


Zisavel 200 Injection
Isavuconazole (200mg)
Authenticity Assured
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Stored between 2-8°C
Zisavel 200 Injection is an antifungal medicine. It is used to treat certain types of fungal infections called invasive aspergillosis and invasive mucormycosis in patients 18 years of age and older. It works by stopping the growth of fungi in the body.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Oct 2026 | 01:02 AM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 12 Oct 2026 | 01:02 AM (IST)
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General Information
Contains
Isavuconazole (200mg)
Marketer
BDR Pharmaceuticals Internationals Pvt
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English



Product introduction
Zisavel 200 Injection is given by a doctor or a nurse. Do not self-administer this medicine at home. The dose and duration of the treatment will depend on the severity of your condition. Continue to get the injection until you finish your complete course, even if your symptoms disappear after a few days. Stopping it too early may result in a return of the infection.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, increased liver enzymes, decreased potassium level in blood, constipation, breathlessness, cough, peripheral edema, and back pain. If any of these side effects persist or worsen, consult with your doctor. In rare cases, Zisavel 200 Injection may cause serious liver disease. Get medical help right away if you have any symptoms of liver damage, including persistent nausea/vomiting, loss of appetite, stomach pain, yellowing eyes/skin, or dark urine.
Before getting the injection, tell your doctor if you have any known history of allergy to this medicine. Let your doctor also if you have any preexisting medical conditions, especially liver disease and heart problems. This medicine may make you dizzy. Avoid consumption of alcohol while on treatment with this medicine. Additionally, do not drive, use machinery, or do anything that needs alertness until you know how the medicine works. Before taking this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause harmful effects to the developing baby.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, increased liver enzymes, decreased potassium level in blood, constipation, breathlessness, cough, peripheral edema, and back pain. If any of these side effects persist or worsen, consult with your doctor. In rare cases, Zisavel 200 Injection may cause serious liver disease. Get medical help right away if you have any symptoms of liver damage, including persistent nausea/vomiting, loss of appetite, stomach pain, yellowing eyes/skin, or dark urine.
Before getting the injection, tell your doctor if you have any known history of allergy to this medicine. Let your doctor also if you have any preexisting medical conditions, especially liver disease and heart problems. This medicine may make you dizzy. Avoid consumption of alcohol while on treatment with this medicine. Additionally, do not drive, use machinery, or do anything that needs alertness until you know how the medicine works. Before taking this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause harmful effects to the developing baby.
Uses of Zisavel Injection
- Treatment of Invasive Aspergillosis
- Fungal infections
- Severe fungal infections
- Dandruff
Benefits of Zisavel Injection
Treatment of Invasive Aspergillosis
Invasive Aspergillosis occurs when the infection spreads rapidly from the lungs to the brain, heart, kidneys or skin, in patients with compromised immunity, such as those under cancer therapy, bone marrow transplantation or any other immune related disorder. Zisavel 200 Injection helps treat invasive Aspergillosis and helps you recover faster. Follow your doctor’s instructions carefully while on treatment with Zisavel 200 Injection.
Invasive Aspergillosis occurs when the infection spreads rapidly from the lungs to the brain, heart, kidneys or skin, in patients with compromised immunity, such as those under cancer therapy, bone marrow transplantation or any other immune related disorder. Zisavel 200 Injection helps treat invasive Aspergillosis and helps you recover faster. Follow your doctor’s instructions carefully while on treatment with Zisavel 200 Injection.
Side effects of Zisavel Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zisavel
- Abnormal liver function tests
- Headache
- Decreased potassium level in blood
- Breathlessness
- Nausea
- Vomiting
- Constipation
- Diarrhea
How to use Zisavel Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Zisavel Injection works
Zisavel 200 Injection contains Isavuconazole, an antifungal medicine that blocks the activity of an enzyme that aids in the synthesis of ergosterol, a key component of the fungal cell membrane. As a result, the fungus fails to grow and multiply. This kills the infection causing fungus and clears the infection.
Quick tips
- Zisavel 200 Injection is used for the treatment of certain fungal infections in adults.
- Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
- Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Zisavel 200 Injection.
- Zisavel 200 Injection might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
- Let your doctor know if you are pregnant or breastfeeding.
- Zisavel 200 Injection is used for the treatment of certain fungal infections in adults.
- Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
- Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Zisavel 200 Injection.
- Zisavel 200 Injection might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
- Let your doctor know if you are pregnant or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zisavel 200 Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Zisavel 200 Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Zisavel 200 Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Zisavel 200 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
Zisavel 200 Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver
CAUTION
Zisavel 200 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, clinical monitoring for isavuconazole-related adverse reactions is recommended when treating patients with severe hepatic impairment.
However, clinical monitoring for isavuconazole-related adverse reactions is recommended when treating patients with severe hepatic impairment.

Interaction with drugs
Taking Zisavel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Ranolazine (Oral Route)
Watch out for symptoms of Isavuconazole side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may adjust the dose of Isavuconazole accordingly. Isavuconazole may raise blood levels of Ranolazine.
Severe
Fosphenytoin (Injection Route)
Do not consume Isavuconazole with Fosphenytoin. Fosphenytoin may reduce blood levels of Isavuconazole.
Severe
Nevirapine (Oral Route)
Do not consume Isavuconazole with Nevirapine. Nevirapine may reduce blood levels of Isavuconazole.
Severe
Vinblastine (Injection Route)
Concomitant use is not recommended. Please consult with your doctor. Isavuconazole may raise blood levels of Vinblastine.
Frequently asked questions
Zisavel 200 Injection is a broad spectrum activity antifungal medicine, which is safe and effective to use. It is used to treat invasive aspergillosis and mucormycosis.
Before starting treatment with Zisavel 200 Injection, tell your doctor if you have any other health problems, like heart or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.
Zisavel 200 Injection should be taken by anyone who is allergic to Zisavel 200 Injection, or any of its ingredients. Let your doctor know about any medicines that you may be taking like, ketoconazole, carbamazepine, rifampin, long-acting barbiturates, high-dose ritonavir or any herbal supplements, as their use is contraindicated along with Zisavel 200 Injection. Also, if you have any issues with your heart, discuss with your doctor, as there are certain problems of the heart in which the use of Zisavel 200 Injection is contraindicated. It is advised to avoid starting any new medicines while on treatment with Zisavel 200 Injection to avoid any unwanted sid effects. If you are not sure, please consult your doctor.
No, do not stop taking Zisavel 200 Injection without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
If you forget a dose of Zisavel 200 Injection, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Zisavel 200 Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Fact Box
Chemical Class
Phenylpropanes
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal Ergosterol Synthesis Inhibitor
Related lab tests
References
- Isavuconazonium sulfate [EMC Label]. Sandwich, Kent: Pfizer Limited; 2021. [Accessed 03 Jul. 2021] (online) Available from:
- Isavuconazonium sulfate [Prescription Information]. Northbrook, IL: Astellas Pharma US, Inc.; 2021. [Accessed 03 Jul. 2021] (online) Available from:
- CRESEMBA® (isavuconazonium sulfate). [Accessed 03 Jul. 2021] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: BDR Pharmaceuticals Internationals Pvt
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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