get the full benefits.

Side effects of Accolate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Accolate
  • Headache
  • Infection
  • Nausea
  • Diarrhea
  • Generalized pain

How to use Accolate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Accolate 20mg Tablet is to be taken on an empty stomach.

How Accolate Tablet works

Accolate 20mg Tablet works by blocking the action of leukotriene. It lowers inflammation in the airways and nose to prevent asthma.

Quick tips

  • You have been prescribed Accolate 20mg Tablet for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose.
  • Take it on an empty stomach at least 1 hour before or 2 hours after meals.
  • It is a relatively safe medicine with very few side effects.
  • Take Accolate 20mg Tablet 2 hours before exercising if you have exercise-induced asthma.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
  • Do not discontinue use without consulting your doctor, even if you feel better.
  • You have been prescribed Accolate 20mg Tablet for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose.
  • Take it in the evening for better control of asthma or allergy symptoms.
  • It is a relatively safe medicine with very few side effects.
  • Take Accolate 20mg Tablet 2 hours before exercising if you have exercise-induced asthma.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
  • Do not discontinue use without consulting your doctor, even if you feel better.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Accolate 20mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Accolate 20mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Accolate 20mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Accolate 20mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Accolate 20mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, inform your doctor if you have an underlying kidney disease.
Liver

Liver

UNSAFE
Accolate 20mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Interaction with drugs

Taking Accolate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Acenocoumarol (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Warfarin (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Mild

Conjugated Estrogens (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Zafirlukast may decrease the metabolism of Conjugated Estrogens.
Mild

Theophylline (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Theophylline may reduce blood levels of Zafirlukast.
Mild

Conjugated Estrogens (Vaginal Route)

Talk to your doctor if you notice any unusual symptoms. Zafirlukast may decrease the metabolism of Conjugated Estrogens.

Fact Box

Chemical Class

Benzenesulfonamides

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Leukotriene Antagonists

References

  1. Boushey HA. Drugs Used in Asthma. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 349-50
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1502-503.
  3. ScienceDirect. Zafirlukast. [Accessed 01 Apr. 2019] (online) Available from:
  4. Zafirlukast. Wilmington, Delaware: AstraZeneca Pharmaceuticals LP; 2011. [Accessed 23 Jan. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aci Pharma Pvt Ltd
Address: S402a, School Block, Shakarpur, Delhi - 110092

Vendor Details

Country of origin: India
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