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Valprodex 250 SR Tablet

Valproic Acid (250mg)
Genuine
Authenticity Assured
Prescription
required
Valprodex 250 SR Tablet is used to treat epilepsy (seizures). It has a calming effect on the brain by relaxing the nerves.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 21 Apr 2026 | 02:00 PM (IST)
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General Information

The content is shown in English
Valprodex 250 SR Tablet image
Valprodex 250 SR Tablet image
Valprodex 250 SR Tablet image

Product introduction

Valprodex 250 SR Tablet may be taken with or without food, preferably at the same time, each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. Never skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it abruptly without discussing it with your doctor, as it may increase seizure frequency.

Some of the common side effects of this medicine include headache, blurred vision, loss of appetite, nausea, vomiting, hair loss, and diarrhea. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


Regular liver function monitoring is recommended while taking Valprodex 250 SR Tablet. It is contraindicated in individuals with known hypersensitivity, significant hepatic impairment, or certain mitochondrial disorders. Use during pregnancy is not recommended due to the risk of harm to the unborn baby. Caution is also advised in patients with a history of pancreatitis or bleeding disorders. If symptoms such as persistent vomiting, abdominal pain, unusual bleeding, or jaundice occur, seek medical attention promptly.

Uses of Valprodex Tablet ER

Benefits of Valprodex Tablet ER

Epilepsy/Seizures
Valprodex 250 SR Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Valprodex Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Valprodex
  • Hair loss
  • Blurred vision
  • Memory loss
  • Weakness
  • Abnormality of voluntary movements
  • Bronchitis (inflammation of the airways)
  • Diarrhea
  • Double vision
  • Dizziness
  • Breathlessness
  • Ecchymosis (discoloration of the skin resulting from bleeding underneath)
  • Emotional lability
  • Fever
  • Flu-like symptoms
  • Headache
  • Increased appetite
  • Nausea
  • Nervousness
  • Peripheral edema
  • Inflammation of the nose
  • Drowsiness
  • Altered thinking
  • Low blood platelets
  • Ringing in ear
  • Tremors
  • Vomiting
  • Weight gain
  • Weight loss

How to use Valprodex Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valprodex 250 SR Tablet should be taken with or after food.

How Valprodex Tablet ER works

Valprodex 250 SR Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause cosmetic side effects such as increased hair growth on the face, acne and thinning of hair. Talk to your doctor if this bothers you.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Valprodex 250 SR Tablet
Pregnancy

Pregnancy

UNSAFE
Valprodex 250 SR Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Valprodex 250 SR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Valprodex 250 SR Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Valprodex 250 SR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Valprodex 250 SR Tablet is not recommended in patients with severe liver disease and active liver disease.

Interaction with drugs

Taking Valprodex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Chlorpromazine (Oral Route)

Your doctor may monitor your liver function regularly.
Moderate

Chlorpromazine (Injection Route)

Your doctor may monitor your liver function regularly.
Moderate

Apalutamide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Apalutamide may reduce blood levels of Valproic Acid.
Mild

Oxcarbazepine (Oral Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.
Mild

Aspirin (Oral Route)

Talk to your doctor if you experience nausea, vomiting, or dizziness during the simultaneous use of these medicines.

Frequently asked questions

Valprodex 250 SR Tablet does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.
You should not stop taking Valprodex 250 SR Tablet suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.
Yes, weight gain can occur with the use of Valprodex 250 SR Tablet. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.
Yes, Valprodex 250 SR Tablet does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Valprodex 250 SR Tablet and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Valprodex 250 SR Tablet levels in your blood levels.
Many patients can safely take Valprodex 250 SR Tablet for a long time. Rarely, long-term use of Valprodex 250 SR Tablet may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking Valprodex 250 SR Tablet for a long time, get regular check ups done for bone health.
Valprodex 250 SR Tablet may cause thinning of hair, change of hair colour and even hair loss. If you are concerned talk to your doctor if it is possible to reduce the dose of Valprodex 250 SR Tablet. Your hair may regrow after either reducing your dose or switching to a different medicine.

Fact Box

Chemical Class

Methyl- branched fatty acids

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

References

  1. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 596-98.
  2. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 413-15.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1449-54.
  4. Valporic acid. Barceloneta, PR :AbbVie LTD; 1978 [revised Feb 2016]. [Accessed 19 Mar 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
  6. Valproic acid. Indiana, PA: RemedyRepack Inc.; 2026. [Accessed 21 Apr. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Nuvenex Labs Pvt Ltd
Address: Tuttsan House Survey No.92, Plot No.14,Marigold compound Nr. CRI pump,Khatraj Chowkdi, Taluka Kalol, Dist: Gandhinagar- 382721, Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Valprodex 250 SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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