Alpha 1 Antitrypsin

Alpha-1 antitrypsin (AAT) is a protein produced mainly in the liver and released into the blood. Its main role is to protect lung tissue from damage caused by enzymes such as neutrophil elastase, which are released during inflammation or infection. Without sufficient levels of AAT, these enzymes can break down normal lung tissue, leading to chronic obstructive pulmonary disease (COPD), emphysema, or bronchiectasis. In some cases, abnormal AAT protein may accumulate in the liver, causing liver inflammation, cirrhosis, or even liver cancer. The Alpha 1 Antitrypsin test assesses AAT levels in the blood and plays a key role in preventing severe lung and liver damage through early diagnosis and treatment.

The Alpha 1 Antitrypsin test is recommended when there is suspicion of abnormal alpha-1 antitrypsin levels or related lung and liver conditions. It is particularly advised for individuals with symptoms such as shortness of breath, chronic obstructive pulmonary disease (COPD), or unexplained liver disease. Doctors may also suggest this test if there is a family history of AAT deficiency, emphysema, or liver disease. It may also be recommended in cases where emphysema develops before the age of 45, occurs in non-smokers, or presents with unusual patterns of lung involvement.

No special preparation is required for the Alpha 1 Antitrypsin test. Inform a doctor about all the medications, supplements, and underlying illnesses, as all these factors may affect the test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.