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Xapilis 5 Tablet

Apixaban (5mg)
Genuine
Authenticity Assured
Prescription
required
Xapilis 5 Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart. It is used to reduce the risk of stroke and heart attack.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 16 Mar 2026 | 04:08 PM (IST)
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General Information

Contains

Apixaban (5mg)

Marketer

Abbott

Storage

Store below 30°C
The content is shown in English
Xapilis 5 Tablet image
Xapilis 5 Tablet image
Xapilis 5 Tablet image
Xapilis 5 Tablet image
Xapilis 5 Tablet image

Product introduction

Xapilis 5 Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone elective knee or hip replacement surgeries. It can be taken with or without food, and it is best to take it at the same time each day. You may need to take this medicine for many years, even for life in some cases.


Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.


The most common side effect of Xapilis 5 Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include hematoma, anemia, and nausea.


Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding, or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Xapilis Tablet

  • Treatment and prevention of Blood clots

Benefits of Xapilis Tablet

Treatment and prevention of Blood clots
Xapilis 5 Tablet is an anticoagulant used to help prevent the formation of harmful blood clots in the body. It lowers the risk of serious clot-related conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke. It may also be used to reduce the risk of blood clots after certain surgeries. When taken as prescribed, it helps reduce the risk of existing clots worsening and lowers the risk of recurrent clot formation, supporting safer long-term blood flow.

Side effects of Xapilis Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xapilis
  • Hemorrhage
  • Hematoma
  • Bruise
  • Nausea
  • Anemia (low number of red blood cells)

How to use Xapilis Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xapilis 5 Tablet may be taken with or without food.

How Xapilis Tablet works

Xapilis 5 Tablet is a novel oral anticoagulant (NOAC) that helps prevent blood clot formation. It works by directly and selectively inhibiting factor Xa, an important clotting factor involved in thrombin generation. It reduces thrombin formation and helps prevent the development and spread of blood clots.

All substitutes for Xapilis 5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Apigy 5 Tablet

by Cipla Ltd
₹19.7/tablet
9% cheaper
<h3 class=bodySemiBold>Apigy 5 Tablet</h3>

Apigat 5 Tablet

by Natco Pharma Ltd
₹24.4/tablet
13% costlier
<h3 class=bodySemiBold>Apigat 5 Tablet</h3>

Apixapil 5 Tablet

by Alkem Laboratories Ltd
₹11.3/tablet
48% cheaper
<h3 class=bodySemiBold>Apixapil 5 Tablet</h3>

Apixator 5 Tablet

by Torrent Pharmaceuticals Ltd
₹17.2/tablet
20% cheaper
<h3 class=bodySemiBold>Apixator 5 Tablet</h3>

Cadiquis 5mg Tablet

by Cadila Pharmaceuticals Ltd
₹10.3/tablet
52% cheaper
<h3 class=bodySemiBold>Cadiquis 5mg Tablet</h3>

Quick tips

  • Xapilis 5 Tablet can be taken with or without food. Night-time administration is not preferable.
  • It interacts less with food or other medicines. Hence, frequent dose changes are not required.
  • It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects, or engaging in contact sports (e.g., football, wrestling).
  • Informyour doctor if you see blood in your vomit, urine, or stool (black, tarry stools or bright red blood).
  • If you are going to have surgery or dental treatment, you may be asked to stop taking Xapilis 5 Tablet temporarily.
  • Notify your doctor if you have any kidney problems.
  • Do not stop taking medication without talking to your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xapilis 5 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Xapilis 5 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Xapilis 5 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Xapilis 5 Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Xapilis 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Xapilis 5 Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
However, Xapilis 5 Tablet dose adjustment may not be needed in patients with mild liver disease.

Interaction with drugs

Taking Xapilis with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Abciximab (Injection Route)

Do not consume Apixaban with Abciximab. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe

Acenocoumarol (Oral Route)

Do not consume Apixaban with Acenocoumarol. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor and adjust the doses as per the observations.
Severe

Alteplase (Injection Route)

Do not consume Apixaban with Alteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Alteplase may increase the effect of Apixaban.
Severe

Apalutamide (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Apixaban.
Severe

Argatroban (Injection Route)

Do not consume Apixaban with Argatroban. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

Xapilis 5 Tablet is used to reduce the risk of stroke and blood clots in people who have atrial fibrillation. In atrial fibrillation, the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes. Xapilis 5 Tablet also helps to reduce the risk of forming a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery and treat blood clots in the veins of your legs (deep vein thrombosis) or lungs (pulmonary embolism), and reduce the risk of them occurring again.
Xapilis 5 Tablet is generally safe when taken exactly as prescribed, but like all blood thinners, it can increase the risk of bleeding. Do not stop taking it without consulting your doctor, as stopping suddenly may raise the risk of blood clots. In rare cases, people who receive spinal or epidural anesthesia or undergo a spinal puncture while taking this medicine may develop a blood clot around the spine, which can cause serious complications. Always inform your doctor before any such procedure so that appropriate precautions can be taken.
Consult your doctor whether you should stop it or not. It will depend on the type of procedure involved. For instance, if there is a moderate to high risk of bleeding during the procedure, you will have to stop taking Xapilis 5 Tablet 48 hours before surgery.
Xapilis 5 Tablet, when taken more than the recommended dose, may cause unusual bleeding or bruising, red, brown, or pink urine, red or black, tarry stools, and coughing up or vomiting blood or material that looks like coffee grounds. Consult your doctor immediately or seek emergency medical attention in a nearby hospital.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

Oral Factor Xa Inhibitors

References

  1. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelet Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 366-67.
  2. Apixaba [Prescribing Information]n. Princeton, New Jersey: Bristol-Myers Squibb Company; 2012. [Accessed 24 Jan. 2019] (online) Available from:
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Apixaban. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
  4. Apixaban [Prescribing Information]. Verna, Goa, Indoco Remedies Ltd.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
  5. Northwestern Memorial Hospital: Apixaban [Patient Education]. [Accessed 09 Jun, 2023] (online) Available from:
  6. Apixaban [Prescribing Information]. Mumbai, Maharashtra: M/s. Pfizer Limited; 2025.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Xapilis 5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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