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Spironolactone

INFORMATION

Uses

Spironolactone is used in the treatment of increased blood pressure , heart failure, cirrhosis and low potassium.

How it works

Spironolactone lowers blood pressure and swelling by increasing the amount of urine, which removes extra water and certain electrolytes from the body. Spironolactone does this without loss of potassium from the body.

Common side effects

Abdominal pain, Abnormal vaginal bleeding, Bloody diarrhea, Breast tenderness, Breast enlargement, Dizziness, Drowsiness, Dry mouth, Fatigue, Headache, Hoarseness of voice, Increased hair growth, Impotence, Restlessness, Unsteadiness, Bloating, Vomiting, Absence of menstrual periods, Irregular menstrual cycle, Excessive thirst

AVAILABLE MEDICINE

Expert advice

The medicine  can make you feel dizzy or sleepy. Avoid driving or operating machinery until you know how the medicine affects you.
Do not use supplements or salt substitutes that are high in potasium. Consult your doctor if you develop any muscle weakness, skin changes, red or black tarry stool. Avoid taking alcohol with this medication as it may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position.
Do not start or continue spironolactone and consult your doctor:
  • If you have kidney disease, Addison’s disease (an adrenal gland disorder), liver disease, heart disease.
  • If you have high levels of potassium in your blood (hyperkalemia).
  • if you are also taking eplerenone or other potassium sparing diuretics.
  • If you have an electrolyte imbalance (such as low levels of magnesium in your blood).
  • if you take an NSAID (nonsteroidal anti-inflammatory drug), cholestyramine, heparin, lithium, heart or blood pressure medication, potassium supplements, steroid medicine, or another diuretic.

Frequently asked questions

Spironolactone

Q.Is spironolactone an ACE inhibitor/thiazide diuretic/corticosteroid/steroid/ beta blocker?
No, spironolactone belongs to a class of medications called aldosterone receptor antagonists

Q.Is spironolactone safe?
Spironolactone is safe, if used at prescribed doses for the prescribed duration as advised by your doctor

Q.Is spironolactone over the counter drug?
No, it is available as prescription drug

Q.Is spironolactone used for weight control, birth control, for acne, loss of hair?
No, spironolactone is used in the treatment of failure of heart, resulting in fluid build-up in lungs or other body tissue (congestive cardiac failure), chronic liver disease (hepatic cirrhosis) with accumulation of fluid in peritoneum liver (ascites and edema), malignant ascites, nephrotic syndrome, diagnosis and treatment of primary aldosteronism

Q.What is spironolactone/Dytor plus/Aldactone?
Spironolactone/Dytor plus/Aldactone belongs to a class of medications called aldosterone receptor antagonists

Q.Can spironolactone/Dytor plus/Aldactone cause cancer, hair loss, depression, insomnia, lower blood pressure, constipation, increase estrogen, weight loss?
Spironolactone/Dytor plus/Aldactone can causes hair loss, increase estrogen constipation. Always consult your doctor about possible side effects

Q.Can i take spironolactone/Aldactone with ibuprofen/vitamins/ antibiotics/ phentermine/ metformin amoxicillin/ Adderall(amphetamine and dextroamphitamine/ Accutane (isotretinoin)/ Benadryl (diphenhydramine)/ Tylenol (acetaminophen)/ Lasix (furosemide)?
Indometacin may increase the diuretic effect of spironolactone. Patients should follow doctors advice regarding its use

Q.Does spironolactone affect birth control?
No, Always consult your doctor about possible effects.


Content on this page was last updated on 24 November, 2016, by Dr. Varun Gupta (MD Pharmacology)