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Velfex 37.5mg Tablet

Prescription Required

Overview

Introduction

Velfex 37.5mg Tablet is a prescription medicine used in the treatment of depression and anxiety disorder. Due to its powerful sedative activity, this medicine is also useful for people who have difficulty in falling asleep due to depression.

Velfex 37.5mg Tablet helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that maintains mental balance. It is taken by mouth with food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. If you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as it may worsen your symptoms.

Some common side effects of this medicine includes nausea, vomiting, and insomnia (difficulty in sleeping). Monitor your blood pressure regularly while taking this medicine as it may cause an increase in blood pressure, especially during the first month of treatment. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may also cause weight loss, consult a dietitian for dietary supplement or try to increase your food portion. It is important to inform doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of Velfex Tablet

Side effects of Velfex Tablet

Common
  • Nausea
  • Vomiting
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Decreased appetite
  • Anxiety
  • Constipation
  • Increased sweating
  • Sexual dysfunction

How to use Velfex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Velfex 37.5mg Tablet is to be taken with food.

How Velfex Tablet works

Velfex 37.5mg Tablet works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Velfex 37.5mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Velfex 37.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Velfex 37.5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Babies should be monitored for excessive sleepiness and adequate weight gain.
Driving
UNSAFE
Velfex 37.5mg Tablet may cause side effects which could affect your ability to drive.
As side effects of Velfex 37.5mg Tablet are dizziness, confusion and eye sight changes such as blurred vision and this may affect your ability to drive.
Kidney
CAUTION
Velfex 37.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Velfex 37.5mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Velfex 37.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Velfex 37.5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Velfex Tablet?

If you miss a dose of Velfex 37.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Velfex 37.5mg Tablet
₹3.9/Tablet
Nutraport 37.5mg Tablet
Teknovations Life Science
₹8.4/Tablet
115% costlier
₹4.6/Tablet
18% costlier
₹4.9/Tablet
26% costlier
Venx 37.5mg Tablet
Psycogen Captab
₹4.9/Tablet
26% costlier
Venflex 37.5 Tablet
Mediez Pharma
₹5.5/Tablet
41% costlier

Quick Tips

  • Velfex 37.5mg Tablet helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Velfex 37.5mg Tablet to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Velfex 37.5mg Tablet as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Velfex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Lizolan, Lidoford, Mapzolide
LIFE-THREATENING
Brand(s): Trima, Rimarex, Morex
LIFE-THREATENING
Brand(s): Rasalect, Relgin, Rasipar
LIFE-THREATENING
Brand(s): Jumex
LIFE-THREATENING

Patient Concerns

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Hello sir, I have been taking tablets for anxiety and depression for last one year. Gradually my doctor decreased dosage. Now iam using stresloc, Opiprol(antidepressant), and Alzolam 0.5. With capi gold vitamin tablet.I have generalised anxiety disorder. Six days ago I dint take that stresloc tablet. It's a combination of alprazolam and propranolol. And it's for morning and night. I decided to skip the morning dosage. First day I dint feel anything. But I couldn't sleep well. Second day I was feeling migraine in head. Anxiety has increased. On that day night I felt there was a fluid running in my head. At that same time , I heard some insect sounds coming from my head. It means insects are produced sound at night time and it's pitch level is high. That sound disturbed me a lot and my concentration was always on that. Before that incident I was watching movie through headphone with full sound in my mobile. I always used to watch movies or videos using headphone with full sound . After that incident I used to take that morning dosage also. Anxiety has controlled but still that ringing sound disturbed at some time . Not all time. My question is that ringing sound produced by any ear problem or that anxiety effects. Plz reply fast ly bcoz it affects my concentration Is that ear problem or anxiety effects??
Dr. Vijay Verma
Ear Nose Throat Specialist
See both ear and anxiety issues can cause ringing better get audiometry test if it is normal than ringing is due to anxiety
Having anxiety disorder and depression for the last 4 yrs undergone course for the same but symptoms persist and now having more negative feelings now taking peroxtine release and cloanezapam tablet daily night Suggest cure in homeopath.
Dr. Saurav Arora
Homeopathy
In your case I advise you to visit a homeopathic doctor and take treatment under supervision. In homeopathy symptoms, history and examination is very important. In majority of cases, after a long case taking and case workout, we try to select a constitutional remedy which is used to treat the disease from its root cause. Taking a constitutional treatment shall also take care the reoccurrence of disease.
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Do you have any questions related to Velfex 37.5mg Tablet ?

FAQs

Q. Is Velfex a mood stabiliser?

No. Velfex is not approved as a mood stabiliser. It is used in the treatment of depression and anxiety disorder.

Q. Can Velfex cause sedation?

Yes. Velfex can cause sedation. You should inform your doctor if you are taking any other sleep inducing medicines before starting Velfex.

Q. Can I use Velfex as a painkiller?

No. Velfex is not a pain killer. It is used in the treatment of depression and anxiety disorder.

Q. Is Velfex a psychotropic drug?

Yes. Velfex is a psychotropic drug. Any medication capable of affecting the mind, emotions, and behaviour are called psychotropic drugs.

Q. Can I take Velfex twice a day?

Yes. The dosage schedule should be decided by the doctor depending on the type of disorder.

Q. Is Velfex a narcotic?

No. Velfex is not a narcotic drug. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Can I take vitamin B complex along with Velfex?

Yes. Velfex can be taken with B complex vitamins. There are no known major interactions between these medications.

Q. Can I take Velfex with my Hepatitis B vaccination?

Yes. Velfex can be taken with hepatitis B vaccination. There are no known major interactions between these two medications. Consult your doctor before starting any medication or therapy while taking Velfex.

Q. Can I take Velfex with my Hepatitis C vaccination?

There are no known brands of hepatitis C vaccines in India. Consult your doctor before starting any medication or therapy while taking Velfex

Q. What is the Cmax of Velfex?

After taking immediate-release Velfex tablets, the peak plasma concentrations of Velfex is seen in 2 hours.

Q. Can Velfex get high?

No. Velfex is not known to cause high.

Q. Can Velfex cause weight gain?

No. Studies have shown Velfex causes weight loss when taken for several weeks.

Q. What is the half-life of Velfex?

The plasma half-life of Velfex is 5±2 hours.

Q. What is the difference between Velfex ER and XR?

Both are same medication. Velfex ER and XR both means extended release preparation which releases the medication slowly into the body and maintains a constant needed medications levels. The advantage of taking ER/XR tablets is the frequency of dosage can be decreased.

Q. Can I take mirtazapine along with Velfex?

No. There can be a serious side effect when mirtazapine is taken with Velfex. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can I take Velfex with citalopram?

No. Citalopram and Velfex both increase serotonin levels. Avoid or use any alternate drug. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can I take Velfex with sertraline?

No. Sertraline can not be taken with Velfex as it increases serotonin levels. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can I take Velfex with duloxetine?

No. Duloxetine can not be taken with Velfex as it causes a serious increase in serotonin levels. This can lead to a potentially life-threatening condition called as serotonin syndrome.

Q. What is the relation between Velfex and p-glycoprotein?

P-glycoprotein is responsible for the expulsion of Velfex from the brain. Some studies have shown that Velfex and its metabolite inhibit the p-glycoprotein.

Q. Where is Velfex absorbed?

Velfex is absorbed from the intestine after being metabolised by the liver.

Q. When does Velfex expire?

The expiry date of Velfex is given on the tablet strip and provided by the manufacturer.

Q. When does Velfex produce the effect?

It takes time for Velfex to work and it depends from person to person.

Q. When should I take Velfex?

Velfex is a medication to treat generalised depressive disorder or depression. Consult your doctor before taking this medication.

Q. Which is the best time to take Velfex?

It depends on the type of tablet. If it is Velfex XR then it can be taken once daily else the daily dosage is divided into 2-3 times.

Q. Can Velfex cause high blood pressure?

Velfex treatment is associated with sustained increases in blood pressure in some patients. It is recommended that patients receiving Velfex should have regular monitoring of blood pressure. For patients who experience a sustained increase in blood pressure while receiving Velfex, either dose reduction or discontinuation should be considered.

Q. Can Velfex cause constipation?

Yes. Velfex is known to cause constipation in some patients.

Q. Can Velfex cause sweating?

Yes. Velfex is known to increase sweating in some patients.

Q. Can Velfex cause weight loss?

Yes. Velfex is known to cause weight loss in some patients. In research studies, a dose-dependent weight loss was noted in patients treated with Velfex for several weeks.

Q. Can Velfex cause addiction?

No. Velfex does not have habit-forming potential.

Q. Can I take Velfex tablet instead of a capsule?

You can take a tablet instead of the capsule but only under consultation or prescription of a doctor. You should not change it yourself as the different formulation of a medication may have a different action as drug release would be different in both. This can lead to an inappropriate treatment and may lead to side effects or even failure of treatment.

Q. Can I use phentermine with Velfex?

No. Phentermine can not be taken with Velfex as it increases serotonin levels. It can cause a serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Can gabapentin be given along with Velfex?

Yes. Gabapentin can be given with Velfex but only with a consultation of a doctor. They both, when given together, causes an increase drowsiness, sleepiness and decreased concentration in work. Take with caution.

Q. Can I take tramadol along with Velfex?

No. Tramadol should be absolutely avoided with Velfex. They both cause an increase in the levels of serotonin in the body increasing the chances of potentially life-threatening serotonin syndrome.

Q. What is the difference between Velfex and desvenlafaxine?

Desvenlafaxine is an active metabolite of Velfex. It is the same medication in an active form.

Q. Can fibromyalgia be treated with Velfex?

Velfex is not approved for the treatment of fibromyalgia. Some research studies have shown promising results of Velfex in the treatment of fibromyalgia. Consult your doctor before starting this medication.

Q. Can I take citalopram in place of Velfex?

Both Citalopram and Velfex are anti-depressants but their action is different. Citalopram results in an increase in the serotonin levels but venlafaxine increases many other neurotransmitters apart from serotonin. Consult your doctor before changing the medication.

Q. Can depression be treated with Velfex?

Yes. Velfex is a medication for the treatment of depression.

Q. Can I use Velfex for anxiety disorder?

Yes. Velfex can be used for the treatment of anxiety disorder.

Q. Can I use Velfex for a tension headache?

No. Velfex is not approved for the treatment of a tension headache. It is used in the treatment of depression and anxiety disorder.

Q. Can nerve pain be treated with Velfex?

Velfex is not approved for treatment of nerve pain disorders but some researchers have proved its efficacy in nerve pain. It is currently used off-label for nerve pain.

Q. Can I use Velfex for a migraine?

Velfex is not approved for treatment of a migraine but some researchers have proved its efficacy in the prophylaxis of a migraine. It is currently used off label for migraine.

Q. Can hot flashes be treated with Velfex?

Velfex is not approved for treatment of hot flashes. It is used in the treatment of depression and anxiety disorder.

Q. Which medication is best, Buspirone or Velfex?

Buspirone is an anxiolytic drug given for treatment of generalised anxiety disorder. Velfex is an antidepressant drug. Buspirone can be added to Velfex to augment the effect of Velfex. But this can lead to a potentially serious condition called as serotonin syndrome. It is a potentially life-threatening can present as agitation, hallucinations, nausea, vomiting, diarrhoea, tachycardia, labile blood pressure, hyperthermia and coma.

Q. Why does Velfex cause loss of appetite?

Velfex is known to cause changes in the neurotransmitters levels and chemicals in the brain which leads to decrease in appetite and this loss of appetite is dose dependent.

Q. Can Velfex be switched to desvenlafaxine abruptly?

No. You should not change or switch over to any other drug. It may lead to various adverse effects called as discontinuation symptoms. Talk to your doctor if you are not comfortable with Velfex and it should be tapered slowly and then stopped.

Q. What are good alternatives to Velfex, particularly when a side effect is reduced sex drive?

If you find any side effects like decreased sex drive or impotence talk to your doctor and then you can have some other drug. Do not stop Velfex by yourself it can lead to increased adverse effects.

Q. Am I dizzy because I stopped taking Velfex?

Yes. Dizziness can be due to Velfex. Velfex therapy leads to increased blood pressure so abrupt stoppage can lead to decreased blood pressure and can cause dizziness.

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References
  1. Stahl SM, editor. Venlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 721-26.
  2. DeBattista C. Antidepressant Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 513.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1466.
  4. Venlafaxine.Marietta, USA:Kremers Urban Pharmaceuticals Inc.;1993[revised 06-2014]. [Accessed 19 Mar. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Venlafaxine. [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
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