Zerolef 10mg Tablet
Prescription Required
View available alternative with same salt composition
Product introduction
Zerolef 10mg Tablet is used in the treatment of rheumatoid arthritis. It helps in slowing down the progression of the disease and provides relief from pain, swelling, and redness associated with the condition.
Zerolef 10mg Tablet can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
Using this medicine may cause some common side effects such as nausea, headache, dyspepsia, rash, diarrhea, and increased liver enzymes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check and make sure the medicine is not harming your liver or affecting your blood counts. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Uses of Zerolef Tablet
Benefits of Zerolef Tablet
In Treatment of Rheumatoid arthritis
Zerolef 10mg Tablet reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.
Side effects of Zerolef Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zerolef
- Headache
- Weight loss
- High blood pressure
- Skin disorder
- Musculoskeletal (bone, muscle or joint) pain
- Paresthesia (tingling or pricking sensation)
- Dizziness
How to use Zerolef Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zerolef 10mg Tablet may be taken with or without food.
How Zerolef Tablet works
Zerolef 10mg Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain autoimmune diseases such as rheumatoid arthritis. It suppresses the underlying disease process, rather than simply treating the disease.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Zerolef 10mg Tablet
Pregnancy
UNSAFE
Zerolef 10mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
UNSAFE
Zerolef 10mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Zerolef 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
UNSAFE
Zerolef 10mg Tablet is unsafe to use in patients with kidney disease and should be avoided.
Liver
UNSAFE
Zerolef 10mg Tablet is unsafe to use in patients with liver disease and should be avoided.
What if you forget to take Zerolef Tablet?
If you miss a dose of Zerolef 10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Zerolef 10mg Tablet
₹9.18/Tablet
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Quick tips
- You have been prescribed Zerolef 10mg Tablet to control the symptoms and slow down the progression of rheumatoid arthritis.
- It will take 6-8 weeks for Zerolef 10mg Tablet to work. Hence, keep taking the medicine.
- Get blood tests done every 4 weeks. This is to make sure that Zerolef 10mg Tablet is not harming your liver or blood counts.
- Avoid alcohol when taking Zerolef 10mg Tablet as it could harm your liver.
- Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Zerolef 10mg Tablet.
- Zerolef 10mg Tablet may increase the risk of infection. Avoid being close to people with colds, flu, or other contagious illnesses.
Fact Box
Chemical Class
Aromatic anilides
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
Interaction with drugs
Taking Zerolef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Natalizumab with Leflunomide.
Long-term concurrent use may increase the risk of certain brain infections.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Leflunomide or for up to 6 months after stopping Leflunomide.
Concomi
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of damage to the liver an
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of damage to the liver an
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of damage to the liver an
Patient concerns
FAQs
Can Zerolef 10mg Tablet cause weight loss?
Yes, Zerolef 10mg Tablet may cause weight loss as a common side effect. However, weight loss due to this medicine is usually insignificant. The reason for this weight reduction could be due to the accompanying loss of appetite. Consult your doctor if your weight loss is significant.
When should patients notify their doctor?
The doctor should be informed if one has lung problems like cough, shortness of breath, or if one observes symptoms of infection like fever, weakness, and flu-like symptoms. Along with that, if a person experiences allergic reactions like hives, rashes, and liver problems like yellowing of skin, loss of appetite, then they should be consulted with the doctor. One should also inform the doctor if there is a decrease in blood cell count, causing easy bruising and recurrent infections. In addition to that, the doctor should be informed if one becomes pregnant during the course of treatment.
Can I plan a pregnancy after stopping Zerolef 10mg Tablet?
Zerolef 10mg Tablet takes a fairly long time to get flushed out of your system. Hence, you should not plan pregnancy for at least 2 years after stopping Zerolef 10mg Tablet. This extensive time duration may be reduced to a few weeks by taking certain medicines, which can help speed up the removal of Zerolef 10mg Tablet from your body.
How long does it take to see improvement after starting Zerolef 10mg Tablet?
Zerolef 10mg Tablet may take about 4 weeks or longer to show improvement in the condition. It may even take 4-6 months to show full benefits. Hence, the medicine should not be stopped if there is no significant improvement. For any further query consult your doctor, who will analyze the condition.
Can Zerolef 10mg Tablet cause cancer?
Zerolef 10mg Tablet may increase your chances of cancer, especially of the lymph system, but this is very rare. The reason could be decreased strength of the immune system caused by Zerolef 10mg Tablet. Discuss with your doctor if you have concerns regarding it.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 631.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 781-84.
- Leflunomide [Prescribing Information]. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC; 1998 [Aug. 2015]. [Accessed 24 Jan. 2019] (online) Available from:
- Leflunomide [Prescribing Information]. Bridgewater, New Jersey: Sanofi-Aventis U.S; 2010. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Leflunomide. [Accessed 08 Jul. 2023]. (online) Available from:
- CiplaMed. Leflunomide [Prescribing Information]. [Last Revised: 13 May 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
- Memorial Sloan Kettering Cancer Center. Leflunomide. [Last Updated: 12 Dec. 2022]. [Accessed 08 Jul. 2023]. (online) Available from:
- Leflunomide [Product Monograph]. Toronto, Ontario: Apotex Inc.; 2023. [Accessed 17 Jan. 2026]. (online) Available from:
Marketer details
Name: Actus Health Care
Address: 4507, TNHB Colony, Villapuram, Madurai, Tamil Nadu, 625012, India
Country of origin: India
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₹91.8
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MRP₹103.13 11% OFF
10.0 tablets in 1 strip
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Leflunomide (10mg)
