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Xipra Sublingual tablet
Prescription Required
Product introduction
Xipra Sublingual tablet is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles. It may also be used after a dental surgery.
Xipra Sublingual tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. Take it exactly as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, indigestion, and diarrhea. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Xipra Sublingual tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. Take it exactly as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous.
The most common side effects of this medicine include mild vomiting, stomach pain, nausea, indigestion, and diarrhea. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.
Uses of Xipra Sublingual tablet
Benefits of Xipra Sublingual tablet
In Pain relief
Xipra Sublingual tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Xipra Sublingual tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xipra
- Vomiting
- Stomach pain
- Nausea
- Headache
- Dizziness
How to use Xipra Sublingual tablet
Place the tablet under the tongue or between the cheek and gum, and let it dissolve. Do not chew, crush, or swallow the tablet. Xipra Sublingual tablet is to be taken with food.
How Xipra Sublingual tablet works
Xipra Sublingual tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Xipra Sublingual tablet.
Pregnancy
CONSULT YOUR DOCTOR
Xipra Sublingual tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Xipra Sublingual tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Xipra Sublingual tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Xipra Sublingual tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Xipra Sublingual tablet may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Xipra Sublingual tablet should be used with caution in patients with liver disease. Dose adjustment of Xipra Sublingual tablet may be needed. Please consult your doctor.
What if you forget to take Xipra Sublingual tablet?
If you miss a dose of Xipra Sublingual tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Xipra Sublingual tablet helps relieve pain and swelling of various joints and muscles.
- Take it with food to avoid stomach upset.
- Your doctor will prescribe you the lowest effective dose of this medicine for the shortest possible time necessary to relieve your symptoms.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Fact Box
Chemical Class
Enolic acid Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)
Interaction with drugs
Taking Xipra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Neil, Esulide
Life-threatening
Brand(s): Oxy Triactin, Sioril
Life-threatening
Brand(s): Pyregin, Alpagin, Bral
Life-threatening
Patient concerns
FAQs
Q. What is the difference between Xipra Sublingual tablet and diclofenac?
Both Xipra Sublingual tablet and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Xipra Sublingual tablet.
Q. What is the difference between Xipra Sublingual tablet and naproxen?
Both Xipra Sublingual tablet and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Xipra Sublingual tablet.
Q. What is the difference between Xipra Sublingual tablet and meloxicam?
Both Xipra Sublingual tablet and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Xipra Sublingual tablet.
Q. What is the difference between Xipra Sublingual tablet and ketoprofen?
Both Xipra Sublingual tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Xipra Sublingual tablet. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Xipra Sublingual tablet and tramadol?
Xipra Sublingual tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Xipra Sublingual tablet and nimesulide?
Both Xipra Sublingual tablet and nimesulide are pain killers. However, Xipra Sublingual tablet is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Xipra Sublingual tablet be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Xipra Sublingual tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Xipra Sublingual tablet.
Q. Are Xipra Sublingual tablet and aspirin same?
No. Xipra Sublingual tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Xipra Sublingual tablet be used along with dexamethasone?
No. Xipra Sublingual tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Xipra Sublingual tablet be used with methocarbamol?
Yes. Methocarbamol can be used with Xipra Sublingual tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Xipra Sublingual tablet be used along with paracetamol?
Yes. Paracetamol can be used with Xipra Sublingual tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Xipra Sublingual tablet a NSAID?
Yes. Xipra Sublingual tablet is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Xipra Sublingual tablet a sulfa drug?
Xipra Sublingual tablet is a sulphur containing compound. Xipra Sublingual tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Xipra Sublingual tablet a blood thinner?
No. Xipra Sublingual tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Xipra Sublingual tablet a muscle relaxant?
No. Xipra Sublingual tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Xipra Sublingual tablet a narcotic?
No. Xipra Sublingual tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Xipra Sublingual tablet be used in hypertension?
No. Xipra Sublingual tablet is not a medication to control hypertension. It is important to note that Xipra Sublingual tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Xipra Sublingual tablet.
Q. Can Xipra Sublingual tablet be used along with Losartan?
No. Xipra Sublingual tablet should not be combined with Losartan. It is important to note that Xipra Sublingual tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Xipra Sublingual tablet.
Q. Can Xipra Sublingual tablet be used with Lisinopril?
No. Xipra Sublingual tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Xipra Sublingual tablet.
Q. Can Xipra Sublingual tablet be used with calcium channel blocker?
Yes. Xipra Sublingual tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Xipra Sublingual tablet be used with Tizanidine?
Yes, Xipra Sublingual tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Xipra Sublingual tablet?
Yes. Xipra Sublingual tablet can be combined with beta-cyclodextrin. Research has shown that combining Xipra Sublingual tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Xipra Sublingual tablet?
Yes. There are alternatives to Xipra Sublingual tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Xipra Sublingual tablet?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Xipra Sublingual tablet be used in the treatment of allergy?
No. Xipra Sublingual tablet is not a drug to treat allergy. It is a pain killer.
Q. How long does Xipra Sublingual tablet work?
Xipra Sublingual tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Xipra Sublingual tablet?
No. Xipra Sublingual tablet is not known to cause high. It is a non-narcotic painkiller.
Q. Can Xipra Sublingual tablet be used to treat menstrual cramp?
Xipra Sublingual tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Xipra Sublingual tablet for a migraine?
Xipra Sublingual tablet is not approved for the treatment of migraine. Research studies have shown that Xipra Sublingual tablet is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Xipra Sublingual tablet effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Xipra Sublingual tablet as the cause of back pain can be different for different person.
Q. Is Xipra Sublingual tablet affective in gout management?
Yes. Xipra Sublingual tablet can be given for the treatment of acute gout. Research studies have shown Xipra Sublingual tablet to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Xipra Sublingual tablet?
Yes. You can donate blood when on Xipra Sublingual tablet. Do inform your doctor before donating blood.
Q. Can I use Xipra Sublingual tablet if I am a diabetic?
Xipra Sublingual tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Xipra Sublingual tablet so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Xipra Sublingual tablet if I have a deranged renal function?
No. Xipra Sublingual tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Xipra Sublingual tablet lead to skin reactions?
Yes. Xipra Sublingual tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Xipra Sublingual tablet if I am pregnant?
No. Xipra Sublingual tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Xipra Sublingual tablet if I have peptic ulcer disease?
No. Xipra Sublingual tablet is contraindicated in cases of active peptic ulcer disease. Xipra Sublingual tablet is known to cause gastric ulceration and bleeding.
Q. Can I use Xipra Sublingual tablet if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Xipra Sublingual tablet lead to difficulty in conception?
Yes. Xipra Sublingual tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Xipra Sublingual tablet be used with diuretics?
No. Xipra Sublingual tablet should not be used with diuretics. Xipra Sublingual tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Xipra Sublingual tablet be used with lithium?
No. Xipra Sublingual tablet should not be used with lithium. Xipra Sublingual tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Xipra Sublingual tablet be used with warfarin?
No. Xipra Sublingual tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Xipra Sublingual tablet?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Xipra Sublingual tablet?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Xipra Sublingual tablet?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28.
- PubChem. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:
- ScienceDirect. Piroxicam. [Accessed 02 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Address: S.NO-15,GROUND FLOOR,SHALIMARBAGH,EAST DELHI,DELHI-110088
Country of origin: India
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The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.
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