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Hepatitis B Surface Antigen (HBsAg)

Hepatitis B Surface Antigen (HBsAg)

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HBsAg Screening
HBsAg Screening Qualitative
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The Hepatitis B Surface Antigen (HBsAg) is a screening test to detect the presence of hepatitis B surface antigen (HBsAg) in the blood. This test helps detect recent infection, previous exposure to the Hepatitis B virus (HBV), and helps monitor treatment response.

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Understanding Hepatitis B Surface Antigen (HBsAg)

The Hepatitis B Surface Antigen (HBsAg) test detects the presence of the hepatitis B virus (HBV) in the body. It detects the hepatitis B surface antigen in the blood, indicating an active infection. This test is crucial for early diagnosis, treatment planning, and preventing the spread of hepatitis B.

Hepatitis B is a serious liver infection caused by the hepatitis B virus (HBV). It can spread through contact with infected body fluids like blood, saliva, vaginal fluids, and semen. It can also be passed from a mother to her baby during childbirth.

HBsAg is a protein on the surface of the hepatitis B virus (HBV) that appears in the blood within a few weeks of infection. It is one of the earliest markers of hepatitis B and indicates that a person is infectious. Many people do not show symptoms initially, but some may experience fever, nausea, vomiting, loss of appetite, stomach pain, joint pain, dark urine, pale stools, and yellowing of the skin and eyes (jaundice). Persistent HBsAg may indicate chronic hepatitis B or carrier status.

The Hepatitis B Surface Antigen (HBsAg) test is recommended for people who show signs of hepatitis, those at higher risk of hepatitis B (like healthcare workers, people using injectable drugs, or those with multiple sexual partners), during routine health checkups, before surgery, or for job screenings, after vaccination, and for babies born to hepatitis B-infected mothers. Pregnant women are also tested to prevent the virus from being passed to their baby. Early detection helps start treatment early and prevent serious liver problems like cirrhosis or cancer.

No special preparation is needed for this test, and you can eat and drink normally. Please inform your doctor about any medications or recent vaccinations, and provide a complete medical history to help them accurately interpret the results. 

Lab test results require expert interpretation; therefore, never self-medicate at home solely based on these results. Always consult a doctor for a proper understanding of the test results.

What are the Symptoms or Conditions That May Require a Hepatitis B Surface Antigen (HBsAg) Test?

You may need the Hepatitis B Surface Antigen (HBsAg) test if you experience:

  • Fatigue, jaundice, or abdominal discomfort
  • Nausea, vomiting, or unexplained weight loss
  • Dark-colored urine or pale stools
  • Liver enzyme abnormalities in routine blood tests

You may also need the test if:

  • You came into contact with the blood or body fluids of someone with hepatitis B
  • You have multiple sexual partners or take part in high-risk activities
  • You need a check before surgery, medical procedures, or organ transplants
  • Your doctor wants to monitor your liver health or check how well your hepatitis B vaccination is working

When Would I Need a Hepatitis B Surface Antigen (HBsAg) Test?

You may need the Hepatitis B Surface Antigen (HBsAg) test to:

  • Detect current and past infection with the Hepatitis B virus (HBV).
  • Screen individuals at higher risk of HBV infection.
  • Screen individuals who show symptoms of acute hepatitis.
  • Help prevent the spread of hepatitis B to others, especially newborns or transplant patients.

How Do I Prepare for a Hepatitis B Surface Antigen (HBsAg) Test?

Do I need to fast or stop any medications before the Hepatitis B Surface Antigen (HBsAg) test?

No, fasting is not required before the Hepatitis B Surface Antigen (HBsAg) test. You can eat and drink normally before the test. However, it is essential to inform your doctor about any medications or supplements you are taking, as certain medicines may interact with test results. Your doctor will guide you if any temporary adjustments are needed before the test.

How is the Hepatitis B Surface Antigen (HBsAg) done?

  • The Hepatitis B Surface Antigen (HBsAg) is done by collecting a small amount of blood from a vein, usually in the arm. 
  • The procedure is quick, minimally invasive, and generally causes only slight discomfort.

What happens during the Hepatitis B Surface Antigen (HBsAg) test?

  • You will be seated comfortably with your arm supported on a flat surface or armrest.
  • A tourniquet (elastic band) is tied around your upper arm to make the veins more visible and easier to locate.
  • The phlebotomist identifies a suitable vein for blood collection.
  • The puncture site is then cleaned thoroughly with an alcohol swab to reduce the risk of infection.
  • A thin, sterile needle is gently inserted into the vein, and a small amount of blood is collected into a test tube.

What happens after the Hepatitis B Surface Antigen (HBsAg) test?

  • Once enough blood is collected, the tourniquet is released and the needle is removed.
  • A cotton ball or gauze is placed on the site, followed by a small bandage or dressing to stop any bleeding.
  • The blood sample is carefully labeled with your details and sent to the laboratory for analysis.
  • You can resume your daily routine after the test is done.

Is the Hepatitis B Surface Antigen (HBsAg) test painful?

No, the Hepatitis B Surface Antigen (HBsAg) test is generally safe and painless. However, you may feel slight discomfort during blood sample collection, but the chances of serious complications are extremely rare.

How Long Does the Hepatitis B Surface Antigen (HBsAg) Test Take?

The procedure is quick, simple, and safe. It requires only a small blood sample and is completed within a short duration.

When Will I Get the Results?
The availability of your test report may vary depending on your location and the laboratory where the test is conducted. Generally, the results are provided within the stipulated time frame after sample collection.

When Should I Consult a Doctor After the Test?

  • If you test positive for hepatitis B
  • If symptoms like jaundice, abdominal pain, or fatigue worsen
  • For guidance on vaccination, antiviral treatment, or liver monitoring

Are There Any Risks Associated with the Hepatitis B Surface Antigen (HBsAg) Test?

The Hepatitis B Surface Antigen (HBsAg) test is safe, with usually minimal or no risk that resolves on its own:

  • Small bruise, pinch, or slight tenderness at the puncture site
  • Occasional lightheadedness if you are sensitive to needles or blood
  • Rarely, infection or blood vessel injury
  • If you have a bleeding disorder or are taking blood thinners, please inform the phlebotomist beforehand.

Lifestyle Tips 

Lifestyle Tips for a Healthy Liver and Hepatitis B Management

🥤 Hydration: Drink plenty of water daily to help your liver detoxify and maintain overall metabolic balance.

🥗 Eat (Diet): Follow a liver-friendly diet rich in leafy greens, fruits, whole grains, and lean proteins. Avoid excessive saturated fats and processed food to support hepatitis B management.

🏃‍♀️ Activity (Exercise): Engage in regular physical activity such as walking, swimming, or light aerobics to maintain a healthy weight and promote optimal liver function.

🧘 Lifestyle (Stress): Manage stress through mindful practices like yoga, meditation, or deep-breathing exercises, as stress can negatively affect liver health and immune function.

👩‍⚕️ Talk to Your Doctor (Consultation): Regularly consult your healthcare provider to monitor hepatitis B infection, track liver function, and discuss vaccination or treatment options to prevent complications.

🍺 Habits (Smoking & Alcohol): Avoid smoking and limit alcohol consumption, as both can worsen liver inflammation and compromise hepatitis B management.

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What does Hepatitis B Surface Antigen (HBsAg) measure?

The Hepatitis B Surface Antigen (HBsAg) test detects HBsAg, a protein on the surface of the hepatitis B virus (HBV), in the blood. It is an important screening test for HBV infection. A reactive result needs follow-up with additional tests, such as anti-HBs and total anti-HBc antibodies, and can be confirmed with HBV DNA testing by PCR. This test helps identify individuals who may need medical treatment and supports measures to prevent the spread of hepatitis B. The test uses automated chemiluminescence immunoassay (CMIA/CLIA) technology, which may vary slightly across laboratories.

What Do the Results Mean?

Pathological Factors

Test Result

Interpretation

Possible Causes

Reactive

Indicates the presence of hepatitis B surface antigen in the blood

Active hepatitis B infection (acute or chronic)

Non-Reactive

No hepatitis B surface antigen detected

No active infection, or very early/resolved infection

Inconclusive

Retesting required

Sample quality issues or borderline antigen levels

Physiological Factors
 🧒 Age: Newborns and infants may have maternal HBsAg in their blood, which can affect test results.

🫄 Pregnancy: Changes in immunity and liver function during pregnancy may slightly affect HBsAg detection.

⏳ Infection Stage: Very early infection (window period) or late/chronic stages may change HBsAg levels.

Lifestyle Factors

🥗 Alcohol: Heavy drinking can affect liver function, which may indirectly influence test results.

💊 Medications: Antivirals or immunosuppressive drugs can lower viral levels, potentially altering HBsAg readings.

💉 Recent Vaccination: Hepatitis B vaccination may affect antibody levels but usually does not impact HBsAg detection.

Disclaimer: This information is for educational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider for personalized guidance.

What Do Negative Hepatitis B Surface Antigen (HBsAg) Results Mean?

A negative result usually means you do not have an active hepatitis B infection at the time of the test. It does not rule out a past infection or very early-stage infection.

What Do Positive Hepatitis B Surface Antigen (HBsAg) Results Mean?

A positive result means the hepatitis B virus is present in your blood. Early detection enables timely treatment, monitoring, and measures to prevent the spread to others.

What to Do if Your Hepatitis B Surface Antigen (HBsAg) Result Is Positive?

  • Consult your doctor for further evaluation and treatment
  • Inform close contacts so they can get vaccinated or tested
  • Follow your doctor’s schedule for liver check-ups and viral load monitoring
  • Avoid sharing personal items like razors or toothbrushes

Can Hepatitis B Surface Antigen (HBsAg) Results Be Inaccurate?

Though the test is reliable, certain factors may lead to false-positive or false-negative results:

  • Low viral load (in the early stage
  • Improper sample collection or handling
  • Interference from recent vaccination or medical conditions

FAQs related to Hepatitis B Surface Antigen (HBsAg)

The Hepatitis B Surface Antigen (HBsAg) test is needed to monitor the level of hepatitis B virus in individuals with chronic hepatitis B infection. It helps doctors assess the stage of infection, the response to antiviral therapy, and make guided treatment decisions.
The symptoms of acute hepatitis B infection may not be apparent for months after exposure to HBV. However, the most common symptoms are fatigue, muscle and joint pain, loss of appetite, dark urine, fever, belly pain, and the yellowing of the eyes and skin (jaundice).
Hepatitis B virus does not spread through food or water, by sharing utensils, breastfeeding, hugging, kissing, handholding, coughing, or sneezing.
The hepatitis B virus can be transmitted through contact with infected blood and body fluids. This can happen during unprotected sexual contact with an infected partner; from an infected mother to the unborn baby; by sharing needles, syringes, or drug preparation equipment; by sharing items such as toothbrushes or razors; due to direct contact with blood or open wounds of an infected person; and by piercing and tattooing. The infection may also spread due to poor infection control in healthcare facilities like hospitals.
Hepatitis B is infectious for as long as the virus is active in your body. If you have an acute infection, it may last from a few weeks to six months, and you are capable of transmitting the infection to healthy individuals. If you have a chronic infection, it may last a lifetime and may potentially lead to serious illnesses such as cirrhosis and liver cancer.
If your Hepatitis B Surface Antigen (HBsAg) test result is positive, your doctor may order additional tests like hepatitis B surface antibody (anti-HBs), total hepatitis B core antibody (anti-HBc), IgM antibody to hepatitis B core antigen (IgM anti-HBc), hepatitis B “e” antigen (HBeAg), hepatitis B “e” antibody (HBeAb or anti-HBe), hepatitis B viral DNA, and liver function test.
Hepatitis B can be best prevented by vaccination. The hepatitis B vaccine is safe and effective and should be given in three doses for full protection (at 0, 1, and 6 months).
The types of hepatitis virus include hepatitis A, hepatitis B, hepatitis C, hepatitis D, and hepatitis E.

Hepatitis B Surface Antigen (HBsAg) test price for other cities

Price inBangaloreRs. 499
Price inNew DelhiRs. 499
Price inPuneRs. 449
Price inGurgaonRs. 499
Price inMumbaiRs. 499

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Hepatitis B Surface Antigen (HBsAg)