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Zisavel 100mg Tablet 1
Zisavel 100mg Tablet 2

Zisavel 100mg Tablet

Isavuconazole (100mg)
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Zisavel 100mg Tablet is an antifungal medicine. It is used to treat certain types of fungal infections called invasive aspergillosis and invasive mucormycosis in patients 18 years of age and older. It works by stopping the growth of fungi in the body.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 19 Sep 2026 | 01:03 AM (IST)
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Zisavel 100mg Tablet 1
Zisavel 100mg Tablet 2

Product introduction

Zisavel 100mg Tablet can be taken with or without food. Take it exactly as your doctor has advised. Swallow the whole capsule, do not chew, crush, dissolve, or open the capsules. Continue to take the medicine until you finish your complete course, even if symptoms disappear after a few days. Stopping it too early may result in a return of the infection.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, increased liver enzymes, decreased potassium level in blood, constipation, breathlessness, cough, peripheral edema, and back pain. If any of these side effects persist or worsen, consult with your doctor. In rare cases, Zisavel 100mg Tablet may cause serious liver disease. Get medical help right away if you have any symptoms of liver damage, including persistent nausea/vomiting, loss of appetite, stomach/abdominal pain, yellowing eyes/skin, or dark urine.

Before taking the medicine, tell your doctor if you have any known history of allergy to this medicine. Let your doctor also if you have any preexisting medical conditions, especially liver disease and heart problems. This medicine may make you dizzy. Avoid consumption of alcohol while on treatment with this medicine. Additionally, do not drive, use machinery, or do anything that needs alertness until you know how the medicine works. Before taking this medicine, tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause harmful effects to the developing baby.

There is a Patient Support Program / Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Zisavel Tablet

Benefits of Zisavel Tablet

Treatment of Invasive Aspergillosis
Invasive Aspergillosis occurs when the infection spreads rapidly from the lungs to the brain, heart, kidneys or skin, in patients with compromised immunity, such as those under cancer therapy, bone marrow transplantation or any other immune related disorder. Zisavel 100mg Tablet helps treat invasive Aspergillosis and helps you recover faster. Follow your doctor’s instructions carefully while on treatment with Zisavel 100mg Tablet.

Side effects of Zisavel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zisavel
  • Headache
  • Decreased potassium level in blood
  • Breathlessness
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes
  • Abdominal pain

How to use Zisavel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zisavel 100mg Tablet may be taken with or without food.

How Zisavel Tablet works

Zisavel 100mg Tablet contains Isavuconazole, an antifungal medicine that blocks the activity of an enzyme that aids in the synthesis of ergosterol, a key component of the fungal cell membrane. As a result, the fungus fails to grow and multiply. This kills the infection causing fungus and clears the infection.

Quick tips

  • Zisavel 100mg Tablet is used for the treatment of certain fungal infections in adults.
  • Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
  • Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Zisavel 100mg Tablet.
  • Zisavel 100mg Tablet might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
  • Let your doctor know if you are pregnant or breastfeeding.
  • Zisavel 100mg Tablet is used for the treatment of certain fungal infections in adults.
  • Inform your doctor if you have or ever had an abnormal heart rate or rhythm. He/she may ask you to get a test to check your heart (ECG) before starting the treatment.
  • Inform your doctor if you experience serious hypersensitivity and severe skin reactions after taking Zisavel 100mg Tablet.
  • Zisavel 100mg Tablet might interact with certain antibiotics and pain killers. Inform your doctor if you are taking any.
  • Let your doctor know if you are pregnant or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zisavel 100mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zisavel 100mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Zisavel 100mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Zisavel 100mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Zisavel 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Zisavel 100mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
However, clinical monitoring for isavuconazole-related adverse reactions is recommended when treating patients with severe hepatic impairment.

Interaction with drugs

Taking Zisavel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Ranolazine (Oral Route)

Watch out for symptoms of Isavuconazole side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may adjust the dose of Isavuconazole accordingly. Isavuconazole may raise blood levels of Ranolazine.
Severe

Pimozide (Oral Route)

Do not consume Pimozide with Isavuconazole.
Severe

Nevirapine (Oral Route)

Do not consume Isavuconazole with Nevirapine. Nevirapine may reduce blood levels of Isavuconazole.
Severe

Vinblastine (Injection Route)

Concomitant use is not recommended. Please consult with your doctor. Isavuconazole may raise blood levels of Vinblastine.
Severe

Vincristine (Injection Route)

Concomitant use is not recommended. Please consult with your doctor. Isavuconazole may raise blood levels of Vincristine.

Frequently asked questions

Zisavel 100mg Tablet is a broad spectrum activity antifungal medicine, which is safe and effective to use. It is used to treat invasive aspergillosis and mucormycosis.
Before starting treatment with Zisavel 100mg Tablet, tell your doctor if you have any other health problems, like heart or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are planning a baby, if you are pregnant or breastfeeding.
Zisavel 100mg Tablet should be taken by anyone who is allergic to Zisavel 100mg Tablet, or any of its ingredients. Let your doctor know about any medicines that you may be taking like, ketoconazole, carbamazepine, rifampin, long-acting barbiturates, high-dose ritonavir or any herbal supplements, as their use is contraindicated along with Zisavel 100mg Tablet. Also, if you have any issues with your heart, discuss with your doctor, as there are certain problems of the heart in which the use of Zisavel 100mg Tablet is contraindicated. It is advised to avoid starting any new medicines while on treatment with Zisavel 100mg Tablet to avoid any unwanted sid effects. If you are not sure, please consult your doctor.
No, do not stop taking Zisavel 100mg Tablet without consulting your doctor even if you are feeling better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration.
If you forget a dose of Zisavel 100mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Zisavel 100mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Fact Box

Chemical Class

Phenylpropanes

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal Ergosterol Synthesis Inhibitor

Related lab tests

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: BDR Pharmaceuticals Internationals Pvt
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zisavel 100mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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