Venflex 37.5 Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Venflex 37.5 Tablet is a medicine used to treat major depressive disorder and anxiety disorders. It helps improve mood, reduce nervousness, and improve overall well-being by restoring the balance of certain brain chemicals that affect mood and emotions.

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General Information

Contains

Venlafaxine (37.5mg)

Marketer

Mediez Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Venflex 37.5 Tablet should be taken with food. Take this medicine at the same time each day to maintain a stable level in your blood. If you miss a dose, take it as soon as you remember. Do not skip doses, and complete the full course of treatment even if you feel better. Do not stop taking this medication abruptly, as it may worsen your symptoms.

Some common side effects of this medicine include nausea, insomnia (difficulty sleeping), constipation, increased sweating, and sexual dysfunction. However, these side effects are temporary and typically resolve on their own over time. Consult your doctor if these do not subside or bother you.

Venflex 37.5 Tablet may cause dizziness and drowsiness, so avoid driving or engaging in activities that require mental focus until you understand how this medicine affects you. Before taking Venflex 37.5 Tablet, inform your doctor if you have any kidney, heart, or liver conditions or a history of seizures (epilepsy or fits). Additionally, notify your doctor if you experience any unusual mood or behavioral changes, worsening depression, or suicidal thoughts. Pregnant and breastfeeding women should consult before taking this medicine, as it may cause harmful effects on the developing baby.

Uses of Venflex Tablet

Benefits of Venflex Tablet

Depression
Venflex 37.5 Tablet is used to treat depression by improving mood-regulating chemicals in the brain. It helps restore emotional balance, reducing feelings of sadness, hopelessness, and fatigue. Improving energy levels and motivation helps to regain interest in daily activities and improves overall well-being.

Anxiety disorder
Venflex 37.5 Tablet helps manage anxiety disorders by balancing neurotransmitters in the brain, particularly serotonin and norepinephrine. It reduces excessive worry, restlessness, and nervousness, helping individuals feel calmer and more in control.

Side effects of Venflex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Venflex

Nausea
Constipation
Increased sweating
Sexual dysfunction
Dizziness
Decreased appetite
Erectile dysfunction

How to use Venflex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Venflex 37.5 Tablet should be taken with or after food.

How Venflex Tablet works

Venflex 37.5 Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline). These are natural substances in the brain that help maintain mental balance and manage depression and anxiety.

All substitutes for Venflex 37.5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Enafaxin 37.5 Tablet

by Zeelab Pharmacy Pvt Ltd

₹0.75/tablet

84% cheaper

Quick tips

It may take 2 to 4 weeks for Venflex 37.5 Tablet to start working. Keep taking it as prescribed.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Venflex 37.5 Tablet, as it may cause excessive drowsiness and increase the risk of liver damage.
It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
Consult your doctor if you experience sudden mood changes or have suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Venflex 37.5 Tablet

Pregnancy

CONSULT YOUR DOCTOR

The safety of Venflex 37.5 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Venflex 37.5 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Babies should be monitored for excessive sleepiness and adequate weight gain.

Driving

UNSAFE

Venflex 37.5 Tablet may cause side effects that could affect your ability to drive.
Venflex 37.5 Tablet may cause dizziness, confusion, and eyesight changes such as blurred vision, which may affect your ability to drive.

Kidney

CAUTION

Venflex 37.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Venflex 37.5 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Venflex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Domperidone (Oral Route)

Do not consume Venlafaxine with Domperidone.

Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Venlafaxine. If concurrent use is essential, please consult your doctor.

Life-threatening

Zolmitriptan (Nasal Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.

Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Venlafaxine. If Tranylcypromine is essential, ensure a gap of at least 1 week after discontinuing Venlafaxine. Please consult your doctor. Please consult your doctor.

Frequently asked questions

Can Venflex 37.5 Tablet cause sedation?

Yes. Venflex 37.5 Tablet can cause sedation. You should inform your doctor if you are taking any other sleep-inducing medicines before starting Venflex 37.5 Tablet.

Is Venflex 37.5 Tablet a psychotropic drug?

Yes. Venflex 37.5 Tablet is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Is Venflex 37.5 Tablet a narcotic?

No. Venflex 37.5 Tablet is not a narcotic drug. Narcotics are drugs with sleep-inducing properties, usually derivatives of opium, like heroin and morphine.

Can I take mirtazapine along with Venflex 37.5 Tablet?

No. There can be a serious side effect when mirtazapine is taken with Venflex 37.5 Tablet. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Can I take Venflex 37.5 Tablet with citalopram?

No. Citalopram and Venflex 37.5 Tablet both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

What is the relation between Venflex 37.5 Tablet and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Venflex 37.5 Tablet from the brain. Some studies have shown that Venflex 37.5 Tablet and its metabolite inhibit the p-glycoprotein.

Can Venflex 37.5 Tablet cause high blood pressure?

Venflex 37.5 Tablet treatment is associated with sustained increases in blood pressure in some people. It is recommended that people who are being treated with Venflex 37.5 Tablet should have regular monitoring of blood pressure. For such people, either dose reduction or discontinuation should be considered.

Can Venflex 37.5 Tablet cause constipation?

Yes. Venflex 37.5 Tablet is known to cause constipation in some patients. Take a fiber-rich diet and drink plenty of water. You may consider taking laxatives as well. Your doctor will suggest ways to prevent or manage it. Please consult your doctor if it does not resolve or gets worse.

Can Venflex 37.5 Tablet cause weight loss?

Yes. Venflex 37.5 Tablet is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Venflex 37.5 Tablet for several weeks. Please consult your doctor if it bothers you.

Can Venflex 37.5 Tablet cause addiction?

No. Venflex 37.5 Tablet does not have habit-forming potential.

Can I take Venflex 37.5 Tablet tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Can gabapentin be given along with Venflex 37.5 Tablet?

Yes, gabapentin can be given with Venflex 37.5 Tablet, but only with a consultation with a doctor. They both, when given together, cause an increase in drowsiness, sleepiness, and decreased concentration at work. Take it with caution.

Can fibromyalgia be treated with Venflex 37.5 Tablet?

Venflex 37.5 Tablet is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Venflex 37.5 Tablet in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Can nerve pain be treated with Venflex 37.5 Tablet?

Venflex 37.5 Tablet is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Why does Venflex 37.5 Tablet cause loss of appetite?

Venflex 37.5 Tablet is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

What are good alternatives to Venflex 37.5 Tablet, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence, talk to your doctor, and then you can have another drug. Do not stop Venflex 37.5 Tablet by yourself, it can lead to increased adverse effects.

Fact Box

Chemical Class

Anisoles

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)

References

Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
Venlafaxine [FDA Label]. Marietta, GA: Urban Pharmaceuticals Inc.; 1993 [revised Jun. 2014]. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Venlafaxine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Venlafaxine hydrochloride [Drug Label]. Pfizer; 2021. [Accessed 18 Feb. 2025] (online) Available form:
Venlafaxine Extended-Release [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2017. [Accessed 18 Feb. 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mediez Pharma
Address: SHOP NO. 5, MEDICINE MARKET, ADJOINING GURU TEG BHADUR MARKET, SIRSA HR 125055 IN , - , .

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Venflex 37.5 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Venflex Tablet

Benefits of Venflex Tablet

Side effects of Venflex Tablet

How to use Venflex Tablet

How Venflex Tablet works

All substitutes for Venflex 37.5 Tablet

Enafaxin 37.5 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Domperidone (Oral Route)

Tapentadol (Nasal Route)

Moclobemide (Oral Route)

Zolmitriptan (Nasal Route)

Tranylcypromine (Oral Route)

Frequently asked questions

Can Venflex 37.5 Tablet cause sedation?

Is Venflex 37.5 Tablet a psychotropic drug?

Is Venflex 37.5 Tablet a narcotic?

Can I take mirtazapine along with Venflex 37.5 Tablet?

Can I take Venflex 37.5 Tablet with citalopram?

What is the relation between Venflex 37.5 Tablet and p-glycoprotein?

Can Venflex 37.5 Tablet cause high blood pressure?

Can Venflex 37.5 Tablet cause constipation?

Can Venflex 37.5 Tablet cause weight loss?

Can Venflex 37.5 Tablet cause addiction?

Can I take Venflex 37.5 Tablet tablet instead of a capsule?

Can gabapentin be given along with Venflex 37.5 Tablet?

Can fibromyalgia be treated with Venflex 37.5 Tablet?

Can nerve pain be treated with Venflex 37.5 Tablet?

Why does Venflex 37.5 Tablet cause loss of appetite?

What are good alternatives to Venflex 37.5 Tablet, particularly when a side effect is reduced sex drive?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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