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LFT and KFT (Liver Function Test & Kidney Function Test)

LFT and KFT (Liver Function Test & Kidney Function Test) Includes 17 testsView All
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Understanding LFT and KFT (Liver Function Test & Kidney Function Test)

What is LFT and KFT (Liver Function Test & Kidney Function Test)?

This package comprises a liver function test (LFT) and a kidney function test (KFT) with electrolytes that help evaluate liver and kidney functions and detect any disorders associated with these organs. In addition, this package also assesses the pH and water balance in the body.

The liver is the largest organ in our body and performs various vital functions, including the metabolism of nutrients like fats, proteins, carbohydrates, and certain medicines. It also cleanses the blood (a process called detoxification) by converting toxins into waste products. On the other hand, the kidneys play a vital role in removing waste, toxins, and extra water from the body. They maintain a healthy balance of water, salts, and minerals like calcium, sodium, potassium, and phosphorus. Additionally, the kidneys control the blood pressure and the body’s pH balance, produce hormones for RBC production, and promote bone health. Together, both the liver and kidneys play essential roles in maintaining overall health.

An LFT and KFT (Liver Function Test & Kidney Function Test) plays a crucial role in screening and diagnosing liver problems, like fatty liver disease, cirrhosis, jaundice & hepatitis, and kidney diseases, like kidney stones, urinary tract infections, and gout. This test also helps the physician to initiate appropriate treatment timely and avoid further complications. This package can also effectively monitor ongoing treatment for existing liver or kidney issues. Usually, no special preparation is required for this test; eat and drink as per your daily routine. 

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. Narrate your complete medical history to help them correlate your clinical and laboratory findings. The test results will help the doctor determine your medical condition and formulate your treatment plan.

What is LFT and KFT (Liver Function Test & Kidney Function Test) used for?

An LFT and KFT (Liver Function Test & Kidney Function Test) is done:

  • As part of routine health checkups.
  • To diagnose any disease affecting the liver or kidneys, especially if you have risk factors, such as obesity, diabetes, high blood pressure, or a family history of liver or kidney disease.
  • To monitor an existing liver or kidney disease and ongoing treatment response.
  • To monitor the effects of certain medications that affect your liver or kidney function.
  • To monitor for alcohol abuse.

What does LFT and KFT (Liver Function Test & Kidney Function Test) measure?

Contains 17 tests

An LFT and KFT (Liver Function Test & Kidney Function Test) measures the components contributing to liver and kidney health. LFT is a group of tests that evaluates the levels of enzymes, proteins, and bilirubin produced by the liver. These components help to understand overall liver health and detect possible liver diseases. KFT with electrolytes evaluates the health of your kidneys. This test checks various parameters, such as creatinine, urea, uric acid, and electrolytes (sodium, potassium, and chlorine). It also helps diagnose possible kidney disorders, such as inflammation, infection, or functional damage in the kidneys.

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LFT (Liver Function Test)

An LFT (Liver Function Test) helps determine the health of your liver by measuring various components like enzymes, proteins, and bilirubin. These components help detect inflammation, infection, diseases, etc., of the liver and monitor the damage due to liver-related issues.

Know more about LFT (Liver Function Test)

  • Bilirubin Indirect

  • A Bilirubin Indirect test measures the amount of indirect or unconjugated bilirubin in your body. Bilirubin is a yellowish byproduct primarily produced when your body breaks down aged red blood cells (RBCs). When RBCs finish their lifespan of 120 days, they break down and pass to your liver. Indirect bilirubin, a form of bilirubin that is unconjugated (not soluble in water), is bound to the protein albumin that helps transport it to the liver. When the liver processes the bilirubin, it unbinds from the albumin and binds to a sugar molecule, making it water-soluble. This water-soluble bilirubin is mixed with bile, excreted in the bile ducts, and stored in your gallbladder. Finally, bile is released into the small intestine to help digest fat and is eventually excreted with your stool as a waste product.

  • Bilirubin Direct

  • A Bilirubin Direct test measures the amount of direct or conjugated bilirubin present in your body. Bilirubin is a yellowish byproduct primarily produced when the body breaks down aged RBCs. When the RBCs finish their lifespan of 120 days, they break down and pass to the liver. In the liver, direct bilirubin–a form of bilirubin conjugated with glucuronic acid (sugar)–is processed, mixed with bile, and then excreted in the bile ducts and stored in your gallbladder. Finally, the bile is released into the small intestine where it is further broken down and helps digest fat. It is eventually excreted within your stool as a waste product.

    Elevated levels of bilirubin can be indicative of various liver or bile duct issues. Additionally, higher bilirubin levels might result from an increased breakdown of red blood cells in the body.

  • Gamma Glutamyl Transferase

  • Gamma-Glutamyl Transferase (GGT) is an enzyme found in various organs, with the highest concentration in the liver. Usually, this enzyme is present in low levels in the blood. However, when there is liver damage or disease, GGT is released into the bloodstream, causing an increase in GGT levels. In addition to the liver, GGT can also be elevated in conditions affecting the bile ducts or the pancreas. It is usually, the first liver enzyme to rise in the blood when there is any damage or obstruction in the bile duct, making it one of the most sensitive liver enzyme tests for detecting bile duct problems.

  • Bilirubin Total

  • A Bilirubin Total examination quantifies the levels of total bilirubin in the body, encompassing both indirect (unconjugated) and direct (conjugated) bilirubin. Bilirubin, a yellowish waste substance, is primarily generated during the breakdown of aging red blood cells (RBCs) in the body. After their typical lifespan of 120 days, RBCs disintegrate in the liver, leading to the production of a substantial amount of bilirubin. It is crucial for this bilirubin to be eliminated from the body.

  • SGPT

  • An SGPT test measures the amount of ALT or SGPT enzyme in your blood. ALT is most abundantly found in the liver, but it is also present in smaller amounts in other organs like the kidneys, heart, and muscles. Its primary function is to convert food into energy. It also speeds up chemical reactions in the body. These chemical reactions include the production of bile and substances that help your blood clot, break down food and toxins, and fight off an infection.

    Elevated levels of ALT in the blood may indicate liver damage or injury. When the liver cells are damaged, they release ALT into the bloodstream, causing an increase in ALT levels. Therefore, the SGPT/ALT test is primarily used to assess the health of the liver and to detect liver-related problems such as hepatitis, fatty liver disease, cirrhosis, or other liver disorders.

  • Alkaline Phosphatase (ALP)

  • An Alkaline Phosphatase (ALP) test measures the quantity of ALP enzyme present throughout the body. The main sources of this enzyme are the liver and bones. It exists in different forms depending on where it originates, such as liver ALP, bone ALP, and intestinal ALP. In the liver, it is found on the edges of the cells that join together to form bile ducts. 

    ALP levels can be increased during pregnancy as it is found in the placenta of pregnant women. It is also higher in children because their bones are in the growth phase. ALP is often high during growth spurts (a short period when an individual experiences quick physical growth in height and body weight).

  • SGOT

  • An SGOT test measures the levels of serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase (AST), an enzyme produced by the liver. SGOT is present in most body cells, most abundantly in the liver and heart. The primary function of this enzyme is to convert food into glycogen (a form of glucose), which is stored in the cells, primarily the liver. The body uses this glycogen to generate energy for various body functions.

  • Protein Total, Serum

  • A Protein Total, Serum test measures the amount of proteins in the body. Proteins are known as the building blocks of all cells and tissues. They play a crucial role in the growth and development of most of your organs and in making enzymes and hormones. There are two types of proteins found in the body, namely albumin and globulin. About 60% of the total protein is made up of albumin, which is produced by the liver. It helps to carry small molecules such as hormones, minerals, and medicines throughout the body. It also serves as a source of amino acids for tissue metabolism. On the other hand, globulin is a group of proteins that are made by the liver and the immune system. They play an important role in liver functioning, blood clotting, and fighting off infections.

    This further contains

    • Serum Albumin
    • Protein Total
    • Globulin, Serum
    • Albumin/Globulin Ratio, Serum
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KFT with Electrolytes (Kidney Function Test with Electrolytes)

A KFT with Electrolytes (Kidney Function Test with Electrolytes) test determines the health of your kidneys. It evaluates parameters such as creatinine, blood urea nitrogen (BUN), uric acid, and electrolytes (sodium, potassium, and chloride). This test also helps diagnose possible kidney disorders like inflammation, infection, or functional damage.

Know more about KFT with Electrolytes (Kidney Function Test with Electrolytes)

  • Serum Creatinine

  • A Serum Creatinine test measures the level of creatinine in the blood. Creatinine is a byproduct of muscles’ wear and tear during energy production. The kidneys remove it from the body by filtering it from the blood and releasing it into the urine. Therefore, blood creatinine levels indicate how well the kidneys are functioning in filtering and removing waste products from the blood. Generally, higher creatinine levels in the blood may indicate reduced kidney function, while lower levels may suggest decreased muscle mass.

  • Potassium

  • A Potassium test measures the levels of potassium in your body. Potassium is one of the key electrolytes that helps in the functioning of the kidneys, heart, nerves, and muscles. It also balances the effect of sodium and helps keep your blood pressure normal. The body absorbs the required amount of potassium from the dietary sources and eliminates the remaining quantity through urine. Potassium level is typically maintained by the hormone aldosterone. Aldosterone acts on the nephrons present in the kidneys and activates the sodium-potassium pump that helps the body reabsorb sodium and excrete potassium. This aids in maintaining a regular and steady potassium level in the blood.

  • Uric Acid

  • A Uric Acid test determines the level of uric acid in your body. Uric acid is a nitrogenous compound produced by the metabolic breakdown of purine. Purines are present as nitrogenous bases in the DNA and are also found in food like red meat and seafood.

    Most uric acid dissolves in the blood and goes into your kidneys. From there, it passes through your body via the urine. Decreased elimination of uric acid is often a result of impaired kidney function due to kidney disease. In many cases, the exact cause of excess uric acid is unknown. Doctors seldom need to test for low levels of uric acid.

  • Chloride

  • A Chloride test measures the amount of chloride in your body. Chloride is present in all body fluids and is found in the highest concentration in the blood and extracellular fluid (fluid present outside the cells). The body gets most of the chloride through dietary salt (sodium chloride or NaCl) and a small amount through other food items. The required amount of chloride is absorbed in the body and the excess amount is excreted by the kidneys through urine. When the chloride is combined with sodium it is mostly found in nature as salt. Chloride generally increases or decreases in direct relationship to sodium but may also change without any changes in sodium levels when there are problems with the body's pH. Usually, the normal blood chloride level remains steady with a slight fall after meals (because the stomach produces hydrochloric acid using chloride from the blood after we eat food).

  • Sodium

  • A Sodium test is used to measure the amount of sodium in your body. Sodium is present in all body fluids and is found in the highest concentration in the extracellular fluid. The body absorbs the required amount of sodium through dietary salts and the remaining is eliminated through the kidneys. The body keeps your blood sodium within a normal and steady range by following three mechanisms:

    • By producing hormones that control the elimination of sodium through urine, such as natriuretic peptides and aldosterone.

    • By producing hormones that prevent water loss, such as antidiuretic hormone (ADH) or vasopressin.

    • By controlling thirst (an increase in blood sodium level can make you thirsty and cause you to drink water, returning your sodium to normal).

    These mechanisms regulate the amount of water and sodium in the body and control blood pressure by keeping the amount of water in check. When the level of sodium in the blood changes, the water content in your body changes. These changes can be associated with dehydration, edema, and change in blood pressure.

  • Blood Urea Nitrogen (BUN)

  • A Blood Urea Nitrogen (BUN) test measures the levels of urea nitrogen in the blood. Blood urea is a waste product that is formed in the liver when you eat food and the protein is metabolized into amino acids. This process leads to the production of ammonia that is further converted into urea. Both ammonia and urea are nitrogenous compounds. Your liver releases urea into the blood which is then carried out to the kidneys. In the kidneys, urea is filtered from the blood and flushed out of the body via urine. This is a continuous process, so a small amount of urea nitrogen always remains in the blood.

    In the case of a kidney or liver disease, there is a change in the amount of urea present in the blood. If your liver produces urea in an increased amount or if there is any problem in kidney functioning, there might be difficulty in filtering out the waste products from the blood, which can result in increased urea levels in the blood.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about LFT and KFT (Liver Function Test & Kidney Function Test)

Frequently Asked Questions about LFT and KFT (Liver Function Test & Kidney Function Test)

Q. What is the purpose of an LFT and KFT package?

An LFT and KFT package is done to check how well your liver and kidneys are working. This package is also used to detect diseases related to the liver and kidneys to avoid further complications.

Q. What components are measured by an LFT and KFT package?

An LFT and KFT package measures the components relevant to the health and proper functioning of the liver and kidneys. LFT includes components such as enzymes like aspartate aminotransaminase (AST), also known as serum glutamic-oxaloacetic transaminase (SGOT), alanine aminotransaminase (ALT), also known as serum glutamic-pyruvic transaminase (SGPT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT); total-protein like albumin and globulin; and total-bilirubin both direct and indirect. Components included in KFT with electrolytes are creatinine, uric acid, blood urea nitrogen (BUN), and electrolytes like sodium, potassium, and chloride.

Q. What are the common signs and symptoms of kidney problems?

Urinating more or less, back pain, belly pain, muscle cramps, loss of appetite, fatigue, and weakness are some of the common signs and symptoms of kidney problems.

Q. What if my test results show high SGOT and SGPT levels?

SGOT and SGPT enzymes are typically found within liver cells, and elevated levels can be a sign of liver damage or dysfunction. Some of the possible reasons for high SGOT and SGPT levels are liver diseases like hepatitis, cirrhosis, fatty or alcoholic liver diseases; excessive alcohol consumption; autoimmune disorders like autoimmune hepatitis, non-alcoholic fatty liver disease; viral infections like hepatitis B or C; and medications like ibuprofen, diclofenac, naproxen, etc. If your test results show high SGOT and SGPT levels, immediately consult your doctor.

Q. How can I reduce SGOT and SGPT levels quickly and naturally?

Reducing SGOT (Serum Glutamic Oxaloacetic Transaminase) and SGPT (Serum Glutamic Pyruvic Transaminase) levels quickly and naturally primarily depends on addressing the underlying cause of elevated liver enzymes. If the elevation is due to a specific condition or lifestyle factor, managing that condition or making healthy choices can help improve your liver health. Here are some general tips to consider: Consult a healthcare provider, manage underlying health conditions, focus on lifestyle changes like limiting alcohol consumption, maintaining a healthy weight, consuming a nutrient-rich diet, staying hydrated, etc., exercise regularly, reduce stress, and avoid taking medications without a prescription.

Q. What can cause a fatty liver?

Consuming excess calories can cause fat to build up in the liver. When the liver does not process and break down fats, it can lead to the accumulation of fats in the liver (fatty liver). You may also develop fatty liver in certain other conditions such as obesity, diabetes or high triglycerides, and too much alcohol use.

Q. How can I keep my liver healthy?

You can keep your liver healthy by adopting some lifestyle changes such as limiting alcohol intake, exercising regularly to maintain a healthy body weight; and including foods such as berries, broccoli, cabbage, cauliflower, beans, whole grains, and nuts in your daily diet.

Q. What are the early signs of an unhealthy liver?

Yellowing of skin and eyes, belly pain, swelling in legs and ankles, weakness, fatigue, nausea, itchy skin, dark urine, and pale stools are some of the early signs of an unhealthy liver.

Q. What is chronic kidney disease (CKD)?

Chronic kidney disease (CKD) or chronic kidney failure is a medical condition characterized by the steady and progressive loss of kidney function, often leading to complete kidney failure if left untreated.

Q. How can I improve my kidney health?

Adopting healthy eating habits, maintaining an active lifestyle, limiting alcohol intake, and drinking plenty of water to stay hydrated can help improve your kidney health.

Q. What causes high levels of bilirubin?

High levels of bilirubin in the blood, a condition known as hyperbilirubinemia, can be caused by various factors, some of which are related to liver function, while others may be due to issues with the breakdown of red blood cells. Some of the common causes of high bilirubin levels are hemolysis; liver disorders like cirrhosis, hepatitis, obstruction of the bile ducts; biliary tract disorder; newborn jaundice; alcohol abuse; infections; and medications like antibiotics or chemotherapy drugs.

Q. What levels of bilirubin are dangerous in newborns?

According to the American Academy of Pediatrics (AAP), bilirubin levels up to 17-18 mg/dl can be deemed normal for healthy full-term babies. It is critical for healthcare workers to monitor infant bilirubin levels to reduce the chances of newborn jaundice.

Q. What does a BUN test measure in LFT and KFT package?

A BUN test is a blood test used to assess kidney function and the body's waste product removal process. It measures the concentration of urea nitrogen in the blood. Urea is a waste product generated when the body breaks down proteins from the food we eat and from the normal breakdown of body tissues. Healthy kidneys filter urea and other waste products from the blood and excrete them in the urine. Elevated BUN levels can be an indication of impaired kidney function.
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LFT and KFT (Liver Function Test & Kidney Function Test) test price for other cities

Price inBangaloreRs. 689
Price inGurgaonRs. 609
Price inMumbaiRs. 609
Price inKolkataRs. 539
Price inNoidaRs. 1120
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  3. Common Liver Tests [Internet]. Johns Hopkins Medicine; [Accessed 24 Jan. 2023]. Available from: https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/common-liver-testsExternal Link
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  5. Know Your Kidney Numbers: Two Simple Tests [Internet]. NY: National Kidney Foundation; [Accessed 10 Apr. 2023]. Available from: https://www.kidney.org/atoz/content/know-your-kidney-numbers-two-simple-tests#:~:text=CKD%20is%20evaluated%20using%20twoExternal Link
  6. Kidney Testing: Everything You Need to Know [Internet]. CDC; 24 Mar. 2022 [Accessed 10 Apr. 2023]. Available from: https://www.cdc.gov/kidneydisease/publications-resources/kidney-tests.htmlExternal Link
  7. Gounden V, Bhatt H, Jialal I. Renal Function Tests. In: StatPearls [Internet]. Treasure Island, Florida: StatPearls Publishing; Jan. 2023 [Accessed 10 Apr. 2023]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507821/External Link


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