
Trexe 500mg Tablet
Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 05 Feb 2026 | 02:41 PM (IST)
Trexe 500mg Tablet is used to treat bleeding. It helps to prevent or reduce bleeding in conditions like tooth removal, heavy periods, dysfunctional uterine bleeding, nosebleeds, and in any oral, prostate, or bladder surgery.
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General Information
The content is shown in English



Product introduction
Trexe 500mg Tablet is an anti-fibrinolytic. It works by preventing the breakdown of clots, which leads to the stoppage of bleeding. This injection must be administered under the supervision of a healthcare professional. You should not take it if you have any known allergy to this injection.
The most common side effects of this medicine include vomiting, nausea, and diarrhoea. Inform your doctor if you have undergone any cardiac surgery or if you are suffering from any kidney disease. This injection is safe to use in pregnant or breastfeeding mothers. It is also safe to use in patients suffering from liver diseases.
Uses of Trexe Tablet
Benefits of Trexe Tablet
Bleeding
Trexe 500mg Tablet is commonly used to manage and control excessive bleeding in various medical situations, such as heavy menstrual bleeding, surgery, or trauma. It works by helping the blood clot more effectively, which reduces the amount and duration of bleeding. This can be especially helpful in conditions where bleeding is prolonged or unusually heavy, supporting quicker recovery and reducing the need for blood transfusions.
Trexe 500mg Tablet is commonly used to manage and control excessive bleeding in various medical situations, such as heavy menstrual bleeding, surgery, or trauma. It works by helping the blood clot more effectively, which reduces the amount and duration of bleeding. This can be especially helpful in conditions where bleeding is prolonged or unusually heavy, supporting quicker recovery and reducing the need for blood transfusions.
Side effects of Trexe Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trexe
- Vomiting
- Nausea
- Diarrhea
How to use Trexe Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trexe 500mg Tablet should be taken with or after food.
How Trexe Tablet works
Trexe 500mg Tablet is an anti-fibrinolytic. It works by preventing the breakdown of blood clots to control excessive bleeding during periods, or after surgery.
All substitutes for Trexe 500mg Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Trexe 500mg Tablet helps prevent or reduce heavy bleeding post surgery and in conditions such as heavy periods, dysfunctional uterine bleeding, and nosebleeds.
- It is given as a slow injection into a vein.
- Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.
- Your doctor may monitor your vision regularly while you are taking this medicine.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Trexe 500mg Tablet. Please consult your doctor.

Pregnancy
UNSAFE
Trexe 500mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding
CAUTION
Trexe 500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
CONSULT YOUR DOCTOR
It is not known whether Trexe 500mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Trexe 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
SAFE IF PRESCRIBED
Trexe 500mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.
Interaction with drugs
Taking Trexe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening
Phenindione (Oral Route)
Do not consume Phenindione with Tranexamic Acid. If concurrent use is essential, please consult your doctor.
Severe
Warfarin (Oral Route)
Do not consume Warfarin with Tranexamic Acid. If concurrent use is essential, please consult your doctor.
Moderate
Medroxyprogesterone acetate (Injection Route)
Do not use Medroxyprogesterone acetate with Tranexamic Acid. If concurrent use is essential, talk to your doctor.
Frequently asked questions
No, Trexe 500mg Tablet should not be administered by injection into the muscles. It should be given strictly through slow injection into the veins to prevent side effects.
Every medicine has its own side effects and these side effects are unlikely to happen if taken as directed. Usually, the benefits of the medicine are greater than the risk of side effects. Trexe 500mg Tablet can rarely cause serious side-effects which can be dangerous, like anaphylaxis (red and lumpy skin rash, difficulty breathing, swelling of face, mouth, lips or eyelids), clot in another part of the body or eye problems. Do consult your doctor before you start this medication and follow the instructions strictly as given.
Yes, there are chances of possible disturbances in your colour vision when you are on long term treatment with Trexe 500mg Tablet. Hence, regular eye check should be done during treatment and doctor should be informed if you notice any change in your vision. If any changes are seen your doctor may stop the medicine and suggest an alternative.
Trexe 500mg Tablet promotes blood clotting and can rarely cause blood clot to travel to the lungs (pulmonary embolism) which can turn fatal sometimes. Pulmonary embolism is not a common side effect in patients taking Trexe 500mg Tablet but can occur in overdosing, patients with long bedrest or prone individuals. Evidence suggests that the increased risk of clot can be due to some other additional risk factors as well.
Trexe 500mg Tablet can be taken with or without food with a glass of water. The medicine should be swallowed as a whole and should not be crushed or chewed.
No, Trexe 500mg Tablet does not affect fertility. It is taken for heavy menstrual bleeding and evidence suggests no interference of this medicine with ovulation (release of eggs from the ovaries). Therefore, this medicine is not a type of contraceptive medicine and it will not affect your chances of becoming pregnant.
Yes, Trexe 500mg Tablet can be used for nose bleeding. It helps to clot the blood and prevent bleeding. If the bleeding is frequently observed then the medicine can be even taken for a week.
Fact Box
Chemical Class
Amino acid derivative
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Antifibrinolytic Agents
References
- Tranexamic Acid. London, UK: ADVANZ Pharma; 2013 [revised 5 Jul. 2018]. [Accessed 17 Apr. 2019] (online) Available from:
- Tranexamic Acid. New York, New York: Pharmacia & Upjohn Co.; 2011. [Accessed 07 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:
- Tranexamic Acid Injection [Patient Information Leaflet]. Haridwar, Uttarakhand: Skymap Healthcare Pvt. Ltd; [Accessed 05 Jan. 2026] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Zee Laboratories
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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