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Vancofit 500mg Injection 1
Vancofit 500mg Injection 2
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Vancofit 500mg Injection

Vancomycin (500mg)
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Product Summary :

Vancofit 500mg Injection is an intravenous glycopeptide antibiotic used to treat serious infections caused by susceptible Gram-positive bacteria. It blocks bacterial cell-wall formation, causing bacteria to die. It is given slowly into a vein by a healthcare professional. Kidney function and vancomycin levels may need regular monitoring during treatment.


Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 04 Nov 2026 | 07:57 PM (IST)
₹277 MRP ₹311.2511% off 
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General Information

The content is shown in English
Vancofit 500mg Injection 1
Vancofit 500mg Injection 2

Product introduction

Vancofit 500mg Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others.

Vancofit 500mg Injection is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath, or itching. It may also be combined with other antibiotics to treat additional types of bacteria.

Some people may develop wheezing, hives, flushing (sense of warmth in the face, ears, neck, and trunk), and Pain and muscle spasm of the chest and back.

Inform your doctor if you have a history of an allergic reaction to this medication in the past. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Some people may be advised blood tests to check the level of this medicine in their blood. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Uses of Vancofit Injection

  • Treatment of Severe bacterial infections

Benefits of Vancofit Injection

Treatment of Severe bacterial infections
Vancofit 500mg Injection is an antibiotic used to treat serious infections caused by susceptible Gram-positive bacteria, including certain infections of the blood, heart, lungs, skin, soft tissues and bones. It helps stop bacterial growth and allows the body's immune system to fight the infection.

Side effects of Vancofit Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vancofit
  • Nausea
  • Kidney damage
  • Hearing loss
  • Ringing in ear
  • Decreased white blood cell count (neutrophils)
  • Phlebitis
  • Hypotension (low blood pressure)
  • Fever
  • Chest pain
  • Back pain
  • Skin reaction

How to use Vancofit Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Vancofit Injection works

Vancofit 500mg Injection works by blocking the formation of the bacterial cell wall, which bacteria need to survive. This weakens the cell wall and causes susceptible bacteria to die.

Dosage

Vancofit 500mg Injection is administered as an intravenous infusion by a healthcare professional. The dose and dosing interval are individualised according to the type and severity of infection, body weight, kidney function, age and vancomycin blood levels, where monitoring is required. The medicine is generally infused over at least 60 minutes to reduce the risk of infusion-related reactions. Do not administer it yourself or change the dose or infusion rate.

Quick tips

  • You  have been prescribed Vancofit 500mg Injection to treat serious bacterial infections of the heart, blood, bones, and soft tissues.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • It should be taken slowly via a drip. Fast infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching.
  • Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine.
  • Your doctor may get regular blood tests done to check the level of this medicine in your blood.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Vancofit 500mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Vancofit 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Vancofit 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Vancofit 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Vancofit 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test and some blood tests is advised while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Vancofit 500mg Injection in patients with liver disease.

Interaction with drugs

Taking Vancofit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Amikacin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Amphotericin B (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Amphotericin B (Vaginal Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Cisplatin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Colistin Sulphate (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.

Frequently asked questions

Vancofit 500mg Injection is an antibiotic used to treat serious infections caused by susceptible Gram-positive bacteria. Depending on the infection and the bacteria involved, it may be used for infections of the blood, heart, lungs, skin, soft tissues and bones. It is often used when resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), are suspected or confirmed.
Vancofit 500mg Injection can cause an infusion-related reaction if it enters the bloodstream too quickly. This reaction may cause redness or flushing of the face and upper body, itching, rash, chest or back pain, muscle spasms or low blood pressure. Giving the medicine slowly, usually over at least 60 minutes, helps reduce this risk. The infusion rate may be adjusted by the healthcare professional according to the dose and the patient's condition.
A vancomycin infusion reaction is a reaction that may occur during or shortly after the infusion, particularly when the medicine is given too quickly. It can cause flushing, itching, redness over the face, neck and upper body, chest or back discomfort and muscle spasms. It is not always a true allergy, but it should be reported immediately. The healthcare professional may stop or slow the infusion and provide treatment depending on the symptoms.
Vancofit 500mg Injection is mainly removed from the body through the kidneys. If kidney function decreases, the medicine can build up in the body and increase the risk of side effects, including kidney injury and hearing problems. Your doctor may check blood tests such as serum creatinine and adjust the dose or dosing interval according to your kidney function.
Yes. In some patients, Vancofit 500mg Injection may cause hearing-related problems, such as ringing in the ears, dizziness or hearing loss. The risk may be higher with high drug exposure, kidney problems, older age or use of other medicines that can affect hearing. Inform your doctor promptly if you notice ringing in the ears, reduced hearing or unusual dizziness during treatment.
Yes. Vancofit 500mg Injection may cause kidney injury, particularly when blood levels become too high, treatment is prolonged, kidney function is already reduced or it is used with other medicines that can affect the kidneys. Your doctor may monitor kidney function and vancomycin levels and adjust treatment when needed. Inform your healthcare team if you notice a marked decrease in urine output.
Yes. In some serious infections, Vancofit 500mg Injection may be combined with other antibiotics to cover bacteria that it does not act against or to provide a specific combination treatment. However, some combinations may increase the risk of kidney injury or other adverse effects. Tell your doctor about all antibiotics and other medicines you are receiving so that the combination can be monitored appropriately.
Do not stop or change treatment on your own, even if you start feeling better. The duration depends on the type of infection, the bacteria causing it and your response to treatment. Your doctor will decide when treatment can be stopped or changed. Stopping too early may result in the infection not being adequately treated.
Inform your doctor if you have kidney disease, hearing problems or a previous allergic reaction to vancomycin. Also mention all medicines you are receiving, especially other antibiotics, medicines that may affect kidney function or hearing, and anaesthetic medicines. This information helps your doctor select an appropriate dose and monitor for possible interactions or adverse effects.
Seek immediate medical attention if you develop difficulty breathing, severe wheezing, swelling of the face or throat, fainting or a severe drop in blood pressure. A new rash with blisters, peeling skin or sores in the mouth or eyes may indicate a serious skin reaction and also requires urgent assessment. Do not wait for the next scheduled dose or review if these symptoms occur.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Glycopeptides

Related lab tests

References

  1. MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1539-42.
  2. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 786-87.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1459-60.
  4. ScienceDirect. Vancomycin. [Accessed on 26 Mar. 2019] (online) Available from:
  5. Vancomycin. Deerfield, IL: Baxter Healthcare Corporation; 2008. [Accessed 28 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
  7. Vancomycin. Deerfield, IL: Baxter Healthcare Corporation; 2008. [Accessed 28 Mar. 2019] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kalmia Healthcare
Address: SCO 218,First Floor, Phase I, Urban Estate, Patiala, Punjab 147002

Vendor Details

Country of origin: India
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