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    Information about Spironolactone

    Spironolactone uses

    Spironolactone is used in the treatment of Hypertension (high blood pressure) and Edema. It treats oedema (fluid overload) associated with heart, liver, kidney or lung disease.

    How spironolactone works

    Spironolactone is a potassium-sparing diuretic. It lowers blood pressure and swelling by removing the extra water and electrolytes from the body without loss of potassium.

    Common side effects of spironolactone

    Nausea, Vomiting, Leg cramps, Dizziness, Drowsiness, Confusion, Breast enlargement in male, Increased creatinine level in blood
    Content Details
    Written By
    Dr. Anuj Saini
    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    18 Feb 2020 | 05:21 PM (IST)
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    Available Medicine for Spironolactone

    • ₹25 to ₹772
      Aimil Pharmaceuticals India Ltd
      56 variant(s)
    • ₹31 to ₹175
      RPG Life Sciences Ltd
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    • ₹25 to ₹49
      Sun Pharmaceutical Industries Ltd
      2 variant(s)
    • ₹19 to ₹39
      Psychocare Health Pvt Ltd
      2 variant(s)

    Expert advice for Spironolactone

    • It can make you feel dizzy for the first few days. Do not drive or do anything requiring concentration until you know how Spironolactone affects you.
    • It may increase the level of potassium in your blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
    • Spironolactone may cause breast pain/swelling, irregular periods (women), or trouble with sexual performance.
    • Your doctor will regularly check your kidney function and the amount of potassium in your blood while you are on this medicine.
    • Notify your doctor if you experience dizziness, diarrhea, vomiting, fast or irregular heartbeat, swelling in feet, or difficulty breathing.
    • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

    Frequently asked questions for Spironolactone


    Q. What is spironolactone?

    Spironolactone is a diuretic and belongs to the class of potassium-sparing diuretics (water tablets), which help lose excess fluid from your body. They may be used for congestive heart failure, nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (oedema) and swelling of the abdomen (ascites). This medicine may also be used in a cancerous disease with swelling of the abdomen (malignant ascites) and diagnosis and treatment of primary aldosteronism (a condition where excess hormone is produced).

    Q. Can spironolactone cause constipation?

    Spironolactone has not been reported to cause constipation. Talk to your doctor if you have constipation while taking spironolactone as it could be due to some other underlying condition.

    Q. Can I use spironolactone for weight control?

    No, Spironolactone should not be used for weight control. It does not cause weight loss. Please consult a doctor who will let you know the best therapy for weight control.

    Q. Can I take spironolactone with birth control?

    Spironolactone can be taken with birth control pills (oral contraceptives) as no drug-drug interactions or side effects have been reported when used together. However, interactions can occur. Therefore, talk to your doctor before taking spironolactone with any birth control pills (oral contraceptives).

    Q. Is spironolactone a blood pressure medication?

    Spironolactone is not indicated for the treatment of high blood pressure. However, it is a diuretic, which helps you lose excess fluid from your body and can lower your blood pressure, especially if you are also taking other drugs to lower your blood pressure. Talk to your doctor before taking spironolactone if you have high blood pressure and taking blood pressure and taking medicines to lower it.

    Q. Is spironolactone harmful to kidneys?

    Spironolactone can lead to acute kidney failure particularly in those who already have impaired kidney function. Please tell your doctor if you have kidney problems as you may need a different dose and may also require close monitoring of your kidney function test.

    Content on this page was last updated on 18 February, 2020, by Dr. Varun Gupta (MD Pharmacology)