Phenindione
Written By Dr. Anuj Saini
Reviewed By Dr. Rajeev SharmaLast updated 25 Nov 2025 | 09:34 AM (UTC)
Phenindione Uses
Phenindione is used for deep vein thrombosis, pulmonary embolism, stroke prevention and blood clots. It prevents the formation of blood clots in the legs, lungs, brain or heart.
How Phenindione works
Phenindione is an oral anticoagulant. It acts by preventing the formation of harmful blood clots. Although it does not dissolve the existing blood clots, it inhibits them from growing larger and causing serious problems.
Common side effects of Phenindione
Bleeding
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Expert advice for Phenindione
- Avoid making sudden major changes to your diet during treatment with this medicine.
- Do not consume alcohol while taking Phenindione as this may increase its side effects.
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Phenindione temporarily.
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
- You have been prescribed Phenindione to help prevent blood clots.
- For best results, take it at the same time every day.
- Your doctor may get regular blood tests done to make sure Phenindione is working properly.
- Phenindione increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
- Avoid making sudden major changes to your diet during treatment with this medicine.
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Phenindione temporarily.
- Do not consume alcohol while taking Phenindione as this may increase its side effects.
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Frequently asked questions for Phenindione
Yes, Phenindione increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Phenindione can interact with several medicines. Do not take any medicine without talking to your doctor.
Phenindione reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Phenindione. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.