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Zafirlukast is used to prevent asthma.

How it works

Zafirlukast belongs to a group of medicines called leukotriene antagonists. Certain natural substances (leukotrienes) released in response to allergy cause swelling and narrowing of airways, thereby, causing difficulty in breathing. Zafirlukast blocks the action of leukotrienes, relaxes blocked airways, and eases breathing.

Common side effects

Liver enzyme increased, Abdominal pain, Hormone imbalance, Allergic reaction, Slow growth in children and teenagers, Headache, Muscle pain, Nausea, Sore throat, Vomiting


Expert advice

  • Zafirlukast should not be taken along with meals.
  • Do not take zafirlukast to treat sudden (acute) asthma attacks.
  • If your asthma gets worse while you are taking zafirlukast, follow the advice that your doctor has given you for treating sudden (acute) asthma attacks and see your doctor as soon as possible.
  • Do not stop taking zafirlukast even when you are feeling well (symptom free), unless your doctor tells you so.
  • Take special care before taking zafirlukast if you are smoker or have kidney problems.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions


Q.Is zafirlukast an antihistamine or a steroid or a blood thinner?
Zafirlukast is leukotriene receptor antagonist used to relieve difficulty in breathing during asthma

Q.Does Singulair contain zafirlukast?
No. Singulair is proprietary (brand) name for montelukast drug, a leukotriene receptor blocker similar to zafirlukast

Q.Is zafirlukast gluten free?
Yes. Zafirlukast is gluten free. However, please refer to package insert of the prescribed brand before use

Q.Does zafirlukast cause weight gain?
Zafirlukast has not been reported to cause weight gain.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)