What is NT-Pro BNP?
NT-Pro BNP test is used to measure the amount of BNP (B-Type Natriuretic peptide) and NT-Pro BNP (N-Terminal-Pro) in the blood. These molecules are released into the blood stream in response to any stress encountered by the heart. Elevated level of these molecules is an indicator of excessive pressure on heart, heart faliure, or other acute heart conditions.
This test is recommended generally after a heart attack or to those undergoing any heart disease treatment.
A normal value of NT-Pro-BNP should be under 100pg/mL. Any value higher than this is considered fatal and an immediate medical intervention is mandatory.
Why is NT-Pro BNP done?
The NT-Pro BNP test is done to help in the detection, diagnosis, and evaluation of the severity of congestive heart failure (CHF).
What does NT-Pro BNP Measure?
The NT-Pro BNP Test measures the levels of the protein BNP in blood. The NT-Pro BNP (N-terminal pro b-type natriuretic peptide) is a substance secreted by the left ventricle of the heart due to the stretching of the heart chamber while pumping blood. It helps in the relaxation of blood vessels for smooth blood flow. The heart continuously secretes a precursor substance called pro-BNP which is converted to BNP to maintain a low constant level in blood. In case of congestive heart failure, the heart works harder to pump blood causing extra pressure in the heart muscles. This leads to an increase in the production of BNP to help stimulate the blood vessels to relax and reduce the pressure on the heart. This increased production of BNP could be due to other conditions which affect the circulatory system like blockages in blood vessels.
The B-Type Natriuretic Peptide was initially named the Brain Type Natriuretic Peptide since it was first detected in the brain tissues. Later, it was renamed to B-Type to distinguish it from Atrial or A-Type Natriuretic Peptide (ANP), which is another substance with similar function also produced in the heart.
Interpreting NT-Pro BNP results
AGE IN YEARS
97.5th PERCENTILE IN pg/mL
Reference range may vary from lab to lab*
In case of congestive failure in first hour or in case of ventricular inflow obstruction, there is lack of rise of N-terminal pro-BNP levels.