Medicine Overview of Wirox Injection
Wirox Injection is used in pain relief
. It relieves pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Wirox Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
In Depth Information on Wirox Injection
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
It should be taken with food or milk to avoid getting an upset stomach.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
Wirox can raise your risk of blood clots, heart attack, or a stroke.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Wirox Injection related warnings
Taking Piroxicam with alcohol may increase your risk of stomach bleeding.
WEIGH RISKS VS BENEFITS
Wirox Injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Wirox Injection is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Wirox Injection may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Wirox Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Wirox Injection may be needed. Please consult your doctor.
No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Wirox Injection should be used with caution in patients with liver disease. Dose adjustment of Wirox Injection may be needed. Please consult your doctor.
If you miss a dose of Wirox Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Wirox Injection
Q. What is the difference between Wirox and diclofenac?
Both Wirox and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Wirox.
Q. What is the difference between Wirox and naproxen?
Both Wirox and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Wirox.
Q. What is the difference between Wirox and meloxicam?
Both Wirox and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Wirox.
Q. What is the difference between Wirox and ketoprofen?
Both Wirox and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Wirox. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Wirox and tramadol?
Wirox is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Wirox and nimesulide?
Both Wirox and nimesulide are pain killers. However, Wirox is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Wirox or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Wirox.
No. Wirox and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Wirox be used along with dexamethasone?
No. Wirox should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Wirox be used with methocarbamol?
Yes. Methocarbamol can be used with Wirox as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Wirox be used along with paracetamol?
Yes. Paracetamol can be used with Wirox as no serious side effects are known. Inform your doctor before starting any of the medication.
Yes. Wirox is a non-steroidal anti-inflammatory drug (NSAID).
Wirox is a sulphur containing compound. Wirox can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
No. Wirox is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
No. Wirox is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
No. Wirox is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
No. Wirox is not a medication to control hypertension. It is important to note that Wirox decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Wirox.
Q. Can Wirox be used along with Losartan?
No. Wirox should not be combined with Losartan. It is important to note that Wirox decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Wirox.
Q. Can Wirox be used with Lisinopril?
No. Wirox should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Wirox.
Q. Can Wirox be used with calcium channel blocker?
Yes. Wirox can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Wirox be used with Tizanidine?
Yes, Wirox can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Yes. Wirox can be combined with beta-cyclodextrin. Research has shown that combining Wirox with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Yes. There are alternatives to Wirox. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
No. Wirox is not a drug to treat allergy. It is a pain killer.
Wirox is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
No. Wirox is not known to cause high. It is a non-narcotic painkiller.
Wirox is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Wirox is not approved for the treatment of migraine. Research studies have shown that Wirox is effective in significantly decreasing the pain associated with migraine without aura.
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Wirox as the cause of back pain can be different for different person.
Yes. Wirox can be given for the treatment of acute gout. Research studies have shown Wirox to be highly effective in the treatment of acute gout.
Yes. You can donate blood when on Wirox. Do inform your doctor before donating blood.
Wirox in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Wirox so taking piroxicam can lead to increased risk of renal failure by many folds.
No. Wirox should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Yes. Wirox is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
No. Wirox should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
No. Wirox is contraindicated in cases of active peptic ulcer disease. Wirox is known to cause gastric ulceration and bleeding.
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Yes. Wirox can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Wirox be used with diuretics?
No. Wirox should not be used with diuretics. Wirox reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Wirox be used with lithium?
No. Wirox should not be used with lithium. Wirox leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Wirox be used with warfarin?
No. Wirox should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Severely interacts with other drugs like
Taking Wirox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Oxyphenbutazone: Sioril
Medicines with composition Nimesulide: Edil, Zelid, Nimusid, Neede, Nimujet, Twinease, Nyci, Nise, Nobel, Nimtus, Spinn, Nimbond, Nimbus, Redynise, Nizer, Denim Juicy, Pyrifen Gel, Hilid P, Nicip, Myonal, Nimtech, Nelsid, Nimusol, Curenim, Biogesic, Nulide, Angip, Nisel TD, NM, Nimeson, Nimutab, Pronim, Nimodol, Nimi Rapi, Relisulide, Nimprex, Zydol, I Nid, Nimdis, Mazic, Emsulide, Nimol, Nugesic, Nimeron, Pyrimide, Nimuvin, Jumolid, Nimeka, Nimotil, Bionim, Nimstal, Arsulide, Lupisulide, Nimusen, Nimcare, Nemu, Nimd, Nimcet, Supernim, Nimind CT, Ginim, Nimpus, Nalgis, Nimlodi, Nimmi, Zega, Unik Junior, Patalgin, Nimtaz, Doly, Numel, Needfast, Nimrod, Pyrestat, Subid, Vylid, Milenim, Nimley, Nixia, Orange N, Nimupain, Gersulide, Nimdus, Doloflam, Knott, Neulab, Nex Kid, Nimik, Nimu, Olnim, Orthogesic, Novolid, Remulide, Nimind, Tremolide, Nimi, Zynimo, Auronim, Novogesic, Nimcell, Sidlide, Nimiz, Eusel, Nimeter, Nmd, Oflapoon, Resinim Plus, Arthorid, Mesulid, Nimaid, Nimcee, Nimdex, Nimobid, Nimoflam, Nimowen, Nimuspa, Niq, Nimulet, Nimisan, Nimrest, Gesnim, Nex MD, Nimopin, Toli, Flenim Plus, Nexmac, Nilide, Nex, Nimus, Nuleb, Pansulide RD, Redfast, Misogesic, Aglonim, Flenim MR, Instanim, Naba P, Nemunac, Nimugee, Spanim, New Nicip, Nimo P, Nimtop, Corfen NS, Mylid, Neosaid, Nimulid, Vylid ID, Nimumac, Minidol, Nilup, Nimek, Nimo, Pirodol, Niltel Fast, Dolonim, Enlide, Pyrisulide, Infanim, Dynalid, Nilpain, Nimecon, Nimutec, Nipace, Resinim, Ortinims, I Nid Aio, Nimace, Nimfast, Soonil, Denim Kid, Actinim, Nimogen, Nimos, Nimular, Geeflam, Kazolid, Numed, Painulide, Nuaid, Dolide, Nimeb, Nimogem, Nimujet Bcd, Nimvista, Nisulid, Aulin, Nimlin, Nimpic, Aurolide, Nicare, Nim, Nimbet, Nimitis, Nimcox, Embulide, Mangolide, Naba, Nemosif, Solide, Flenim, Genlide, Nimjet, Nimuwin, Nise Mdt, Anafebrin, Nimbid, Nimotrin, Nimcet Juicy, Arpinim, Jumolid Kid, Orange N Juicy, Ranter, Pazz, Neopar, Disnim, Nimulet Kid, Nide, Blisulide, Nimsa, Nimucon, Nimuda, Nisul, Nyde, Nimford, Neulite S, Nimopen, Nimez, Nimuflam, Takeaway, Nimtop P, Nimular SP, Denim, Nimica, Nimumed, Nimegesic, Nimotas CD, Nimotas Kid, Zonim, Nam, Ransulide, Nimulex, Neemact, Neosulide, Ladex, Nimax, Nimcart, Trulide, Nimuzen, Nemopar, Megagesic, Zenim, Nimter
Medicines with composition AMINO SALICYLIC ACID: Rexite BT
One of the following vendor pharmacies will deliver Wirox Injection: HPC, RSA, ENP, SGH, UMP, BHP, MAK, JVN, QTM, SBA, RSS, RHW, HGI, EVP, HTS, IAD, OHM, RPI, SLN, IPL, ZEL, WSI, MMS, STA, NVL, MPC, CLT, FGH, BIO, JIV, BMJ, JSL, ZVP, VRS, QLF, DPL, SSA, SHD, ANT, ATL, PWN, SBL, DGN, SRG, PMA, MLC, GBL, KMC, HZF, AGT, PPR, DVH, PTI, AAY, SGC, MDO, SJP, BLE, LCC, PLT, MSD, OWP, GNC, HMP, RDR, HBV, SDM, PNT, 9T9, MDH, HNP, BAP, JVO, SHP, AYM, OLT, DLP, NSL, AMR, AAR, SWA, HEX, HSP, HIP, GTK, HAT, NDP, RUS, RJH, SVH, TFP, SWP, PRN, P2P, TNH, BHM, EQN, NTB, MAX, LHA, RDH, ABP, AYU, DFP, BBS, KHH, BSN, NVY, GPP, PEN, BDN, VDH, SYN, ADT, TOM, ESY, GPT, RWP, VNS, RPP, TRP, NNH, GTC, RHL, ARD, DHR, USF, ATP, OIP, BAL, SHC, GHR, INC, PVP, SCH, WHL, KHC, MAM, SAF, EMB, THP, DYG, RKS, NXG, DPP, BTM