Rheumatoid Factor - Quantitative

Rheumatoid arthritis, also known as RA, is an autoimmune (a condition in which the body's natural defense system mistakenly attacks normal/healthy cells) and an inflammatory condition that causes inflammation (painful swelling) of the joints. In addition to the joints, RA sometimes also affects other body parts, including skin, eyes, lungs, or heart. 

Rheumatoid factor (RF) is an antibody the immune system produces that targets healthy tissues, especially in the joints. The Rheumatoid Factor - Quantitative test assesses the level of rheumatoid factor in the blood. Elevated RF levels may indicate the presence of autoimmune conditions, most notably rheumatoid arthritis. However, not everyone with RF autoantibodies has RA because RF can also be found in healthy individuals in a small percentage, particularly in aging individuals.

Your doctor may suggest the Rheumatoid Factor - Quantitative test if you show signs and symptoms of RA, such as pain, warmth, swelling, morning stiffness in the joints, nodules under the skin, etc. This test may also be done if symptoms suggest Sjogren's syndrome, such as parched mouth, eyes, and joint and muscle pain. The quantitative aspect of the test aids in assessing disease severity, response to treatment, and monitoring the progression of the disease.

Usually, no special preparation is required for an RF test; eat and drink as per your daily routine. Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Higher-than-normal levels of rheumatoid factor may suggest the presence of autoimmune conditions, but it is not specific to any particular disease. Further testing and clinical evaluation are needed for a definitive diagnosis. Talk to your doctor about your specific results. The test results will help them determine your medical condition and formulate your treatment plan.