Themipath 50mg Injection

Pethidine (50mg)

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Themipath 50mg Injection is a pain-relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment for an extended period of time.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information

Contains

Pethidine (50mg)

Marketer

Themis Medicare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Themipath 50mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, drowsiness, fatigue, vomiting, constipation, dry mouth, and sweating. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Themipath Injection

Moderate to severe pain

Benefits of Themipath Injection

Moderate to severe pain
Themipath 50mg Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Themipath Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Themipath

Injection site reactions (pain, swelling, redness)
Headache
Drowsiness
Fatigue
Vomiting
Constipation
Dryness in mouth
Sweating

How to use Themipath Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Themipath Injection works

Themipath 50mg Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.

Quick tips

Use Themipath 50mg Injection as instructed by your doctor. Never take in greater amounts or more often than prescribed.
It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Avoid consuming alcohol when taking the Themipath 50mg Injection, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Store opioid pain relievers in a safe place and out of reach of others.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Themipath 50mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Themipath 50mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Themipath 50mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

UNSAFE

Themipath 50mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Themipath 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Themipath 50mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Themipath with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Pethidine. If Moclobemide is essential, ensure a gap of at least 24 hours after discontinuing Pethidine. Please consult your doctor.

Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Pethidine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Pethidine.

Life-threatening

Safinamide (Oral Route)

Do not consume Safinamide with Pethidine. If Safinamide is essential, ensure a gap of at least 1 week after discontinuing Pethidine. Please consult your doctor. Please consult your doctor.

Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Pethidine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Pethidine. Please consult your doctor.

Life-threatening

Rasagiline (Oral Route)

Do not consume Rasagiline with Pethidine. If Rasagiline is essential, ensure a gap of at least 2 weeks after discontinuing Pethidine. Please consult your doctor.

Frequently asked questions

Is there anything I need to be careful about while on therapy with Themipath 50mg Injection?

Themipath 50mg Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Opioids

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.

Vendor Details

Country of origin: India

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Themipath 50mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Themipath Injection

Benefits of Themipath Injection

Side effects of Themipath Injection

How to use Themipath Injection

How Themipath Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Moclobemide (Oral Route)

Naltrexone (Oral Route)

Safinamide (Oral Route)

Selegiline (Oral Route)

Rasagiline (Oral Route)

Frequently asked questions

Is there anything I need to be careful about while on therapy with Themipath 50mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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