Zinocarb 50mg Capsule is used in the treatment of some kinds of cancers. It may be also used to treat other conditions, as determined by the doctor. It is used with other medicines as part of combination chemotherapy to treat cancers such as Hodgkin’s disease (a cancer of the lymph glands).

Zinocarb 50mg Capsule can be taken with or without food, but better to take it at the same time every day to get the most benefits. Some food or drinks can affect the working of medicine, so better to avoid mature cheeses (including processed cheeses), yeast or meat extracts and some type of beer or alcohol. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood cells along with the heart, liver, and kidney.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Moreover, it can make you infertile, so ask your doctor about safety methods.

Uses of Zinocarb Capsule

Hodgkin’s disease

Benefits of Zinocarb Capsule

In Hodgkin’s disease

Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Zinocarb 50mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.

Side effects of Zinocarb Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zinocarb

Nausea
Vomiting
Decreased appetite

How to use Zinocarb Capsule

Take this medicine in the dose and duration as advised by your doctor. Zinocarb 50mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Avoid Zinocarb 50mg Capsule with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Zinocarb Capsule works

Procarbazine belongs to a group of medicines called antineoplastic alkylating agents. It works by inhibiting protein, RNA, and DNA synthesis, which helps to stop the growth of cancer cells in the body.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Zinocarb 50mg Capsule may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Zinocarb 50mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Zinocarb 50mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zinocarb 50mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Zinocarb 50mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zinocarb 50mg Capsule may be needed. Please consult your doctor.
Use of Zinocarb 50mg Capsule is not recommended in patients with severe kidney disease.

Liver

CAUTION

Zinocarb 50mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Zinocarb 50mg Capsule may be needed. Please consult your doctor.
Use of Zinocarb 50mg Capsule is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Zinocarb 50mg Capsule

₹33.9/Capsule

Hodpro 50mg Capsule

Neon Laboratories Ltd

₹41.3/capsule

22% costlier

Quick tips

Take it with or without food, but try to have it at the same time every day.
As a precaution, foods high in tyramine (eg. aged cheeses, air-dried meats, soy sauce, tap/draft beers and red wines) should be avoided when taking Zinocarb 50mg Capsule to avoid a serious reaction.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.
Consult with your doctor if you are planning pregnancy as it can affect your fertility.

Fact Box

Chemical Class

Alkylating agents, methylhydrazine derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Patient concerns

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1154-55.
Procarbazine. Chippenham, Wiltshire: Alliance Pharmaceuticals; 2006 [revised 24 Nov. 2014. [Accessed 23 Jan. 2019] (online) Avaialble from:
Drugs.com. Procarbazine Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Marketer details

Name: Miracalus Pharma Pvt Ltd

Address: 213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.