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Naltrexone

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 28 Mar 2025 | 06:27 AM (UTC)

Naltrexone Uses

Naltrexone is used in the treatment of opioid toxicity, alcohol addiction and opioid dependence.

How Naltrexone works

Naltrexone is an opioid antagonist. It works by blocking the euphoric feelings (highs) that you may experience after taking opiates and alcohol. This reduces craving and helps you remain off of them.

Common side effects of Naltrexone

Joint pain, Muscle pain, Insomnia (difficulty in sleeping), Headache, Nausea, Nervousness, Abdominal cramp
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Expert advice for Naltrexone

  • Take it at the same time every day to help you remember to take it.
  • Do not consume opioid derivatives while on this treatment.
  • Do not drive or do anything requiring concentration until you know how Naltrexone affects you.
  • Your doctor may check your liver function before starting treatment and regularly thereafter.
  • Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Frequently asked questions for Naltrexone

No, Naltrexone must be taken as long as prescribed by your doctor
Caution has to be exercised when Naltrexone is taken with alprazolam and its derivatives
No, both suboxone and subtext are used in opioid withdrawal. Hence they should not be taken with naltrexone, as an additive effect leading to side effects may occur. Always follow the instructions of the doctor
No, Naltrexone does not make you high but, may rarely make you sleepy
Naltrexone has no known effects on pain and is not indicated for weight loss
Yes, Naltrexone helps reduce opiate cravings
No, Naltrexone does not test positive for opiates.