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Zilance 40 Tablet is a medicine used to treat high blood pressure and heart failure. Lowering blood pressure helps to prevent future heart attacks and strokes. This medicine is also effective in preserving kidney function in patients with diabetes.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)
₹82.6 MRP ₹89.628% off 
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General Information

The content is shown in English
Zilance 40 Tablet image
Zilance 40 Tablet image
Zilance 40 Tablet image
Zilance 40 Tablet image
Zilance 40 Tablet image
Zilance 40 Tablet image
Zilance 40 Tablet image

Product introduction

Zilance 40 Tablet can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use.


Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet, as advised by your doctor. This medicine is tolerated well by most patients and has few side effects. Dizziness, particularly after the first dose, is known to occur in some people. This may be associated with headache. Let your doctor know if these side effects bother you or do not go away. No weight gain has been seen with the regular use of this medicine.


Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.

Uses of Zilance Tablet

Benefits of Zilance Tablet

Hypertension (high blood pressure)
Hypertension is a condition where the force of blood against the artery walls remains too high for a long time, putting extra strain on the heart and blood vessels. Zilance 40 Tablet helps lower blood pressure by relaxing blood vessels, making it easier for the heart to pump. This reduces the risk of heart attacks, strokes, and kidney damage when taken regularly.
Heart Failure
Heart failure happens when the heart cannot pump enough blood to meet the body's needs, causing fatigue, shortness of breath, and fluid buildup. Zilance 40 Tablet eases the heart’s workload by reducing blood pressure and improving blood flow, which helps relieve symptoms and slow down disease progression.
Prevention of heart attack and stroke
Zilance 40 Tablet helps keep the blood pressure under control and helps improve blood flow. This helps lower the risk of serious cardiovascular events like heart attacks and strokes, especially in individuals with existing risk factors. It supports overall heart and vascular health when used consistently as prescribed.

Side effects of Zilance Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zilance
  • Dizziness
  • Muscle damage
  • Diarrhea

How to use Zilance Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zilance 40 Tablet may be taken with or without food.

How Zilance Tablet works

Zilance 40 Tablet is an angiotensin receptor blocker (ARB). It relaxes the blood vessels by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently.

Quick tips

  • Take it at the same time every day to help you remember to take it.
  • It can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
  • Your doctor may get regular tests done to monitor the level of urea, creatinine, and potassium in your blood.
  • Avoid taking anti-inflammatory medicines such as ibuprofen along with this medicine without consulting your doctor.
  • Do not take Zilance 40 Tablet if you are pregnant or breastfeeding.
  • Do not stop taking it suddenly without talking to your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zilance 40 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zilance 40 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Zilance 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CAUTION
Zilance 40 Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Zilance 40 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Zilance 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zilance with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Amiloride (Oral Route)

Do not consume Azilsartan medoxomil with Amiloride if you have kidney disorders. If concurrent use is essential, your doctor may monitor your potassium levels closely. and adjust the dose of Amiloride as per the observations.
Severe

Co-trimoxazole (Oral Route)

Do not consume Azilsartan medoxomil with Co-trimoxazole. If concurrent use is essential, please consult your doctor. They may monitor your potassium levels closely.
Severe

Eplerenone (Oral Route)

If concurrent use is essential, watch out for symptoms such as muscle weakness, fatigue, cramps, nausea, vomiting, tingling, numbness or irregular heartbeat and consult your doctor if you experience them. They may also monitor your potassium levels closely.
Severe

Spironolactone (Oral Route)

If concurrent use is essential, watch out for symptoms such as dizziness, fatigue, confusion, weight loss, tingling in hands and feet, nausea, diarrhea, loss of appetite, difficulty concentrating, or taste changes, and consult your doctor if you experience them. They may adjust the doses as per the observations.
Severe

Triamterene (Oral Route)

Do not consume Azilsartan medoxomil with Triamterene if you have kidney disorders. If concurrent use is essential, your doctor may monitor your potassium levels closely. and adjust the dose of Triamterene as per the observations.

Frequently asked questions

Both Zilance 40 Tablet and telmisartan are blood pressure-lowering medicines. Zilance 40 Tablet is a relatively new medicine. It has been found to be as effective as telmisartan in lowering blood pressure. It can be safely used in patients as it has fewer side effects.
You should take Zilance 40 Tablet exactly as directed by your doctor. It is for oral use and is usually taken once a day. You should take it with plenty of water, with or without food. It is recommended that you take this medicine at the same time every day.
No, do not stop taking Zilance 40 Tablet without speaking to your doctor, even if you are feeling well or your blood pressure is controlled. Stopping it suddenly may increase your blood pressure which may increase your risk of stroke.
Zilance 40 Tablet may take about 2 weeks to show a visible reduction in blood pressure. Full benefits of Zilance 40 Tablet may take a little longer, about 4 weeks.
Taking more than the recommended dose of Zilance 40 Tablet may decrease your blood pressure due to which you may feel dizzy or may even faint. Consult your doctor immediately or seek emergency medical aid in a nearby hospital.
Zilance 40 Tablet belongs to a class of medicines called angiotensin II receptor antagonists (AIIRAs). Angiotensin II is a substance which occurs naturally in the body. It tightens the blood vessels, which in turn increases the blood pressure. Zilance 40 Tablet blocks this effect so that the blood vessels relax, which helps lower your blood pressure.
It is important for you to know that this medicine can cause harm or death to your unborn baby. Therefore, if you are planning a pregnancy or have become pregnant, consult your doctor right away. Your doctor may switch you to a different medicine to treat your high blood pressure.
You should not take Zilance 40 Tablet if you are allergic to it or if you are pregnant. Avoid its use if you have diabetes or impaired kidney function and are being treated with a blood pressure-lowering medicine containing aliskiren.

Fact Box

Chemical Class

Biphenyl derivative

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Angiotensin Receptor Blockers (ARBs)

Related lab tests

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User feedback

Once A Day
77%
Twice A Day
22%
Alternate Day
1%
Hypertension (high blood pressure)
100%
Average
53%
Excellent
27%
Poor
20%
No Side Effect
100%
With food
67%
Empty stomach
33%
Average
56%
Expensive
22%
Not Expensive
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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