


Trofentyl 50mcg Injection
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 02 Sep 2026 | 01:01 AM (IST)

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General Information



Product introduction
Trofentyl 50mcg Injection is administered by a healthcare professional. You should not self-administer this medicine at home. The dose will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include muscle rigidity, nausea, and vomiting. You may also experience other common side effects such as dizziness, sleepiness, increased or decreased blood pressure, and irregular heartbeat. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding women should consult their doctors before using the medicine.
Uses of Trofentyl Injection
Benefits of Trofentyl Injection
Trofentyl 50mcg Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Trofentyl Injection
- Muscle rigidity
- Nausea
- Vomiting
How to use Trofentyl Injection
How Trofentyl Injection works
Quick tips
- Trofentyl 50mcg Injection helps provide pain relief during surgery.
- It is given by an injection or drip into a vein.
- It may cause dizziness, sleepiness, and headaches. Do not drive or do anything requiring concentration until you know how it affects you.
- Do not drink alcohol or take other medicines that can cause drowsiness while taking Trofentyl 50mcg Injection.
- Your doctor may monitor your breathing, blood pressure and heart rate while you receive this medication.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Safety advice

Alcohol

Pregnancy

Breast feeding
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.

Driving

Kidney
Caution should be excercised in patients with underlying kidney disease.

Liver

Interaction with drugs
Selegiline (Oral Route)
Tranylcypromine (Oral Route)
Naltrexone (Oral Route)
Ziprasidone (Oral Route)
Alprazolam (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 545-46.
- Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 505-506.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 539-41.
- Fentanyl. Gloucester Business Park Gloucester: Hameln Pharmaceuticals Ltd.; 10 Jan. 2011 [revised 28 Oct. 2018]. [Accessed 02 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:




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