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09 Dec 2019 | 01:09 PM (IST)
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Tvaptan 30 Tablet


Overview

Introduction

Tvaptan 30 Tablet is a medicine used in the treatment of low levels of sodium in the blood. It treats low levels of sodium in the blood, which can result from conditions such as heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone (SIADH).

Tvaptan 30 Tablet can be taken with or without food. It should be taken exactly as prescribed by your doctor. Your doctor will decide the dose and how often you should take them. You should take this medicine regularly to get the most benefit from it. Do not stop taking the medicine even if you feel better unless the doctor tells you so.

Using this medicine may cause few common side effects such as frequent urge to urinate, nocturia (increased urge to urinate during the night), dryness in mouth, increased thirst, constipation. Let your doctor know if any of these side effects do not go away with time or get worse. Before using this medicine, inform your doctor if you have any problems with your kidneys or liver. While on this medicine, your doctor will closely monitor the sodium levels in your blood. You should also tell your doctor all the other medications you are taking.

Uses of Tvaptan Tablet

Side effects of Tvaptan Tablet

Common
  • Frequent urge to urinate
  • Nocturia (increased urge to urinate during the night)
  • Dryness in mouth
  • Increased thirst
  • Constipation

How to use Tvaptan Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tvaptan 30 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tvaptan Tablet works

Tvaptan 30 Tablet is a vasopressin antagonist. It works by blocking the effect of the hormone vasopressin in the body. This increases urine production, reduces the amount of water in the blood and raises the blood sodium level.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Tvaptan 30 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Tvaptan 30 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Tvaptan 30 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Tvaptan 30 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Tvaptan 30 Tablet is safe to use in patients with kidney disease. No dose adjustment of Tvaptan 30 Tablet is recommended.
However, the use of Tvaptan 30 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Tvaptan 30 Tablet should be used with caution in patients with liver disease. Dose adjustment of Tvaptan 30 Tablet may be needed. Please consult your doctor.
Use of Tvaptan 30 Tablet is not recommended in patients with severe liver disease.

What if you forget to take Tvaptan Tablet?

If you miss a dose of Tvaptan 30 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Tvaptan 30 Tablet
₹207.4/Tablet
Natrise 30 Tablet
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Tolvasca 30 Tablet
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Tolsama 30mg Tablet
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Shiokem 30mg Tablet
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Quick Tips

  • Tvaptan 30 Tablet treats low sodium levels in the blood.
  • It also improves urine flow without causing the body to lose too much sodium as you urinate.
  • Take it at the same time everyday. Take it according to the dose and duration prescribed by your doctor.
  • To avoid dehydration, it is best to drink something as soon as you feel thirsty, but avoid alcoholic drinks.
  • Do not take Tvaptan 30 Tablet if you are unable to urinate, if you are unable to tell when you are thirsty, or if you are severely dehydrated.
  • You will need to be in a hospital under observation any time you start or restart treatment with Tvaptan 30 Tablet.
  • Inform your doctor if you notice problems with speech or muscle control, trouble swallowing, trouble moving your arms and legs, or mood changes.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Patient Concerns

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Are the levels of vitamin b12 low?
Dr. Ila Jain Khandelwal
Pathologist
Dear PATIENT you for sharing your reports with me. The vitamin B12 levels are on the lower side. You should have a diet rich in dairy products since they are rich sources of vitamin B12. You can also start tablet Mecobal once a day for at least 2 months.
Last 2 months I have a problem with constipation and anal irritating. No blood in stool. But tighten. How to cure from that.Always I have a stressful life
Dr. Deepak Kumar Soni
Skin Specialist
https://www.1mg.com/otc/sri-sri-ayurveda-virechana-vati-otc330791One ?one tablet morning & evening after taking food , use at least 1-2 months
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Do you have any questions related to Tvaptan 30 Tablet ?

User Feedback


FAQs

Q. What is the most important information I need to be aware of while taking Tvaptan?

Tvaptan may cause the level of sodium in your blood to increase too quickly. This quick increase in sodium levels [osmotic demyelination syndrome (ODS)] may cause serious nerve damage, which can further cause coma and even death. The symptoms of ODS could be trouble in speaking, trouble in swallowing or a feeling of food or liquid getting stuck while swallowing, drowsiness, confusion, mood changes, fits, trouble controlling body movement (involuntary movement) and weakness in muscles of the arms and legs.

Q. For how long do I need to take Tvaptan?

Tvaptan is used for correction of sodium levels in blood. Though the dose and duration are prescribed by the doctor, Tvaptan should not be taken for more than 30 days. Once the sodium levels return to normal, it can be stopped after talking to the doctor.

Q. Does Tvaptan affect the sugar levels in blood?

Yes, Tvaptan may increase the blood sugar levels. Therefore, patients with diabetes mellitus need to be extra careful while taking Tvaptan and should keep a check on blood sugar levels regularly.

Q. Who should not take Tvaptan?

You should not take Tvaptan if you have low sodium levels, cannot replace fluids by drinking or if you cannot tell when you are thirsty, dizzy or feeling faint or if your kidneys are not working properly because of excessive loss of fluids. You should also avoid Tvaptan if your body is not able to make urine, you are allergic to Tvaptan or if you are on certain medicines which interfere with the working of Tvaptan.

Q. Can I have grapefruit juice while taking Tvaptan?

No, you should not take grapefruit or grapefruit juice while on Tvaptan. The reason being, grapefruit or grapefruit juice may increase the levels of Tvaptan in your blood and your sodium levels may rise too quickly.

Q. What will happen if I take excess of Tvaptan?

You may need urgent medical attention. Call your doctor or seek emergency service at a nearby hospital. Symptoms of taking too much Tolvaptan may include thirst, dry and flaky skin, sunken eyes, rapid heartbeat, rapid and shallow breathing, very low blood pressure, passing more urine than normal and fainting.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 714.
  2. Masters SB. Hypothalamic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 659.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1379-80.
  4. Tolvaptan. Otsuka Pharmaceutical Co.; 2009 [revised Apr. 2013]. [Accesses 04 Apr. 2019] (online) Available from:External Link
  5. ScienceDirect. Tolvaptan. [Accessed 04 Apr. 2019] (online) Available from:External Link
  6. PubChem. Tolvaptan. [Accessed 04 Apr. 2019] (online) Available from:External Link
  7. Tolvaptan. Wexham, UK: Otsuka Pharmaceuticals (UK) Ltd.; 2015 [revised Feb. 2019]. [Accessed 22 Feb. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Best Price
₹663.68
MRP829.6  Get 20% OFF
4 tablets in 1 strip
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