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    Information about Naltrexone

    Naltrexone uses

    Naltrexone is used in the treatment of opioid dependence and alcohol addiction.

    How naltrexone works

    Naltrexone is an opioid antagonist. It works by blocking the euphoric feelings (highs) that you may experience after taking opiates and alcohol. This reduces craving and helps you remain off of them.

    Common side effects of naltrexone

    Joint pain, Muscle pain, Insomnia (difficulty in sleeping), Weakness, Anxiety, Restlessness, Fainting, Increased thirst, Decreased libido, Decreased sexual function
    Content Details
    Written By
    Dr. Swati Mishra
    Reviewed By
    Dr. Varun Gupta
    MD (Pharmacology), MBBS
    Last updated on:
    18 Feb 2020 | 05:21 PM (IST)
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    Read Our Editorial Policy

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    Expert advice for Naltrexone

    • Take it at the same time every day to help you remember to take it.
    • Do not consume opioid derivatives while on this treatment.
    • Do not drive or do anything requiring concentration until you know how Naltrexone affects you.
    • Your doctor may check your liver function before starting treatment and regularly thereafter.
    • Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

    Frequently asked questions for Naltrexone


    Q. Can you take Naltrexone forever?

    No, Naltrexone must be taken as long as prescribed by your doctor

    Q. Can you take Naltrexone with Xanax (alprazolam)?

    Caution has to be exercised when Naltrexone is taken with alprazolam and its derivatives

    Q. Can you take naltrexone with suboxone (naloxone and buprenorphine)/ Subtex (buprenorphine)?

    No, both suboxone and subtext are used in opioid withdrawal. Hence they should not be taken with naltrexone, as an additive effect leading to side effects may occur. Always follow the instructions of the doctor

    Q. Does Naltrexone make you high/ sleepy?

    No, Naltrexone does not make you high but, may rarely make you sleepy

    Q. Does Naltrexone help with pain/ for weight loss?

    Naltrexone has no known effects on pain and is not indicated for weight loss

    Q. Does Naltrexone help with opiate cravings?

    Yes, Naltrexone helps reduce opiate cravings

    Q. Does Naltrexone test positive for opiates?

    No, Naltrexone does not test positive for opiates.