Actibile 150 Tablet

Prescription Required
Manufacturer
Salt Synonyms
Storage
Store below 30°C
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Introduction

Actibile 150 Tablet is used to dissolve certain gallstones and prevent them from forming. It is also used to treat a type of liver disease called primary biliary cirrhosis. It helps break down the cholesterol that has converted into stones in your gallbladder thereby dissolving the stones.

Actibile 150 Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. Take it regularly to get maximum benefit and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.

This medicine's most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them, or they do not go away, let your doctor know.

Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women should discontinue hormonal birth control pills as they can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.

Uses of Actibile Tablet

Benefits of Actibile Tablet

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Actibile 150 Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, you will likely be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

In Treatment of Gallbladder stones

Actibile 150 Tablet is a medicine that helps decreases the amount of cholesterol produced by your liver. It helps to break down cholesterol that has formed into “stones” in the gallbladder. It may take several months to completely dissolve the stone, so you need to take the medicine regularly and as long as the doctor has prescribed it for it to be effective. There might be other medicines and certain lifestyle changes that can reduce your cholesterol level and make gallstones less likely, consult with your doctor.

Side effects of Actibile Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actibile

  • Abdominal pain
  • Diarrhea
  • Hair loss
  • Itching
  • Nausea
  • Rash

How to use Actibile Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Actibile 150 Tablet is to be taken with food.

How Actibile Tablet works

Actibile 150 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Safety advice

Alcohol
UNSAFE
Actibile 150 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
SAFE IF PRESCRIBED
Actibile 150 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Actibile 150 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Actibile 150 Tablet does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Actibile 150 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Actibile 150 Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Actibile Tablet?

If you miss a dose of Actibile 150 Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Actibile 150 Tablet
₹21.54/Tablet
Ursomax 150 Tablet
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Sorbidiol 150 Tablet
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Ursetor 150 Tablet
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Urdiogem 150 Tablet
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Quick tips

  • Actibile 150 Tablet should be taken after a meal with a glass of milk or water.
  • Eat a healthy diet, exercise regularly, and avoid alcohol intake.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
  • Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
  • Do not stop taking the medication without talking to your doctor.

Fact Box

Chemical Class
Bile Acids and Salts
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives

Interaction with drugs

Taking Actibile with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Imudrops, Neoral, Aurosporine
SERIOUS

Patient concerns

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Im pregnant with 8months and having itching in whole body. OT/PT is little higher. Tak Im taking Actibile 300. Prescribed by My doctor. Do I need to consult gastro. This is my second issue. In 1st issue I had same problem. Ans as soon as i delivered baby this all disappeared. Please suggest what to do
Dr. Dharna Gupta
Obstetrics and Gynaecology
Take actibile twice daily.use lactocalamine lotion.No need for gaatro consultYou can take tab cetrizine if itching is too muchFollow your OBS advice
Sir ! For gallbladder stones medicine pl!
Dr. Deepak Kumar Soni
Ayurveda
https://goo.gl/forms/TPKaRvl1NqrBq4Zj2
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User feedback


FAQs

Q. When should I take Actibile 150 Tablet?

The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Actibile 150 Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.

Q. Is Actibile 150 Tablet safe?

Actibile 150 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.

Q. How does Actibile 150 Tablet help the liver?

Actibile 150 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.

Q. Does Actibile 150 Tablet cause weight gain?

Yes, there is a chance of weight gain with Actibile 150 Tablet, but it is not common. The use of Actibile 150 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.

Q. What should I avoid while taking Actibile 150 Tablet?

While taking Actibile 150 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Actibile 150 Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Actibile 150 Tablet. So, ask your doctor about the time gap that should be maintained between Actibile 150 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Actibile 150 Tablet.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Ursodiol. Birmingham, Alabama: Axcan Pharma US, Inc.; 1997 [revised Nov. 2009]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  2. Ursodiol. Bridgewater, New Jersey: Aptalis Pharma US, Inc.; 1997 [revised Jun. 2013]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ursodiol. [Updated 2020 Jan 20]. [Accessed 20 Feb. 2020] (online) Available from:External Link

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India

Expires on or after: January, 2023

A licensed vendor partner from your nearest location will deliver Actibile 150 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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