Zinocarb 50mg Capsule

Procarbazine (50mg)

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Zinocarb 50mg Capsule is used in the treatment of some kinds of cancers. It may be also used to treat other conditions, as determined by the doctor. It is used with other medicines as part of combination chemotherapy to treat cancers such as Hodgkin’s disease (a cancer of the lymph glands).

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Procarbazine (50mg)

Marketer

Miracalus Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Zinocarb 50mg Capsule can be taken with or without food, but better to take it at the same time every day to get the most benefits. Some food or drinks can affect the working of medicine, so better to avoid mature cheeses (including processed cheeses), yeast or meat extracts and some type of beer or alcohol. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Moreover, it can make you infertile, so ask your doctor about safety methods.

Uses of Zinocarb Capsule

Hodgkin’s disease

Benefits of Zinocarb Capsule

Hodgkin’s disease
Hodgkin’s disease is a type of blood cancer that affects the lymphatic system, which helps fight infections. Zinocarb 50mg Capsule is used as part of combination chemotherapy to treat this condition. It works by slowing or stopping the growth of cancer cells, helping control the disease and improving treatment outcomes.

Side effects of Zinocarb Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zinocarb

Nausea
Vomiting
Decreased appetite

How to use Zinocarb Capsule

Take this medicine in the dose and duration as advised by your doctor. Zinocarb 50mg Capsule may be taken with or without food.
Avoid Zinocarb 50mg Capsule with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Zinocarb Capsule works

Procarbazine belongs to a group of medicines called antineoplastic alkylating agents. It works by inhibiting protein, RNA, and DNA synthesis, which helps to stop the growth of cancer cells in the body.

Quick tips

Take it with or without food, but try to have it at the same time every day.
As a precaution, foods high in tyramine (eg. aged cheeses, air-dried meats, soy sauce, tap/draft beers and red wines) should be avoided when taking Zinocarb 50mg Capsule to avoid a serious reaction.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.
Consult with your doctor if you are planning pregnancy as it can affect your fertility.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Zinocarb 50mg Capsule may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

CONSULT YOUR DOCTOR

Zinocarb 50mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Zinocarb 50mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zinocarb 50mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zinocarb 50mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Zinocarb 50mg Capsule is not recommended in patients with severe kidney disease.

Liver

CAUTION

Zinocarb 50mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Zinocarb 50mg Capsule is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Zinocarb with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Amineptine (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Amitriptyline (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Amoxapine (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Immunization with Cholera Vaccine (Inactivated) should be avoided while you’re having Procarbazine treatment and for up to 12 months afterwards. Please consult with your doctor. Procarbazine may reduce efficacy of Cholera Vaccine (Inactivated).

Severe

Clomipramine (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Frequently asked questions

What is Zinocarb 50mg Capsule used for?

Zinocarb 50mg Capsule is a type of chemotherapy medicine used to treat certain cancers, such as Hodgkin’s lymphoma and some brain tumors. It works by slowing or stopping the growth of cancer cells.

How does Zinocarb 50mg Capsule work in cancer treatment?

Zinocarb 50mg Capsule interferes with DNA and protein production in cancer cells, making it harder for them to grow and multiply, which helps control the spread of the disease.

Who should not take Zinocarb 50mg Capsule?

Individuals should not take Zinocarb 50mg Capsule if they are allergic to it, have recently taken monoamine oxidase inhibitors (MAOIs), have severe bone marrow suppression, or have certain serious infections.

Does Zinocarb 50mg Capsule interact with certain foods or drinks?

Yes, Zinocarb 50mg Capsule can interact with foods and drinks high in tyramine, such as aged cheeses, smoked meats, soy products, and some alcoholic beverages. Eating these while you are on Zinocarb 50mg Capsule treatment can cause a sudden rise in blood pressure, which can be dangerous.

Can Zinocarb 50mg Capsule cause allergic reactions?

Although they are rare, allergic reactions to Zinocarb 50mg Capsule include rash, itching, swelling, severe dizziness, or difficulty breathing. If these occur, you should seek medical attention immediately.

Can Zinocarb 50mg Capsule lower immunity?

Yes, Zinocarb 50mg Capsule can reduce the number of white blood cells, making it harder for your body to fight infections. You should avoid close contact with people who are sick, and inform your doctor if you develop fever, chills, or persistent sore throat.

Does Zinocarb 50mg Capsule have any effect on fertility?

Yes, Zinocarb 50mg Capsule can affect fertility in both men and women. In some cases, these effects may be permanent. Patients concerned about fertility should discuss options with their doctor before starting treatment.

What precautions should I follow during Zinocarb 50mg Capsule?

During Zinocarb 50mg Capsule treatment, you should avoid live vaccines, limit exposure to people with contagious illnesses, follow dietary restrictions, and report any unusual bleeding, bruising, or signs of infection to your doctor immediately.

Fact Box

Chemical Class

Benzamide derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1154-55.
Procarbazine. Chippenham, Wiltshire: Alliance Pharmaceuticals; 2006 [revised 24 Nov. 2014. [Accessed 23 Jan. 2019] (online) Avaialble from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Miracalus Pharma Pvt Ltd
Address: 213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.

Vendor Details

Country of origin: India

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Why we need a prescription?

Zinocarb 50mg Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Zinocarb Capsule

Benefits of Zinocarb Capsule

Side effects of Zinocarb Capsule

How to use Zinocarb Capsule

How Zinocarb Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Amineptine (Oral Route)

Amitriptyline (Oral Route)

Amoxapine (Oral Route)

Cholera Vaccine (Inactivated) (Oral Route)

Clomipramine (Oral Route)

Frequently asked questions

What is Zinocarb 50mg Capsule used for?

How does Zinocarb 50mg Capsule work in cancer treatment?

Who should not take Zinocarb 50mg Capsule?

Does Zinocarb 50mg Capsule interact with certain foods or drinks?

Can Zinocarb 50mg Capsule cause allergic reactions?

Can Zinocarb 50mg Capsule lower immunity?

Does Zinocarb 50mg Capsule have any effect on fertility?

What precautions should I follow during Zinocarb 50mg Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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