Product introduction
Vblastin 10mg Injection is an anti-cancer medication used in the treatment of breast cancer, kidney cancer, Hodgkin’s disease, and Non-Hodgkin's lymphoma.
Vblastin 10mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, and decreased appetite. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You should take precautions while taking this medication as it may cause inflammation of mouth and lips and neurological toxicity.
Uses of Vblastin Injection
Benefits of Vblastin Injection
In Breast cancer
Breast cancer occurs when abnormal cells grow uncontrollably in breast tissue and may spread to other parts of the body. Vblastin 10mg Injection helps slow the growth and spread of these cancer cells, supporting better disease control. Its use as part of combination therapy can help improve treatment response and overall disease management.
In Kidney cancer
Kidney cancer develops when abnormal cells affect kidney tissue and disrupt normal kidney function. Vblastin 10mg Injection helps limit the multiplication of cancer cells, which can slow disease progression. This supports better control of symptoms and overall treatment outcomes.
In Hodgkin’s disease
Hodgkin’s disease is a cancer of the lymphatic system that affects the body’s ability to fight infections. Vblastin 10mg Injection helps reduce the number of abnormal lymph cells, supporting disease control. This can help achieve remission and improve long-term management when used with other anticancer medicines.
In Non-Hodgkin lymphoma (NHL)
Non-Hodgkin’s lymphoma is a group of blood cancers that cause uncontrolled growth of lymphocytes in lymph nodes and other organs. Vblastin 10mg Injection helps slow the spread of cancer cells, supporting better control of the disease. This helps improve treatment effectiveness and overall patient outcomes as part of combination therapy.
Side effects of Vblastin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vblastin
- Hair loss
- Constipation
- Decreased white blood cell count (lymphocytes)
- High blood pressure
- General discomfort
- Bone pain
- Tumor pain
- Jaw pain
How to use Vblastin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vblastin Injection works
Vblastin 10mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Vblastin 10mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Vblastin 10mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Vblastin 10mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Vblastin 10mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Vblastin 10mg Injection in patients with kidney disease. Please consult your doctor.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Vblastin 10mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Vblastin 10mg Injection may not be advised in patients with severe liver disease.
Use of Vblastin 10mg Injection may not be advised in patients with severe liver disease.
What if you forget to take Vblastin Injection?
If you miss a dose of Vblastin 10mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Vblastin 10mg Injection
₹223/Injection
Chemoblast 10mg Injection
Neon Laboratories Ltd
₹266.5/injection
18% costlier
Quick tips
- Vblastin 10mg Injection is given as an IV infusion or injection into a vein under the supervision of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood cell count, platelet count, uric acid level and liver function.
- Inform your doctor if you experience a skin rash, swelling of face or lips and trouble breathing.
Fact Box
Chemical Class
Vinca alkaloids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Microtubule Dynamics Inhibitors- Vinka Alkaloids
Interaction with drugs
Taking Vblastin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vinblastine.
Concurrent use may cause hairloss, drop in blood cell counts,
Concomitant use is not recommended. Please consult with your doctor. Azithromycin may raise blood levels of Vinblastine.
Concurrent use may cause hairloss, drop in blood cell count
Do not consume Filgrastim from 24 hours before or 24 hours after taking Vinblastine. Vinblastine may reduce the efficacy of Filgrastim.
Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vinblastine.
Concurrent use may cause hairloss, drop in blood cell counts,
Concomitant use is not recommended. Please consult with your doctor. Azithromycin may raise blood levels of Vinblastine.
Concurrent use may cause hairloss, drop in blood cell count
Patient concerns
FAQs
Is Vblastin 10mg Injection a vesicant?
Vblastin 10mg Injection is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly.
How is Vblastin 10mg Injection administered?
Vblastin 10mg Injection is administered by intravenous route only.
Does Vblastin 10mg Injection cause hair loss/infertility?
Yes, Vblastin 10mg Injection may cause hair loss/infertility.
How does Vblastin 10mg Injection prevent mitosis?
Vblastin 10mg Injection prevents mitosis by inhibition of microtubule formation.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1706.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 949.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1476-77.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Vinblastine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Marketer details
Name: Chandra Bhagat Pharma Pvt Ltd
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Country of origin: India
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