
SGPT & SGOT










The SGPT & SGOT test measures the levels of two important liver enzymes: serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvic transaminase (SGPT) in the blood. These tests are commonly done to assess liver function, diagnose liver disorders, and monitor liver health.












Understanding SGPT & SGOT
SGOT, also known as AST or Aspartate Aminotransferase, and SGPT, or ALT or Alanine Aminotransferase, are two enzymes predominantly found in the liver that play key roles in amino acid metabolism. Both enzymes are crucial for various metabolic processes, including the synthesis and breakdown of proteins. These enzymes are released into the bloodstream when liver cells are injured or destroyed.
Doctors may advise the SGOT and SGPT test when an individual exhibits symptoms suggestive of liver dysfunction, including jaundice (yellowing of the skin or eyes), abdominal pain, dark urine, pale stool, fatigue, and unexplained weight loss. These tests are also done as a part of a standard liver function test (LFT), especially in individuals with risk factors such as excessive alcohol consumption, obesity, diabetes, or a history of liver disease. Additionally, these tests can be used to assess the effectiveness of treatments for liver-related conditions.
No special preparation is required before undergoing SGOT and SGPT tests. However, following your doctor’s instructions and informing them of any medications or supplements you are taking is advisable, as these can impact test results.
Lab test results may vary across laboratories. Abnormal test results require expert interpretation; therefore, do not self-medicate at home solely based on these results, and consult your doctor for a proper understanding of the test results. Based on the results, your doctor will assess your medical condition, suggest lifestyle changes like diet and exercise, and decide if medication is needed to manage your condition.
What does SGPT & SGOT measure?
Contains 2 testsThe SGPT & SGOT test measures the levels of two key liver enzymes in the blood: SGOT (serum glutamic-oxaloacetic transaminase) and SGPT (serum glutamic-pyruvic transaminase). These enzymes are produced in the liver and are essential for metabolic processes involving amino acids. Elevated levels of SGOT and SGPT can indicate liver damage or inflammation, providing valuable information for diagnosing liver conditions and monitoring liver health. By assessing these enzyme levels, doctors can gain insights into liver function and guide appropriate treatment or management strategies.
An SGPT (Alanine Transaminase) test measures the level of alanine transaminase (ALT), also known as SGPT, in the blood. ALT is found predominantly in the liver and in smaller amounts in other tissues, including the kidneys, heart, and skeletal muscles. It is involved in amino-acid metabolism, particularly in the conversion of alanine and other metabolites during normal cellular processes.
Elevated ALT levels in the blood may indicate liver cell injury or inflammation. When liver cells are damaged, ALT can be released into the bloodstream, causing its level to increase. Therefore, the SGPT/ALT test is commonly used to assess possible liver injury and may be elevated in conditions such as hepatitis, fatty liver disease, cirrhosis, and other liver disorders. However, an elevated ALT level does not by itself establish a specific diagnosis or indicate the extent of liver damage.
Know more about SGPT (Alanine Transaminase)
An SGOT (Aspartate Aminotransferase) test measures the level of serum glutamic-oxaloacetic transaminase (SGOT), also known as aspartate aminotransferase (AST), in the blood. AST is an enzyme involved in amino-acid metabolism and is found in several body tissues, particularly the liver, heart and skeletal muscles. When cells in these tissues are damaged, AST can be released into the bloodstream, causing its levels to rise. Therefore, this test helps detect possible tissue injury, including liver damage, and is often performed as part of a liver function test panel.
Know more about SGOT (Aspartate Aminotransferase)





FAQs related to SGPT & SGOT
- Aspartate Transaminase [Internet]. ScienceDirect; [Accessed 27 Aug. 2024]. Available from:
- Aspartate Transaminase[ Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 27 Aug. 2024]. Available from:
- Moriles KE, Azer SA. Alanine Amino Transferase [Internet]. Treasure Island, Florida: StatPearls Publishing; 10 Dec. 2022 [Accessed 27 Aug. 2024] Available from:
- ALT [Internet]. Rochester: NY: University of Rochester Medical Center; [Accessed 27 Aug. 2024] Available from:
- Viral Hepatitis and Liver Disease [Internet]. Washington, DC: US Department of Veterans Affairs; [Accessed 27 Aug. 2024] Available from:
- Alanine Aminotransferase [Internet]. ScienceDirect; [Accessed 27 Aug. 2024] Available from:
Other tests
- LFT (Liver Function Test)
- LFT and KFT (Liver Function Test & Kidney Function Test),
- LFT and KFT (Liver Function Test & Kidney Function Test)
- Hepatitis B Surface Antigen (HBsAg), Rapid Screening Test
- Viral Marker Screening (HIV, HBsAg, Anti-HCV)
- Hepatitis C Antibody (HCV), Rapid Screening Test
- Serum Electrolytes
- Sodium
- SGPT & SGOT,
- SGPT (Alanine Transaminase)
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)





