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Zep 200mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 13 Apr 2026 | 07:29 PM (IST)
Zep 200mg Tablet is an anti-epileptic medicine used to treat epilepsy. It helps prevent certain types of seizures (fits). It is also prescribed for a painful condition of the face, head, and neck known as trigeminal neuralgia and diabetes-related nerve pain (diabetic neuropathy).
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General Information

The content is shown in English
Zep 200mg Tablet image
Zep 200mg Tablet image

Product introduction

Zep 200mg Tablet must be taken with or without food, but take it at the same time every day. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. It may be increased gradually. Many other medicines can interfere with this medicine so tell your doctor about all the medicines you are taking to make sure it is safe.

You can take this medicine with or without food but take it regularly at the same time each day to get the maximum benefit. It is important to take this medicine for as long as you are advised, even if you feel well. Missing even a single dose may trigger a seizure and, if you stop taking it abruptly, your condition may get worse.

The most common side effects of this medicine include nausea, vomiting, feeling dizzy, tired or drowsy, unsteadiness (balance disorder), constipation, dry mouth, and itching. Some people may develop blurring of vision and slurred speech. Most of the side effects are not serious. However, let your doctor know straight away if you notice a skin rash or if your mood becomes depressed or if you develop any thoughts about harming yourself.

Before taking Zep 200mg Tablet, tell your doctor if you have any heart problems, kidney or liver disease, difficulty in urinating, or any mental illness like depression. These conditions may affect your treatment. You may be advised some blood tests (eg. CBC) before starting treatment and then periodically thereafter, to monitor your progress.

Benefits of Zep Tablet

Trigeminal neuralgia
Trigeminal neuralgia is a condition that causes sudden, severe facial pain due to irritation of the trigeminal nerve. Zep 200mg Tablet helps reduce the frequency and intensity of pain episodes, making everyday activities like speaking, chewing, and brushing teeth more manageable. With regular use, it can provide sustained pain relief and improve comfort and quality of life.
Epilepsy/Seizures
Zep 200mg Tablet works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.

This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Zep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zep
  • Nausea
  • Dizziness
  • Vomiting
  • Constipation
  • Sleepiness
  • Abnormality of voluntary movements

How to use Zep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zep 200mg Tablet may be taken with or without food.

How Zep Tablet works

Zep 200mg Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Your doctor may get regular tests done to monitor the level of blood cells in your blood while taking this medication. 
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Inform your doctor if you notice a rash or other skin changes such as reddish spot or circular patches while taking this medicine.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zep 200mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Zep 200mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Zep 200mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Zep 200mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Zep 200mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Zep 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Zep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Ticagrelor (Oral Route)

Do not consume Ticagrelor with Carbamazepine. Carbamazepine may reduce blood levels of Ticagrelor.
Severe

Ranolazine (Oral Route)

Do not consume Ranolazine with Carbamazepine. Carbamazepine may reduce blood levels and efficacy of Ranolazine.
Severe

Clarithromycin (Oral Route)

If concurrent use is essential, watch out for symptoms such as impaired coordination, double vision, dizziness or confusion and consult your doctor if you experience them. Your doctor may monitor and adjust the dose of Carbamazepine accordingly. Clarithromycin may raise blood levels of Carbamazepine.
Severe

Clarithromycin (Injection Route)

If concurrent use is essential, watch out for symptoms such as impaired coordination, double vision, dizziness or confusion and consult your doctor if you experience them. Your doctor may monitor and adjust the dose of Carbamazepine accordingly. Clarithromycin may raise blood levels of Carbamazepine.
Severe

Clarithromycin (Oral Route)

If concurrent use is essential, watch out for symptoms such as impaired coordination, double vision, dizziness or confusion and consult your doctor if you experience them. Your doctor may monitor and adjust the dose of Carbamazepine accordingly. Clarithromycin may raise blood levels of Carbamazepine.

Frequently asked questions

Your symptoms may take 1-2 weeks to improve. However, in some cases, it may take even longer. Consult your doctor if your condition doesn't improve or if you have any doubts regarding your condition.
No, Zep 200mg Tablet is not an analgesic and should not be used for regular aches or pains. It is an anti-epileptic medicine which is used to treat fits (seizures). It is also used in the treatment of trigeminal neuralgia (intense facial nerve pain). In addition to that, Zep 200mg Tablet is used to control mood disorders when other medicines fail to work.
Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), medicines to control bacterial infection (e.g., chloramphenicol, metronidazole and doxycycline) and medicines to control viral infection (e.g., nelfinavir). Also, let your doctor know if you take asthma medicines (e.g., theophylline and montelukast), birth control pills, etc. It is important to tell your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems or porphyria (a rare blood pigment disorder).
The long-term side effects of Zep 200mg Tablet vary from person to person. While some people can take Zep 200mg Tablet safely for several years, some may develop side effects on using it for long term. These side effects include osteoporosis and osteopenia in which the bones become weak and can get easily fractured. Therefore, if you have been prescribed Zep 200mg Tablet for a long term, get your bone density checked at regular intervals, maintain a healthy diet and exercise daily.
Zep 200mg Tablet may make you sleepy or you may feel dizzy. Therefore, avoid driving or operating heavy machinery. Alcohol consumption should be avoided since taking both together may cause excessive sleepiness.
You should stop Zep 200mg Tablet only after consulting your doctor. It is advised to gradually decrease the dose of Zep 200mg Tablet so that the condition for which you are taking it does not recur.
Pay attention to any changes, especially sudden changes in mood, behavior, thoughts or feelings. Keep all follow-up visits with your doctor as scheduled. Call your doctor as needed, especially if you are worried about any symptoms.
Yes, Zep 200mg Tablet causes weight gain as a common side effect. This could be due to an increase in appetite. You can manage your weight by eating a healthy diet, consuming low calorie food and including more vegetables and fruits in your diet. Also, regular physical exercise will be very helpful.
Though rare but Zep 200mg Tablet may cause decreased sexual desire. It may also impair male fertility as it may reduce sperm count and/or motility. Consult your doctor if you develop these symptoms.
Once the medicine relieves your pain, talk to your doctor who will gradually reduce your dose. Zep 200mg Tablet can be possibly stopped if there is no recurrence of pain after taking the reduced dose for several weeks.
Side effects of Zep 200mg Tablet can be reduced by starting it at a low dose. The doctor may gradually increase the dose, until an effective dose is reached.
Before starting treatment with Zep 200mg Tablet, your doctor may ask you to get regular blood tests, liver function test, and in some cases, even a urine test. You may need to take these tests from time to time during your treatment. This is quite usual and nothing to worry about.
No, Zep 200mg Tablet is not an analgesic and should not be used for regular aches or pains. It is an anti-epileptic medicine which is used to treat fits (seizures). It is also used in the treatment of trigeminal neuralgia (intense facial nerve pain). In addition to that, Zep 200mg Tablet is used to control mood disorders when other medicines fail to work.
The long-term side effects of Zep 200mg Tablet vary from person to person. While some people can take Zep 200mg Tablet safely for several years, some may develop side effects on using it for long term. These side effects include osteoporosis and osteopenia in which the bones become weak and can get easily fractured. Therefore, if you have been prescribed Zep 200mg Tablet for a long term, get your bone density checked at regular intervals, maintain a healthy diet and exercise daily.
You should stop Zep 200mg Tablet only after consulting your doctor. It is advised to gradually decrease the dose of Zep 200mg Tablet so that the condition for which you are taking it does not recur.
Your symptoms may take 1-2 weeks to improve. However, in some cases, it may take even longer. Consult your doctor if your condition doesn't improve or if you have any doubts regarding your condition.
Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), medicines to control bacterial infection (e.g., chloramphenicol, metronidazole and doxycycline) and medicines to control viral infection (e.g., nelfinavir). Also, let your doctor know if you take asthma medicines (e.g., theophylline and montelukast), birth control pills, etc. It is important to tell your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems or porphyria (a rare blood pigment disorder).
Zep 200mg Tablet may make you sleepy or you may feel dizzy. Therefore, avoid driving or operating heavy machinery. Alcohol consumption should be avoided since taking both together may cause excessive sleepiness.
Pay attention to any changes, especially sudden changes in mood, behavior, thoughts or feelings. Keep all follow-up visits with your doctor as scheduled. Call your doctor as needed, especially if you are worried about any symptoms.
Yes, Zep 200mg Tablet causes weight gain as a common side effect. This could be due to an increase in appetite. You can manage your weight by eating a healthy diet, consuming low calorie food and including more vegetables and fruits in your diet. Also, regular physical exercise will be very helpful.
Though rare but Zep 200mg Tablet may cause decreased sexual desire. It may also impair male fertility as it may reduce sperm count and/or motility. Consult your doctor if you develop these symptoms.
Once the medicine relieves your pain, talk to your doctor who will gradually reduce your dose. Zep 200mg Tablet can be possibly stopped if there is no recurrence of pain after taking the reduced dose for several weeks.
Side effects of Zep 200mg Tablet can be reduced by starting it at a low dose. The doctor may gradually increase the dose, until an effective dose is reached.
Before starting treatment with Zep 200mg Tablet, your doctor may ask you to get regular blood tests, liver function test, and in some cases, even a urine test. You may need to take these tests from time to time during your treatment. This is quite usual and nothing to worry about.

Fact Box

Chemical Class

Dibenzazepines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

References

  1. Stahl SM, editor. Carbamazepine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 105-110.
  2. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 594-95.
  3. Porters RJ, Meldrum BS. Antiseizure Drugs. Sedative-Hypnotic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 405-406.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 197-201.
  5. Carbamazepine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2018. [Accessed 19 Jun. 2019] (online) Available from:
  6. Carbamazepine. Hoofddorp, The Netherlands: Sun Pharmaceutical Industries Europe B.V.; 2019. [Accessed 06 Feb. 2019] (online) Available from:
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:
  9. Carbamazepine [Drug Label]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2009. [Accessed 25 Jul. 2024] (online) Available from:
  10. Carbamazepine [Drug Label]. Vapi, Gujarat: Nivagen Pharmaceuticals Inc.; 2024. [Accessed 25 Jan. 2026] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Zep 200mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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