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V-Dom Oral Solution

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Feb 2026 | 11:55 AM (IST)
V-Dom Oral Solution is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
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V-Dom Oral Solution
V-Dom Oral Solution
bottle of 30 ml Oral Solution
₹35.6
₹39.38
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Same composition
Vomishield Oral Solution
Vomishield Oral Solution
bottle of 30 ml Oral Solution
by Leeford Healthcare Ltd
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General Information

The content is shown in English
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V-Dom Oral Solution image
V-Dom Oral Solution image
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V-Dom Oral Solution image

Product introduction

V-Dom Oral Solution may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.

V-Dom Oral Solution may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.

Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.

Uses of V-Dom Oral Solution

Benefits of V-Dom Oral Solution

Vomiting
Vomiting is the forceful expulsion of stomach contents, often caused by stomach irritation, infections, chemotherapy, or after surgery. V-Dom Oral Solution helps by controlling this symptom, making patients more comfortable and preventing dehydration and weakness.
Nausea
Nausea is the unpleasant feeling of wanting to vomit, commonly linked with motion sickness, medical treatments, or infections. V-Dom Oral Solution eases this feeling, helping patients eat, drink, and recover more comfortably.

Side effects of V-Dom Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of V-Dom
  • Constipation
  • Diarrhea
  • Fatigue
  • Headache

How to use V-Dom Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. V-Dom Oral Solution may be taken with or without food.

How V-Dom Oral Solution works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving V-Dom Oral Solution just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Quick tips

  • V-Dom Oral Solution effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
  • It is fast-acting and starts working within 30 minutes.
  • Practice self-care measures:
    1. Give plenty of fluids to your child to avoid dehydration
    2. Avoid giving fried and spicy food or heavy meals to your child. 
    3. Ensure that your child eats slowly and in small proportions.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with V-Dom Oral Solution does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
V-Dom Oral Solution is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
V-Dom Oral Solution should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
V-Dom Oral Solution does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
V-Dom Oral Solution should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
V-Dom Oral Solution should be used with caution in patients with liver disease. Dose adjustment may be needed.
In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.

Interaction with drugs

Taking V-Dom with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Ondansetron.
Life-threatening

Voriconazole (Oral Route)

Do not consume Voriconazole with Ondansetron.
Life-threatening

Fluconazole (Oral Route)

Do not consume Fluconazole with Ondansetron.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Ondansetron.
Life-threatening

Efavirenz (Oral Route)

Do not consume Efavirenz with Ondansetron.

Frequently asked questions

V-Dom Oral Solution is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give V-Dom Oral Solution to your child to prevent vomiting post-procedure. Apart from this, V-Dom Oral Solution is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving V-Dom Oral Solution to your child for a few days. Stick to the dose for best results.
V-Dom Oral Solution is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of V-Dom Oral Solution can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
V-Dom Oral Solution should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
V-Dom Oral Solution can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting V-Dom Oral Solution. Also, check with your child’s doctor before giving any medicine to your child.
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
Avoid combining V-Dom Oral Solution with such medicines because concomitant use of V-Dom Oral Solution with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

Fact Box

Chemical Class

Carbazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
  4. Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
  5. Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024. [Accessed 25 Jul. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Domagk Smith Labs Pvt Ltd
Address: flot no. 31/36, near salwan public school, old rajinder nagar, new delhi-110060, delhi, india

Vendor Details

Country of origin: India
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