Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
City Price Info
Home Collection
References
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NT-Pro BNP

Also known as Brain natriuretic peptide, N terminal pro B type natriuretic peptide, Natriuretic peptides
30003349 10% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding NT-Pro BNP


What is NT-Pro BNP?

The NT-proBNP (N-terminal pro-B-type natriuretic peptide) test is used to measure the levels of NT-proBNP in the blood. NT-proBNP is a hormone produced by the heart in response to increased pressure or stress on the heart muscle. It helps diagnose and manage heart-related conditions, such as heart failure.

Heart failure occurs when the heart cannot pump blood effectively, leading to symptoms such as shortness of breath, fatigue, swelling in ankles, feet, and legs, and frequent urination. An NT-Pro BNP test helps confirm the diagnosis of heart failure, assesses its severity, monitors its progression, and differentiates it from other conditions with similar symptoms.

An NT-Pro BNP test is often performed alongside other cardiac tests, such as an electrocardiogram (ECG) or echocardiogram, to comprehensively evaluate heart health. Your doctor may advise this test if you experience symptoms of heart failure or if you have risk factors for heart failure such as high blood pressure, diabetes, any previous history or family history of heart disease, etc.

Fasting is not required for an NT-Pro BNP test. You can eat or drink normally, as per your daily routine. This test is generally safe and well-tolerated. Minimal discomfort or bruising may rarely occur at the site where the blood sample is drawn, but serious complications are rare. Inform your doctor about all the medicines, including herbal or over-the-counter products, vitamins, and supplements you might be taking.

Test results may vary between laboratories. A higher-than-normal NT-proBNP level may suggest heart failure or other cardiac conditions. Talk to your doctor about your specific test results. The results will help them assess your cardiac health, monitor disease progression, and determine the most appropriate interventions to manage your heart health better.

What is NT-Pro BNP used for?

An NT-Pro BNP is done:

  • To diagnose congestive heart failure (CHF) and assess its severity.

  • If an individual experiences signs and symptoms of heart disease such as cough, breathlessness, extreme fatigue, swelling in ankles, feet, legs, and veins in the neck, abdominal pain, or frequent urination.

  • To monitor the response to heart failure treatment.

  • To differentiate heart failure from other conditions with similar symptoms.

  • To assess the risk of cardiovascular diseases in individuals with risk factors such as high blood pressure, diabetes, any previous history or family history of heart disease, etc.

What does NT-Pro BNP measure?

An NT-Pro BNP test measures the concentration of NT-proBNP (N-terminal pro-B-type natriuretic peptide) in the blood. It is a cardiac hormone secreted from the left ventricles (the organ's main pumping chamber) and helps to regulate blood volume. When heart failure develops or worsens, the heart muscle cells produce NT-Pro BNP, which is released into the bloodstream. It helps alleviate the condition by relaxing the blood vessels, reducing fluid volume, and reducing the heart's workload.

NT-Pro BNP concentration increases in heart failure and other diseases that affect the heart and circulatory system. Measuring the levels of NT-Pro BNP can provide insight into your heart’s current health and functioning.

Interpreting NT-Pro BNP results


Interpretations

 

AGE IN YEARS

97.5th PERCENTILE IN pg/mL

1-3

320

4-6

190

7-9

145

10

112

11

317

12

186

13

370

14

363

15

217

16

206

17

135

18-44

115

45-54

172

55-64

263

65-74

349

>=75

738

 

Reference range may vary from lab to lab*

 

In case of congestive failure in first hour or in case of ventricular inflow obstruction, there is lack of rise of N-terminal pro-BNP levels.

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about NT-Pro BNP


Frequently Asked Questions about NT-Pro BNP

Q. In what conditions can levels of NT-Pro BNP increase?

The levels of NT-Pro BNP can increase in conditions such as heart failure, asymptomatic left ventricular dysfunction, arterial and pulmonary hypertension, cardiac hypertrophy, valvular heart disease, arrhythmia, and acute coronary syndrome. Along with that, an increased amount of NT-Pro BNP is seen in individuals with acute and chronic kidney failure, liver cirrhosis, hyperaldosteronism, diabetes mellitus, and Cushing’s syndrome.

Q. Can exercise affect the NT-Pro BNP levels?

Research and studies show that vigorous exercise can temporarily increase your NT-Pro BNP levels. Tell your doctor if you have done intense physical activity before your test.

Q. How frequently should you take this test?

An NT-Pro BNP test is not a routine test. The frequency of this test is decided by the doctor or healthcare professional based on an individual's condition. This test is advised to rule out or diagnose congestive heart failure (CHF) and to assess the effectiveness of treatment in patients with CHF.

Q. How is a NT-Pro BNP performed?

A phlebotomist (a trained professional to perform blood draws) will clean your skin using an antiseptic alcohol cotton swab or wipe and take a blood sample from your vein using a needle. The blood sample will be stored safely and transported to the laboratory for analysis.

Q. What other tests can be prescribed by your doctor if the results of an NT-Pro BNP test are abnormal?

The doctor may suggest other tests if the results of the (test_name} test are abnormal. These tests include an ANP test, chest X-ray, electrocardiogram, and echocardiogram.

Q. What are the common symptoms of heart failure?

Heart failure can be indicated by symptoms such as difficulty breathing, shortness of breath, feeling tired, and swelling (edema) in the feet, ankles, legs, and abdomen.

Q. What is congestive heart failure, and what are its possible causes?

Congestive heart failure is a progressive or long-term condition in which the heart is not able to pump blood well enough to give your body a regular blood supply. Blood and fluids collect in your lungs and legs over time. Congestive heart failure can be caused by several factors, such as high blood pressure (hypertension) and coronary artery diseases, where cholesterol deposition occurs on the inner wall of the blood vessels, causing a blockage in the blood supply.

Q. Can heart failure be cured?

There is no cure for heart failure. However, treatment can help you live a longer, more active life with fewer symptoms. Treatment depends on the type of heart failure you have and how severe it is. Consult a doctor to get the best possible advice, depending on your condition.
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NT-Pro BNP test price for other cities


Price inMumbaiRs. 3000
Price inBangaloreRs. 3000
Price inGurgaonRs. 3000
Price inKolkataRs. 3000
Price inPuneRs. 3000
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References

  1. Heart Failure [Internet]. NHS; 19 May 2022 [Accessed 16 Mar. 2023]. Available from: [Accessed 18 Oct. 2023]. Available from: https://www.nhs.uk/conditions/heart-failure/ External Link
  2. BNP (Blood) [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 18 Oct. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=bnp_blood External Link
  3. Latini R, Masson S. NT-proBNP: A Guide to Improve the Management of Patients with Heart Failure. EJIFCC. 2013 Feb 21;24(3):78-84. PMID: 27683441; PMCID: PMC4975180. [Accessed 18 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975180/ External Link
  4. Bui AL, Horwich TB, Fonarow GC. Epidemiology and risk profile of heart failure. Nat Rev Cardiol. 2011 Jan;8(1):30-41. [Accessed 18 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033496/#:~:text=A%20number%20of%20risk%20factors,as%20well%20as%20its%20severity. External Link
  5. Hamasaki H. The Effects of Exercise on Natriuretic Peptides in Individuals without Heart Failure. Sports (Basel). 2016 May 31;4(2):32. [Accessed 18 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968914/ External Link
  6. Heart Failure-Treatment [Internet]. NIH; 24 Mar. 2022. [Accessed 18 Oct. 2023]. Available from: https://www.nhlbi.nih.gov/health/heart-failure/treatment#:~:text=Heart%20failure%20has%20no%20cure,and%20how%20serious%20it%20is. External Link
  7. Heart Failure- Causes and Risk Factors [Internet]. NIH; 24 Mar. 2022. [Accessed 18 Oct. 2023]. Available from: https://www.nhlbi.nih.gov/health/heart-failure/causes#:~:text=Unhealthy%20lifestyle%20habits%2C%20such%20as,CoV%2D2%20raise%20your%20risk. External Link
  8. Lifestyle Changes for Heart Failure [Internet]. Dallas, Texas: American Heart Association; 10 Jul. 2023 [Accessed 18 Oct. 2023]. Available from: https://www.heart.org/en/health-topics/heart-failure/treatment-options-for-heart-failure/lifestyle-changes-for-heart-failure External Link
  9. Cao Z, Jia Y, Zhu B. BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine. Int J Mol Sci. 2019 Apr 12;20(8):1820. [Accessed 18 Oct. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6515513/ External Link

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