SGPT & SGOT

SGOT, also known as AST or Aspartate Aminotransferase, and SGPT, or ALT or Alanine Aminotransferase, are two enzymes predominantly found in the liver that play key roles in amino acid metabolism. Both enzymes are crucial for various metabolic processes, including the synthesis and breakdown of proteins. These enzymes are released into the bloodstream when liver cells are injured or destroyed. 

Doctors may advise the SGOT and SGPT test when an individual exhibits symptoms suggestive of liver dysfunction, including jaundice (yellowing of the skin or eyes), abdominal pain, dark urine, pale stool, fatigue, and unexplained weight loss. These tests are also done as a part of a standard liver function test (LFT), especially in individuals with risk factors such as excessive alcohol consumption, obesity, diabetes, or a history of liver disease. Additionally, these tests can be used to assess the effectiveness of treatments for liver-related conditions.

No special preparation is required before undergoing SGOT and SGPT tests. However, following your doctor’s instructions and informing them of any medications or supplements you are taking is advisable, as these can impact test results. 

Lab test results may vary across laboratories. Abnormal test results require expert interpretation; therefore, do not self-medicate at home solely based on these results, and consult your doctor for a proper understanding of the test results. Based on the results, your doctor will assess your medical condition, suggest lifestyle changes like diet and exercise, and decide if medication is needed to manage your condition.