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Viral Marker Screening (HIV, HBsAg, Anti-HCV)

Also referred as
Triple H (HIV
+5
HBV
HCV)
HIV Combo+HbsAg+Anti-HCV
Screening-CMIA/CLIA
Performed by : CMIA/ CLIA
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The Viral Marker Screening (HIV, HBsAg, Anti-HCV) is a group of blood tests used to detect the presence of certain viral infections in the body. This screening helps identify if a person has been infected with hepatitis B, hepatitis C and human immunodeficiency virus (HIV). 

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Blood
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TATA 1mg Labs is a cutting-edge facility delivering top-quality diagnostic services right to your doorstep. We take pride in three core values: Assured Quality, Best Prices and Timely Reports. Transparency is at the heart of our operations, ensuring our customers always have clear and reliable information. Our dedicated team is committed to offering an exceptional customer experience and continually innovates to meet and exceed customer expectations.
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Understanding Viral Marker Screening (HIV, HBsAg, Anti-HCV)

HIV causes acquired immunodeficiency syndrome (AIDS). It attacks the immune cells that help the body fight infection, making an infected person more vulnerable to other infections and diseases. Hepatitis B and C are highly contagious liver infections. Hepatitis B is caused by hepatitis B virus (HBV) and hepatitis C  is caused by hepatitis C virus (HCV). Chronic HBV or HCV infections can lead to liver damage and other complications. A Viral Marker Screening (HIV, HBsAg, Anti-HCV) test detects the presence of viral markers, including antigens and antibodies, produced by the body in response to hepatitis B, hepatitis C, or HIV infections.

People with HIV are most likely to get infected by chronic hepatitis. This co-infection causes more liver-related health problems. Hence, it is important to identify these risks early. A viral marker screening test can help detect these infections. It also helps in taking preventive steps and seeking medical care if needed.

Your doctor may suggest this test if you have risk factors for HIV, HBV, or HCV infections. Risk factors may include:

  • A weakened immunity
  • Unsafe sexual practices
  • Intravenous drug use
  • Occupational exposure to blood
  • Potential exposure through medical procedures. 

Additionally, this test is also done in pregnant women as a part of prenatal care. This is because infections like HIV, Hepatitis B, and Hepatitis C can be passed from the mother to the baby during pregnancy, childbirth, or breastfeeding.

Fasting is not needed for viral marker screening tests. You can eat and drink as per your  daily routine. Let your doctor know about all the medications you are taking, as some of them can affect the test results. Also, a duly filled consent form is mandatory for sample collection.

 

Test results depend upon various factors such as clinical history, time of sample collection, etc. Discuss your specific test results with your doctor. Based on your test results, doctors may suggest some lifestyle adjustments, prescribe medications to manage your condition, and develop a holistic treatment plan.

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What does Viral Marker Screening (HIV, HBsAg, Anti-HCV) measure?

Contains 3 tests

The Viral Marker Test (HIV, HBsAg, Anti-HCV) is a blood test that helps detect serious viral infections such as HIV, Hepatitis B, and Hepatitis C. It measures specific markers in the blood that appear when a person is infected with these viruses.

  • HIV antigen and antibody test looks for the virus that attacks the immune system.
  • HBsAg (Hepatitis B surface antigen) test checks for Hepatitis B infection.
  • HCV test detects antibodies against the Hepatitis C virus, showing if a person has been exposed to it.

This test helps in early detection of infections, even when symptoms are not present. It is especially useful before surgeries, blood transfusions, during pregnancy, and in high-risk individuals. Early diagnosis helps in preventing the spread of infections and allows timely medical care.

The Hepatitis C Virus (HCV) Antibody test determines the status of current hepatitis C virus (HCV) infection or past HCV infection that has been resolved. This test, therefore, helps your doctor to guide an appropriate treatment plan. HCV causes liver inflammation and is classified into acute hepatitis infection and chronic hepatitis infection.

  • Acute hepatitis C: This occurs in the first six months after exposure to the hepatitis C virus. In the early stage of the infection, acute hepatitis C is mild and may cause no symptoms. For this reason, most people do not know they have this infection.
  • Chronic hepatitis C: If your body is unable to fight off the virus, you can develop a chronic hepatitis C infection. Progression from acute to chronic hepatitis C is common, occurring in about 75-85% of patients. Detecting chronic hepatitis C at the early stage is important to prevent future complications, such as liver failure, and initiate effective treatment.

The Hepatitis C Virus (HCV) Antibody test is used for screening for anti-HCV antibodies. A reactive result needs to be confirmed by other more specific NAT/ nucleic acid tests before final diagnosis.

 

Know more about Hepatitis C Virus (HCV) Antibody

The Hepatitis B Surface Antigen (HBsAg) test detects HBsAg, a protein on the surface of the hepatitis B virus (HBV), in the blood. It is an important screening test for HBV infection. A reactive result needs follow-up with additional tests, such as anti-HBs and total anti-HBc antibodies, and can be confirmed with HBV DNA testing by PCR. This test helps identify individuals who may need medical treatment and supports measures to prevent the spread of hepatitis B. The test uses automated chemiluminescence immunoassay (CMIA/CLIA) technology, which may vary slightly across laboratories.

Know more about Hepatitis B Surface Antigen (HBsAg)

An HIV Combo (Antigen And Antibody) Test simultaneously detects HIV p24 antigen and antibodies associated with HIV 1 & 2. The HIV p24 antigen is the most abundant HIV protein. Its detection is used clinically to diagnose an HIV infection early on since HIV-specific antibodies are not detectable in a very recently acquired infection.

HIV-1 was discovered first and is the most widespread. HIV-2 is more than 55% genetically different from HIV-1. The transmission rate of HIV-2 is also slower than HIV-1. 

Know more about HIV Combo (Antigen And Antibody) Test

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Viral Marker Screening (HIV, HBsAg, Anti-HCV) test price for other cities

Price inBangaloreRs. 1709
Price inNew DelhiRs. 1430
Price inMumbaiRs. 1880
Price inKolkataRs. 1709
Price inHyderabadRs. 1409
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Samples are transported securely to our accredited labs with world-class machines for testing by qualified experts.
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FAQs related to Viral Marker Screening (HIV, HBsAg, Anti-HCV)

The Viral Marker Screening (HIV, HBsAg, Anti-HCV) test is a screening test done if you exhibit signs and symptoms suggestive of viral hepatitis B or C and HIV infections. It can be done before all elective or emergency procedures and during pregnancy. This test is also suggested for people who have higher risk factors like sharing needles, abusing intravenous drugs, and indulging in unprotected sexual activities.
The symptoms that require a viral marker screening test may vary from person to person. Symptoms usually depend on the type of virus a person is exposed to. However, Most common symptoms that may need a viral marker test are flu-like symptoms (fever, headache, vomiting, abdominal pain), jaundice symptoms (like yellowing of the skin and the whites of the eyes), unexplained weight loss, night sweats, persistent cough rashes on the skin, etc.
A trained professional will clean your skin and take a blood sample from a vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.
No, the viral marker screening test is generally safe with minimal risks. You may feel slight discomfort during blood sample collection, but serious complications are rare.
No fasting is required for the viral marker screening test. However, it is essential to follow any specific instructions from your healthcare provider.
This test is only an initial screening test for detecting HbsAg, HCV antibodies and HIV (p24 antigen and HIV 1&2 antibodies). However, this is just a preliminary screening. It is important to undergo more specific tests such as Nucleic Acid Tests (NAT), including HCV RNA and HBV DNA, as recommended by the CDC. For HIV, as per NACO guidelines, all initially reactive samples are tested using three different methods before confirming the result. In some cases, a Western Blot Test may be used for further confirmation.
Hepatitis B can be best prevented by vaccination. The hepatitis B vaccine is safe and effective and should be given in three doses for full protection (at 0, 1, and 6 months).
There is no vaccination available for hepatitis C. However, the best way to prevent hepatitis C infection is by avoiding activities that can spread the disease, especially injecting drugs with non-sterile injection equipment, practicing unsafe sex, etc.
An HIV infection is not curable, but proper treatment can be started if the infection is diagnosed at an early stage. Antiretroviral therapy (ART) is used to treat the infection. This therapy helps reduce the levels of the virus in the body, which will improve health.
These viruses can spread through: 1) Blood-to-blood contact (e.g., sharing needles) 2) Unprotected sex 3) From mother to child during childbirth 4) Through infected blood or organ transplants
Tata 1mg ensures accurate lab test results through certified laboratories. Tata 1mg uses advanced technology and adheres to stringent quality control measures. This commitment to high standards guarantees reliable results.
References
  1. Leoni MC, Ustianowski A, Farooq H, Arends JE. HIV, HCV and HBV: A Review of Parallels and Differences. Infect Dis Ther. 2018 Dec;7(4):407-419. [Accessed 11 Oct. 2023]. Available from:
  2. Sharma V, Ramachandran VG, Mogha NS, Bharadwaj M. Hepatitis B & C virus infection in HIV seropositive individuals & their association with risk factors: A hospital-based study. Indian J Med Res. 2018 Jun;147(6):588-593. [Accessed 11 Oct. 2023]. Available from:
  3. Hepatitis B & C [Internet]. HIV.gov; 20 Sept. 2022 [Accessed 11 Oct. 2023]. Available from:
  4. People Coinfected with HIV and Viral Hepatitis [Internet]. CDC; 21 Sept. 2020 [Accessed 12 Oct. 2023]. [Accessed 11 Oct. 2023]. Available from:
  5. Mohammadi M, Talei G, Sheikhian A, Ebrahimzade F, Pournia Y, Ghasemi E, Boroun H. Survey of both hepatitis B virus (HBsAg) and hepatitis C virus (HCV-Ab) coinfection among HIV positive patients. Virol J. 2009 Nov 18;6:202. [Accessed 11 Oct. 2023]. Available from:
  6. Hepatitis C [Internet]. WHO; 12 July 2023 [Accessed 12 Oct. 2023]. Available from:
  7. Hepatitis B [Internet]. WHO; 12 July 2023 [Accessed 12 Oct. 2023]. Available from:
  8. HIV and AIDS [Internet]. WHO; 13 July 2023 [Accessed 11 Oct. 2023]. Available from:

Other tests

Recommended for everyone
This package is designed with everyone’s overall health considerations in mind, offering assessments to address a wide range of wellness needs.
Package can be booked by :
Men
Women
Contains 3 tests
Hepatitis C Virus (HCV) Antibody
Hepatitis B Surface Antigen (HBsAg)
HIV Combo (Antigen And Antibody) Test
Report delivery
Standard time
24 hrs
For slots after 11 AM, report will be delivered in 36 hours.
Samples required
Blood
Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.
Preparations
1
A duly filled Consent form for HIV testing & Pre-test counselling (Annexure - CR/01) is mandatory.
2
🍽 No fasting
Why is this test booked?
1
To detect the presence of Human Immunodeficiency Virus (HIV).
2
To detect the presence of Hepatitis B Virus (HBV), and Hepatitis C Virus (HCV).
3
In individuals with symptoms like loss of appetite, joint pain, dark urine, abdominal pain, nausea, vomiting, mild fever, pale skin tone, etc.
4
To screen individuals with risk factors like weak immunity, unsafe sexual practices, intravenous drug use, occupational exposure to blood, etc.
5
Before blood transfusion or organ donation to ensure safe transfer.
6
As a part of prenatal care in pregnant women.
7
As a part of pre-operative screening tests.
8
In individuals already diagnosed with HIV, to check for co-infections with Hepatitis B or C.
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