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Phenindione is used in the treatment and prevention of deep vein thrombosis (dvt) and pulmonary embolus.

How it works

Phenindione is an anticoagulant that prevents the formation of harmful blood clots.

Common side effects


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Expert advice

  • Inform your doctor if you are an elderly, have lost/gained weight, short term illnesses, history of liver/kidney problems, diarrhea, low levels of iron.
  • Inform your doctor if you are undergoing diet changes (changes in intake of Vitamin K fats, oils), or have low level of protein (type S or K); if you have history of stroke or cardiovascular disease, heart disease, major injury, ulcers or bleeding in stomach or intestines, thyroid disorder, cancer, or are going to have surgery.
  • Tell your doctor if you are taking heart medication, medication for dissolving clots or other anticoagulants.
  • You should be regularly monitored with blood tests while on phenindione therapy.
  • Avoid green leafy vegetables and any other food supplements while you are on therapy with phenindione.
  • Seek immediate medical attention if you experience: unusual bleeding or bruising more easily, getting more infections, feeling weak or tired more than usual, jaundice, problems with your kidneys or liver and hair loss.
  • Phenindione is not recommended in children.

Content on this page was last updated on 09 May, 2017, by Dr. Varun Gupta (MD Pharmacology)