Ulyses 150 Tablet is a medicine used to dissolve certain types of gallstones, to prevent them from forming and to treat a type of liver disease called primary biliary cirrhosis. It is a bile acid which helps break down cholesterol which has formed into stones in your gallbladder.

Ulyses 150 Tablet should be taken after a meal with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. It is best swallowed whole. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear. Even if the gallstones completely dissolve, the treatment should still be continued for several weeks or months.

The most common side effects are diarrhea, stomach upset or pain, nausea, dizziness, back pain or hair loss. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Women who use this medicine for dissolving gallstones should stop using the birth control pill because the hormones in it can increase the production of gallstones. During treatment you may need ultrasound scans, or frequent blood tests to check your liver function.

Uses of Ulyses Tablet

Side effects of Ulyses Tablet

Common

Abdominal pain
Diarrhea
Hair loss
Itching
Nausea
Rash

How to use Ulyses Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ulyses 150 Tablet is to be taken with food.

How Ulyses Tablet works

Ulyses 150 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety Advice

Alcohol

UNSAFE

Ulyses 150 Tablet may cause excessive drowsiness with alcohol.

Pregnancy

SAFE IF PRESCRIBED

Ulyses 150 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breastfeeding

SAFE IF PRESCRIBED

Ulyses 150 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Ulyses 150 Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Ulyses 150 Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Ulyses 150 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Ulyses Tablet?

If you miss a dose of Ulyses 150 Tablet, skip it and continue with your normal schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.

Ulyses 150 Tablet

₹16.37/Tablet

Ursocol 150 Tablet

Sun Pharmaceutical Industries Ltd

₹15.3/Tablet

save 7%

Hepakind 150 Tablet

Mankind Pharma Ltd

₹14.5/Tablet

save 11%

Udihep Tablet

Win-Medicare Pvt Ltd

₹23.8/Tablet

45% costlier

Sorbidiol 150 Tablet

Franco-Indian Pharmaceuticals Pvt Ltd

₹12.51/Tablet

save 24%

Golbi 150 Tablet

Intas Pharmaceuticals Ltd

₹15.9/Tablet

save 3%

View all alternate brands

Quick Tips

Ulyses 150 Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for three months after the start of therapy, and every six months thereafter.
Do not stop taking the medication without talking to your doctor.

Interaction with Drugs

Taking Ulyses with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Cyclosporine

Brand(s): Imudrops, Neoral, Aurosporine

SERIOUS

View all interactions

Patient Concerns

I have liver cirrhosis, fibrosis scan 3.29, taking nusam400, ulyses plus, betacap tr 40, panlipase, benfomet plus & pantocid 40. Please recommend the medicine.

Dr. Pawan Rawal

Gastroenterologist

Need to see a gastroenterologist

sir, my father 61 years old man,have liver cirrhosis ,middle stage now using golbi 300mg tablet daily 2times , i want to know whether any problem if use low cost table substitute for golbi ??

Dr. Pushkar Mani

Diabetes Specialist

no there is no problem u can use low cost golbiuse LIVOKIND 300 mg ,its cheap and from good brand as well

Diagnosed for liver cirrhosis due to Budd chiri syndrome. And ballooning done by IV procedure to activate the blocked vein's. Not taking blood thinning tablet to maintain the INT value 3. Now looking for ayurvedic treatment to improve liver cirrhosis conditions.*now taking blood thinning tabletAcitrome 6 mg""

Dr. Aanchal Maheshwari

Ayurveda

Ayurveda do have good treatment for all liver disease, but the case and the individual has to be seen personnaly before prescribing medicine, the bal and prakriti has to be understood before prescribing medicne

Suffering from frequent urination problem for last one month . The problem gets worse in night to till morning. Morning to evening I feel alright. What should I do? Recently I had laparoscopy for gallbladder removal due to call stones.forgot to mention in my last query she has been diagnosed by urinary tract infection and her blood sugar level is alright. following are her problems:- 1.frequent urination 2. Feeling Inflammation all night and it gets worse while passing urine

Dr. Aanchal Maheshwari

Ayurveda

Take chandraprabha vati 2 tablet twice, gokshuradi guggul 2 tablet twice with water, punarnavarisht 20 ml twice with water

Do you have any questions related to Ulyses 150 Tablet ?

CONSULT A DOCTOR ONLINE

User Feedback

Patients taking Ulyses 150 Tablet

Twice A Day

69%

Once A Day

24%

Thrice A Day

What are you using Ulyses Tablet for?

Non-alcoholic*

33%

Cholestatic l*

33%

Alcoholic fat*

17%

Others

17%

*Non-alcoholic fatty liver, Cholestatic liver diseases, Alcoholic fatty liver disease

How much was the improvement?

Excellent

67%

Average

33%

FAQs

Q. When should I take Ulyses?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Ulyses should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Q. Is Ulyses safe?

Ulyses is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

Q. How does Ulyses help the liver?

Ulyses acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Q. Does Ulyses cause weight gain?

Yes, there is a chance of weight gain with Ulyses, but it is not common. The use of Ulyses can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of liver, i.e. when bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

Q. What should I avoid while taking Ulyses?

While taking Ulyses, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Ulyses. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Ulyses. So, ask your doctor about the time gap that should be maintained between Ulyses and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Ulyses.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:
Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:
U.S. National Library of Medicine. Ursodiol. [Accessed 28 Mar. 2019] (online) Available from:

Manufacturer/Marketer Address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

A licensed pharmacy from your nearest location will deliver Ulyses 150 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.