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Zafirlukast

Written By Dr. MayankReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Zafirlukast Uses

Zafirlukast is used to prevent asthma prevention, asthma, nasal allergy symptoms and exercise-induced asthma.

How Zafirlukast works

Zafirlukast works by blocking the action of leukotriene. It lowers inflammation in the airways and nose to prevent asthma.

Common side effects of Zafirlukast

Headache, Infection, Nausea, Diarrhea, Generalized pain
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Expert advice for Zafirlukast

  • You have been prescribed Zafirlukast for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose.
  • Take it on an empty stomach at least 1 hour before or 2 hours after meals.
  • It is a relatively safe medicine with very few side effects.
  • Take Zafirlukast 2 hours before exercising if you have exercise-induced asthma.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
  • Do not discontinue use without consulting your doctor, even if you feel better.
  • You have been prescribed Zafirlukast for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose.
  • Take it in the evening for better control of asthma or allergy symptoms.
  • It is a relatively safe medicine with very few side effects.
  • Take Zafirlukast 2 hours before exercising if you have exercise-induced asthma.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
  • Do not discontinue use without consulting your doctor, even if you feel better.

Frequently asked questions for Zafirlukast

Zafirlukast is leukotriene receptor antagonist used to relieve difficulty in breathing during asthma
No. Singulair is proprietary (brand) name for montelukast drug, a leukotriene receptor blocker similar to Zafirlukast
Yes. Zafirlukast is gluten free. However, please refer to package insert of the prescribed brand before use
Zafirlukast has not been reported to cause weight gain.