Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolbin 1000 mg Tablet is to be taken with food.

How Tolbin Tablet works

Tolbin 1000 mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

In Depth Information on Tolbin Tablet

Expert advice for Tolbin Tablet

Your doctor has prescribed Tolbin 1000 mg Tablet to cure your infection and improve symptoms.
You can take it with food or on an empty stomach.
Tell your doctor immediately if you experience vision changes or eye pain, swelling of face, rashes, breathing difficulty, numbness, headache, fever or chills.

Tolbin Tablet related warnings

Special precautions for Tolbin Tablet

Alcohol

Interaction with alcohol is unknown. Please consult your doctor.

Pregnancy

WEIGH RISKS VS BENEFITS

Tolbin 1000 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation

SAFE

Tolbin 1000 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.

Driving

Do not drive unless you are feeling well.
Tolbin 1000 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.

Kidney

CAUTION

Tolbin 1000 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Tolbin 1000 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.

Liver

CAUTION

Tolbin 1000 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Tolbin 1000 mg Tablet may be needed. Please consult your doctor.

What if you miss a dose of Tolbin Tablet?

If you miss a dose of Tolbin 1000 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions about Tolbin Tablet

Frequently asked questions about Ethambutol

Q. Does Tolbin cause blindness?

Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Tolbin which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. Does Tolbin induce hyperuricemia/how does Tolbin induce hyperuricemia?

Yes. Increase in blood levels of uric acid is a side effect of Tolbin. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys

Q. How does Tolbin work in the body?

Tolbin is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria

Q. What is Tolbin toxicity/How does Tolbin cause optic neuritis/how does Tolbin affect vision?

Tolbin toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Tolbin treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Tolbin induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. What does Tolbin treat?

Tolbin is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Tolbin bacteriostatic or bactericidal?

Tolbin is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)

Q. Is Tolbin hepatotoxic?

Liver toxicities are among the known side effects of Tolbin. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Tolbin) treatment for tuberculosis. Please contact your doctor before taking Tolbin if you have any liver problems

Q. Is Tolbin toxicity reversible?

In most cases Tolbin toxicities are related to dose (depends upon the quantity of Tolbin you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases

Q. Is Tolbin chemotherapy?

Tolbin is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Tolbin is effective against?

Tolbin is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).